Molecular genetics of prostate cancer: new prospects for old challenges MM Shen, C Abate-Shen Genes & development 24 (18), 1967-2000, 2010 | 1365 | 2010 |
Molecular genetics of prostate cancer C Abate-Shen, MM Shen Genes & development 14 (19), 2410-2434, 2000 | 1141 | 2000 |
Evidence for evolutionary conservation of sex-determining genes CS Raymond, CE Shamu, MM Shen, KJ Seifert, B Hirsch, J Hodgkin, ... Nature 391 (6668), 691-695, 1998 | 955 | 1998 |
Murine FGFR-1 is required for early postimplantation growth and axial organization. CX Deng, A Wynshaw-Boris, MM Shen, C Daugherty, DM Ornitz, P Leder Genes & development 8 (24), 3045-3057, 1994 | 915 | 1994 |
A luminal epithelial stem cell that is a cell of origin for prostate cancer XI Wang, MK Julio, KD Economides, D Walker, H Yu, MV Halili, YP Hu, ... Nature 461 (7263), 495-500, 2009 | 891 | 2009 |
Roles for Nkx3. 1 in prostate development and cancer R Bhatia-Gaur, AA Donjacour, PJ Sciavolino, M Kim, N Desai, P Young, ... Genes & development 13 (8), 966-977, 1999 | 837 | 1999 |
Tumor evolution and drug response in patient-derived organoid models of bladder cancer SH Lee, W Hu, JT Matulay, MV Silva, TB Owczarek, K Kim, CW Chua, ... Cell 173 (2), 515-528. e17, 2018 | 775 | 2018 |
Nodal signaling: developmental roles and regulation MM Shen Oxford University Press for The Company of Biologists Limited 134 (6), 1023-1034, 2007 | 718 | 2007 |
Nodal signalling in vertebrate development AF Schier, MM Shen Nature 403 (6768), 385-389, 2000 | 634 | 2000 |
Cripto is required for correct orientation of the anterior–posterior axis in the mouse embryo J Ding, L Yang, YT Yan, A Chen, N Desai, A Wynshaw-Boris, MM Shen Nature 395 (6703), 702-707, 1998 | 560 | 1998 |
Essential role for p38α mitogen-activated protein kinase in placental angiogenesis JS Mudgett, J Ding, L Guh-Siesel, NA Chartrain, L Yang, S Gopal, ... Proceedings of the National Academy of Sciences 97 (19), 10454-10459, 2000 | 498 | 2000 |
Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport DE Sleat, JA Wiseman, M El-Banna, SM Price, L Verot, MM Shen, GS Tint, ... Proceedings of the National Academy of Sciences 101 (16), 5886-5891, 2004 | 433 | 2004 |
Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis MJ Kim, RD Cardiff, N Desai, WA Banach-Petrosky, R Parsons, MM Shen, ... Proceedings of the National Academy of Sciences 99 (5), 2884-2889, 2002 | 425 | 2002 |
Inactivation of p53 and Pten promotes invasive bladder cancer AM Puzio-Kuter, M Castillo-Martin, CW Kinkade, X Wang, TH Shen, ... Genes & development 23 (6), 675-680, 2009 | 401 | 2009 |
Single luminal epithelial progenitors can generate prostate organoids in culture CW Chua, M Shibata, M Lei, R Toivanen, LMJ Barlow, SK Bergren, ... Nature cell biology 16 (10), 951-961, 2014 | 393 | 2014 |
Transdifferentiation as a mechanism of treatment resistance in a mouse model of castration-resistant prostate cancer M Zou, R Toivanen, A Mitrofanova, N Floch, S Hayati, Y Sun, ... Cancer discovery 7 (7), 736-749, 2017 | 361 | 2017 |
Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity ZA Wang, A Mitrofanova, SK Bergren, C Abate-Shen, RD Cardiff, ... Nature cell biology 15 (3), 274-283, 2013 | 361 | 2013 |
Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development H Oda, I Okamoto, N Murphy, J Chu, SM Price, MM Shen, ... Molecular and cellular biology 29 (8), 2278-2295, 2009 | 361 | 2009 |
Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects RN Bamford, E Roessler, RD Burdine, U Şaplakoğlu, M Splitt, J Towbin, ... Nature genetics 26 (3), 365-369, 2000 | 357 | 2000 |
Heterodimerization of Msx and Dlx homeoproteins results in functional antagonism H Zhang, G Hu, H Wang, P Sciavolino, N Iler, MM Shen, C Abate-Shen Molecular and cellular biology 17 (5), 2920-2932, 1997 | 351 | 1997 |