Παρακολούθηση
Joshua Kritzer
Joshua Kritzer
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα tufts.edu - Αρχική σελίδα
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Παρατίθεται από
Παρατίθεται από
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Helical β-peptide inhibitors of the p53-hDM2 interaction
JA Kritzer, JD Lear, ME Hodsdon, A Schepartz
Journal of the American Chemical Society 126 (31), 9468-9469, 2004
3902004
Getting in shape: controlling peptide bioactivity and bioavailability using conformational constraints
JE Bock, J Gavenonis, JA Kritzer
ACS chemical biology 8 (3), 488-499, 2013
2462013
β-Peptides as inhibitors of protein–protein interactions
JA Kritzer, OM Stephens, DA Guarracino, SK Reznik, A Schepartz
Bioorganic & medicinal chemistry 13 (1), 11-16, 2005
2362005
Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models
LJ Su, PK Auluck, TF Outeiro, E Yeger-Lotem, JA Kritzer, DF Tardiff, ...
Disease models & mechanisms 3 (3-4), 194-208, 2010
2262010
Comprehensive analysis of loops at protein-protein interfaces for macrocycle design
J Gavenonis, BA Sheneman, TR Siegert, MR Eshelman, JA Kritzer
Nature chemical biology 10 (9), 716-722, 2014
2232014
Rapid selection of cyclic peptides that reduce α-synuclein toxicity in yeast and animal models
JA Kritzer, S Hamamichi, JM McCaffery, S Santagata, TA Naumann, ...
Nature chemical biology 5 (9), 655-663, 2009
1772009
Cell penetration profiling using the chloroalkane penetration assay
L Peraro, KL Deprey, MK Moser, Z Zou, HL Ball, B Levine, JA Kritzer
Journal of the American Chemical Society 140 (36), 11360-11369, 2018
1492018
Diversity-oriented stapling yields intrinsically cell-penetrant inducers of autophagy
L Peraro, Z Zou, KM Makwana, AE Cummings, HL Ball, H Yu, YS Lin, ...
Journal of the American Chemical Society 139 (23), 7792-7802, 2017
1472017
Emerging methods and design principles for cell‐penetrant peptides
L Peraro, JA Kritzer
Angewandte Chemie International Edition 57 (37), 11868-11881, 2018
1452018
Relationship between Side Chain Structure and 14-Helix Stability of β3-Peptides in Water
JA Kritzer, J Tirado-Rives, SA Hart, JD Lear, WL Jorgensen, A Schepartz
Journal of the American Chemical Society 127 (1), 167-178, 2005
1372005
Miniature protein inhibitors of the p53–hDM2 interaction
JA Kritzer, R Zutshi, M Cheah, FA Ran, R Webman, TM Wongjirad, ...
ChemBioChem 7 (1), 29-31, 2006
1092006
Solution structure of a β-peptide ligand for hDM2
JA Kritzer, ME Hodsdon, A Schepartz
Journal of the American Chemical Society 127 (12), 4118-4119, 2005
992005
A rapid library screen for tailoring β-peptide structure and function
JA Kritzer, NW Luedtke, EA Harker, A Schepartz
Journal of the American Chemical Society 127 (42), 14584-14585, 2005
852005
Trapped! A critical evaluation of methods for measuring total cellular uptake versus cytosolic localization
K Deprey, L Becker, J Kritzer, A Plückthun
Bioconjugate chemistry 30 (4), 1006-1027, 2019
782019
Analysis of loops that mediate protein–protein interactions and translation into submicromolar inhibitors
TR Siegert, MJ Bird, KM Makwana, JA Kritzer
Journal of the American Chemical Society 138 (39), 12876-12884, 2016
682016
A critical analysis of methods used to investigate the cellular uptake and subcellular localization of RNA therapeutics
K Deprey, N Batistatou, JA Kritzer
Nucleic acids research 48 (14), 7623-7639, 2020
632020
Conformational restriction of peptides using dithiol bis-alkylation
L Peraro, TR Siegert, JA Kritzer
Methods in enzymology 580, 303-332, 2016
622016
Metal-binding and redox properties of substituted linear and cyclic ATCUN motifs
KP Neupane, AR Aldous, JA Kritzer
Journal of inorganic biochemistry 139, 65-76, 2014
552014
Macrocyclization of the ATCUN motif controls metal binding and catalysis
KP Neupane, AR Aldous, JA Kritzer
Inorganic chemistry 52 (5), 2729-2735, 2013
482013
Peptide bicycles that inhibit the Grb2 SH2 domain
JS Quartararo, P Wu, JA Kritzer
ChemBioChem 13 (10), 1490-1496, 2012
482012
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