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Ian Beddows
Ian Beddows
Bioinformatics Research Scientist, Van Andel Institute
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα vai.org
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Gut microbiota dysbiosis is associated with elevated bile acids in Parkinson’s disease
P Li, BA Killinger, E Ensink, I Beddows, A Yilmaz, N Lubben, J Lamp, ...
Metabolites 11 (1), 29, 2021
1002021
Desmoplastic small round cell tumor is dependent on the EWS-WT1 transcription factor
JM Gedminas, MH Chasse, M McBrairty, I Beddows, SM Kitchen-Goosen, ...
Oncogenesis 9 (4), 41, 2020
522020
Evaluation of whole-genome DNA methylation sequencing library preparation protocols
J Morrison, JM Koeman, BK Johnson, KK Foy, I Beddows, W Zhou, ...
Epigenetics & chromatin 14 (1), 28, 2021
432021
Population genomics in wild tomatoes—the interplay of divergence and admixture
I Beddows, A Reddy, T Kloesges, LE Rose
Genome biology and evolution 9 (11), 3023-3038, 2017
352017
CDK9 Blockade exploits context-dependent transcriptional changes to improve activity and limit toxicity of mithramycin for Ewing sarcoma
G Flores, JH Everett, EA Boguslawski, BM Oswald, ZB Madaj, I Beddows, ...
Molecular cancer therapeutics 19 (5), 1183-1196, 2020
232020
Detection of chemotherapy-resistant pancreatic cancer using a glycan biomarker, sTRA
CF Gao, L Wisniewski, Y Liu, B Staal, I Beddows, D Plenker, M Aldakkak, ...
Clinical Cancer Research 27 (1), 226-236, 2021
202021
Factors determining hybridization rate in plants: A case study in Michigan
I Beddows, LE Rose
Perspectives in Plant Ecology, Evolution and Systematics 34, 51-60, 2018
192018
Loss of microRNA‐21 leads to profound stromal remodeling and short survival in K‐Ras‐driven mouse models of pancreatic cancer
J Schipper, JJ Westerhuis, I Beddows, Z Madaj, D Monsma, G Hostetter, ...
International journal of cancer 147 (8), 2265-2278, 2020
172020
Lurbinectedin inhibits the EWS–WT1 transcription factor in desmoplastic small round cell tumor
JM Gedminas, R Kaufman, EA Boguslawski, AC Gross, M Adams, ...
Molecular cancer therapeutics 21 (8), 1296-1305, 2022
142022
BISCUIT: an efficient, standards-compliant tool suite for simultaneous genetic and epigenetic inference in bulk and single-cell studies
W Zhou, BK Johnson, J Morrison, I Beddows, J Eapen, E Katsman, ...
Nucleic Acids Research 52 (6), e32-e32, 2024
112024
Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor
MH Chasse, BK Johnson, EA Boguslawski, KM Sorensen, JE Rosien, ...
EMBO Molecular Medicine 13 (2), e12640, 2021
112021
Cell state of origin impacts development of distinct endometriosis-related ovarian carcinoma histotypes
I Beddows, H Fan, K Heinze, BK Johnson, A Leonova, J Senz, S Djirackor, ...
Cancer Research 84 (1), 26-38, 2024
102024
PGC-1β maintains mitochondrial metabolism and restrains inflammatory gene expression
H Guak, RD Sheldon, I Beddows, A Vander Ark, MJ Weiland, H Shen, ...
Scientific Reports 12 (1), 16028, 2022
72022
Generation of a new frizzled 2 flox mouse model to clarify its role in development
MN Michalski, CR Diegel, ZA Zhong, K Suino-Powell, L Blazer, J Adams, ...
Biorxiv, 2021.01. 27.428341, 2021
52021
Gut microbiome dysbiosis is associated with elevated toxic bile acids in Parkinson’s disease
P Li, BA Killinger, I Beddows, E Ensink, A Yilmaz, N Lubben, J Lamp, ...
bioRxiv, 2020.09. 26.279851, 2020
52020
NF1 deficiency drives metabolic reprogramming in ER+ breast cancer
RRJ House, EA Tovar, LN Redlon, CJ Essenburg, PS Dischinger, AE Ellis, ...
Molecular Metabolism 80, 101876, 2024
42024
Intergenerational metabolic priming by sperm piRNAs
A Lempradl, U Kugelberg, M Iconomou, I Beddows, D Nätt, E Casas, ...
BioRxiv, 2021.03. 29.436592, 2021
42021
Formation of templated inclusions in a forebrain α-synuclein mouse model is independent of LRRK2
DJ Dues, Y Ma, APT Nguyen, AV Offerman, I Beddows, DJ Moore
Neurobiology of disease 188, 106338, 2023
22023
Nf1 deficiency accelerates mammary development and promotes luminal-basal plasticity
EA Tovar, M Arumugam, CJ Essenburg, PS Dischinger, JL Grit, ...
bioRxiv, 2022.12. 22.520633, 2022
22022
Examining the molecular mechanisms contributing to the success of an invasive species across different ecosystems
SK Lamar, I Beddows, CG Partridge
Ecology and Evolution 10 (18), 10254-10270, 2020
22020
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