Gut microbiota dysbiosis is associated with elevated bile acids in Parkinson’s disease P Li, BA Killinger, E Ensink, I Beddows, A Yilmaz, N Lubben, J Lamp, ... Metabolites 11 (1), 29, 2021 | 100 | 2021 |
Desmoplastic small round cell tumor is dependent on the EWS-WT1 transcription factor JM Gedminas, MH Chasse, M McBrairty, I Beddows, SM Kitchen-Goosen, ... Oncogenesis 9 (4), 41, 2020 | 52 | 2020 |
Evaluation of whole-genome DNA methylation sequencing library preparation protocols J Morrison, JM Koeman, BK Johnson, KK Foy, I Beddows, W Zhou, ... Epigenetics & chromatin 14 (1), 28, 2021 | 43 | 2021 |
Population genomics in wild tomatoes—the interplay of divergence and admixture I Beddows, A Reddy, T Kloesges, LE Rose Genome biology and evolution 9 (11), 3023-3038, 2017 | 35 | 2017 |
CDK9 Blockade exploits context-dependent transcriptional changes to improve activity and limit toxicity of mithramycin for Ewing sarcoma G Flores, JH Everett, EA Boguslawski, BM Oswald, ZB Madaj, I Beddows, ... Molecular cancer therapeutics 19 (5), 1183-1196, 2020 | 23 | 2020 |
Detection of chemotherapy-resistant pancreatic cancer using a glycan biomarker, sTRA CF Gao, L Wisniewski, Y Liu, B Staal, I Beddows, D Plenker, M Aldakkak, ... Clinical Cancer Research 27 (1), 226-236, 2021 | 20 | 2021 |
Factors determining hybridization rate in plants: A case study in Michigan I Beddows, LE Rose Perspectives in Plant Ecology, Evolution and Systematics 34, 51-60, 2018 | 19 | 2018 |
Loss of microRNA‐21 leads to profound stromal remodeling and short survival in K‐Ras‐driven mouse models of pancreatic cancer J Schipper, JJ Westerhuis, I Beddows, Z Madaj, D Monsma, G Hostetter, ... International journal of cancer 147 (8), 2265-2278, 2020 | 17 | 2020 |
Lurbinectedin inhibits the EWS–WT1 transcription factor in desmoplastic small round cell tumor JM Gedminas, R Kaufman, EA Boguslawski, AC Gross, M Adams, ... Molecular cancer therapeutics 21 (8), 1296-1305, 2022 | 14 | 2022 |
BISCUIT: an efficient, standards-compliant tool suite for simultaneous genetic and epigenetic inference in bulk and single-cell studies W Zhou, BK Johnson, J Morrison, I Beddows, J Eapen, E Katsman, ... Nucleic Acids Research 52 (6), e32-e32, 2024 | 11 | 2024 |
Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor MH Chasse, BK Johnson, EA Boguslawski, KM Sorensen, JE Rosien, ... EMBO Molecular Medicine 13 (2), e12640, 2021 | 11 | 2021 |
Cell state of origin impacts development of distinct endometriosis-related ovarian carcinoma histotypes I Beddows, H Fan, K Heinze, BK Johnson, A Leonova, J Senz, S Djirackor, ... Cancer Research 84 (1), 26-38, 2024 | 10 | 2024 |
PGC-1β maintains mitochondrial metabolism and restrains inflammatory gene expression H Guak, RD Sheldon, I Beddows, A Vander Ark, MJ Weiland, H Shen, ... Scientific Reports 12 (1), 16028, 2022 | 7 | 2022 |
Generation of a new frizzled 2 flox mouse model to clarify its role in development MN Michalski, CR Diegel, ZA Zhong, K Suino-Powell, L Blazer, J Adams, ... Biorxiv, 2021.01. 27.428341, 2021 | 5 | 2021 |
Gut microbiome dysbiosis is associated with elevated toxic bile acids in Parkinson’s disease P Li, BA Killinger, I Beddows, E Ensink, A Yilmaz, N Lubben, J Lamp, ... bioRxiv, 2020.09. 26.279851, 2020 | 5 | 2020 |
NF1 deficiency drives metabolic reprogramming in ER+ breast cancer RRJ House, EA Tovar, LN Redlon, CJ Essenburg, PS Dischinger, AE Ellis, ... Molecular Metabolism 80, 101876, 2024 | 4 | 2024 |
Intergenerational metabolic priming by sperm piRNAs A Lempradl, U Kugelberg, M Iconomou, I Beddows, D Nätt, E Casas, ... BioRxiv, 2021.03. 29.436592, 2021 | 4 | 2021 |
Formation of templated inclusions in a forebrain α-synuclein mouse model is independent of LRRK2 DJ Dues, Y Ma, APT Nguyen, AV Offerman, I Beddows, DJ Moore Neurobiology of disease 188, 106338, 2023 | 2 | 2023 |
Nf1 deficiency accelerates mammary development and promotes luminal-basal plasticity EA Tovar, M Arumugam, CJ Essenburg, PS Dischinger, JL Grit, ... bioRxiv, 2022.12. 22.520633, 2022 | 2 | 2022 |
Examining the molecular mechanisms contributing to the success of an invasive species across different ecosystems SK Lamar, I Beddows, CG Partridge Ecology and Evolution 10 (18), 10254-10270, 2020 | 2 | 2020 |