| Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans PS Arunachalam, F Wimmers, CKP Mok, RAPM Perera, M Scott, T Hagan, ... Science 369 (6508), 1210-1220, 2020 | 1165 | 2020 |
| Antibiotics-driven gut microbiome perturbation alters immunity to vaccines in humans T Hagan, M Cortese, N Rouphael, C Boudreau, C Linde, MS Maddur, ... Cell 178 (6), 1313-1328. e13, 2019 | 539 | 2019 |
| Systems vaccinology of the BNT162b2 mRNA vaccine in humans PS Arunachalam, MKD Scott, T Hagan, C Li, Y Feng, F Wimmers, ... Nature 596 (7872), 410-416, 2021 | 476 | 2021 |
| Systems analysis of immunity to influenza vaccination across multiple years and in diverse populations reveals shared molecular signatures HI Nakaya, T Hagan, SS Duraisingham, EK Lee, M Kwissa, N Rouphael, ... Immunity 43 (6), 1186-1198, 2015 | 327 | 2015 |
| Metabolic phenotypes of response to vaccination in humans S Li, NL Sullivan, N Rouphael, T Yu, S Banton, MS Maddur, ... Cell 169 (5), 862-877. e17, 2017 | 275 | 2017 |
| The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination F Wimmers, M Donato, A Kuo, T Ashuach, S Gupta, C Li, M Dvorak, ... Cell 184 (15), 3915-3935. e21, 2021 | 211 | 2021 |
| Systems vaccinology: enabling rational vaccine design with systems biological approaches T Hagan, HI Nakaya, S Subramaniam, B Pulendran Vaccine 33 (40), 5294-5301, 2015 | 126 | 2015 |
| mTOR regulates metabolic adaptation of APCs in the lung and controls the outcome of allergic inflammation C Sinclair, G Bommakanti, L Gardinassi, J Loebbermann, MJ Johnson, ... Science 357 (6355), 1014-1021, 2017 | 118 | 2017 |
| Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination S Fourati, LE Tomalin, MP Mulè, DG Chawla, B Gerritsen, D Rychkov, ... Nature immunology 23 (12), 1777-1787, 2022 | 84* | 2022 |
| Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses T Hagan, B Gerritsen, LE Tomalin, S Fourati, MP Mulè, DG Chawla, ... Nature immunology 23 (12), 1788-1798, 2022 | 81 | 2022 |
| Engineering cell–material interfaces for long-term expansion of human pluripotent stem cells CW Chang, Y Hwang, D Brafman, T Hagan, C Phung, S Varghese Biomaterials 34 (4), 912-921, 2013 | 66 | 2013 |
| Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: results from the IMPACC study A Ozonoff, J Schaenman, ND Jayavelu, CE Milliren, CS Calfee, CB Cairns, ... EBioMedicine 83, 2022 | 47 | 2022 |
| SREBP signaling is essential for effective B cell responses W Luo, JZ Adamska, C Li, R Verma, Q Liu, T Hagan, F Wimmers, S Gupta, ... Nature immunology 24 (2), 337-348, 2023 | 45 | 2023 |
| Will systems biology deliver its promise and contribute to the development of new or improved vaccines? From data to understanding through systems biology T Hagan, B Pulendran Cold Spring Harbor perspectives in biology 10 (8), a028894, 2018 | 41 | 2018 |
| Multi-omics analysis of mucosal and systemic immunity to SARS-CoV-2 after birth F Wimmers, AR Burrell, Y Feng, H Zheng, PS Arunachalam, M Hu, ... Cell 186 (21), 4632-4651. e23, 2023 | 33 | 2023 |
| Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity TY Shao, P Kakade, JN Witchley, C Frazer, KL Murray, IV Ene, ... Cell reports 39 (7), 2022 | 24 | 2022 |
| The immune signatures data resource, a compendium of systems vaccinology datasets J Diray-Arce, HER Miller, E Henrich, B Gerritsen, MP Mulè, S Fourati, ... Scientific data 9 (1), 635, 2022 | 21 | 2022 |
| Ablation of Adar1 in myeloid cells imprints a global antiviral state in the lung and heightens early immunity against SARS-CoV-2 JZ Adamska, R Verma, S Gupta, T Hagan, F Wimmers, K Floyd, Q Li, ... Cell reports 42 (1), 2023 | 4 | 2023 |
| Acute and persistent responses after H5N1 vaccination in humans R Apps, A Biancotto, J Candia, Y Kotliarov, S Perl, F Cheung, R Farmer, ... Cell Reports 43 (9), 2024 | 3 | 2024 |
| System vaccinology analysis of predictors and mechanisms of antibody response durability to multiple vaccines in humans M Cortese, T Hagan, N Rouphael, SY Wu, X Xie, D Kazmin, F Wimmers, ... Nature Immunology, 1-15, 2025 | | 2025 |
