Helical β-peptide inhibitors of the p53-hDM2 interaction JA Kritzer, JD Lear, ME Hodsdon, A Schepartz Journal of the American Chemical Society 126 (31), 9468-9469, 2004 | 390 | 2004 |
Getting in shape: controlling peptide bioactivity and bioavailability using conformational constraints JE Bock, J Gavenonis, JA Kritzer ACS chemical biology 8 (3), 488-499, 2013 | 246 | 2013 |
β-Peptides as inhibitors of protein–protein interactions JA Kritzer, OM Stephens, DA Guarracino, SK Reznik, A Schepartz Bioorganic & medicinal chemistry 13 (1), 11-16, 2005 | 236 | 2005 |
Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models LJ Su, PK Auluck, TF Outeiro, E Yeger-Lotem, JA Kritzer, DF Tardiff, ... Disease models & mechanisms 3 (3-4), 194-208, 2010 | 226 | 2010 |
Comprehensive analysis of loops at protein-protein interfaces for macrocycle design J Gavenonis, BA Sheneman, TR Siegert, MR Eshelman, JA Kritzer Nature chemical biology 10 (9), 716-722, 2014 | 223 | 2014 |
Rapid selection of cyclic peptides that reduce α-synuclein toxicity in yeast and animal models JA Kritzer, S Hamamichi, JM McCaffery, S Santagata, TA Naumann, ... Nature chemical biology 5 (9), 655-663, 2009 | 177 | 2009 |
Cell penetration profiling using the chloroalkane penetration assay L Peraro, KL Deprey, MK Moser, Z Zou, HL Ball, B Levine, JA Kritzer Journal of the American Chemical Society 140 (36), 11360-11369, 2018 | 149 | 2018 |
Diversity-oriented stapling yields intrinsically cell-penetrant inducers of autophagy L Peraro, Z Zou, KM Makwana, AE Cummings, HL Ball, H Yu, YS Lin, ... Journal of the American Chemical Society 139 (23), 7792-7802, 2017 | 147 | 2017 |
Emerging methods and design principles for cell‐penetrant peptides L Peraro, JA Kritzer Angewandte Chemie International Edition 57 (37), 11868-11881, 2018 | 145 | 2018 |
Relationship between Side Chain Structure and 14-Helix Stability of β3-Peptides in Water JA Kritzer, J Tirado-Rives, SA Hart, JD Lear, WL Jorgensen, A Schepartz Journal of the American Chemical Society 127 (1), 167-178, 2005 | 137 | 2005 |
Miniature protein inhibitors of the p53–hDM2 interaction JA Kritzer, R Zutshi, M Cheah, FA Ran, R Webman, TM Wongjirad, ... ChemBioChem 7 (1), 29-31, 2006 | 109 | 2006 |
Solution structure of a β-peptide ligand for hDM2 JA Kritzer, ME Hodsdon, A Schepartz Journal of the American Chemical Society 127 (12), 4118-4119, 2005 | 99 | 2005 |
A rapid library screen for tailoring β-peptide structure and function JA Kritzer, NW Luedtke, EA Harker, A Schepartz Journal of the American Chemical Society 127 (42), 14584-14585, 2005 | 85 | 2005 |
Trapped! A critical evaluation of methods for measuring total cellular uptake versus cytosolic localization K Deprey, L Becker, J Kritzer, A Plückthun Bioconjugate chemistry 30 (4), 1006-1027, 2019 | 78 | 2019 |
Analysis of loops that mediate protein–protein interactions and translation into submicromolar inhibitors TR Siegert, MJ Bird, KM Makwana, JA Kritzer Journal of the American Chemical Society 138 (39), 12876-12884, 2016 | 68 | 2016 |
A critical analysis of methods used to investigate the cellular uptake and subcellular localization of RNA therapeutics K Deprey, N Batistatou, JA Kritzer Nucleic acids research 48 (14), 7623-7639, 2020 | 63 | 2020 |
Conformational restriction of peptides using dithiol bis-alkylation L Peraro, TR Siegert, JA Kritzer Methods in enzymology 580, 303-332, 2016 | 62 | 2016 |
Metal-binding and redox properties of substituted linear and cyclic ATCUN motifs KP Neupane, AR Aldous, JA Kritzer Journal of inorganic biochemistry 139, 65-76, 2014 | 55 | 2014 |
Macrocyclization of the ATCUN motif controls metal binding and catalysis KP Neupane, AR Aldous, JA Kritzer Inorganic chemistry 52 (5), 2729-2735, 2013 | 48 | 2013 |
Peptide bicycles that inhibit the Grb2 SH2 domain JS Quartararo, P Wu, JA Kritzer ChemBioChem 13 (10), 1490-1496, 2012 | 48 | 2012 |