Metabolic competition in the tumor microenvironment is a driver of cancer progression CH Chang, J Qiu, D O’Sullivan, MD Buck, T Noguchi, JD Curtis, Q Chen, ... Cell 162 (6), 1229-1241, 2015 | 2920 | 2015 |
Posttranscriptional control of T cell effector function by aerobic glycolysis CH Chang, JD Curtis, LB Maggi, B Faubert, AV Villarino, D O’Sullivan, ... Cell 153 (6), 1239-1251, 2013 | 2296 | 2013 |
Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development GJW van der Windt, B Everts, CH Chang, JD Curtis, TC Freitas, E Amiel, ... Immunity 36 (1), 68-78, 2012 | 1612 | 2012 |
Fueling immunity: insights into metabolism and lymphocyte function EL Pearce, MC Poffenberger, CH Chang, RG Jones Science 342 (6155), 1242454, 2013 | 1447 | 2013 |
Mitochondrial dynamics controls T cell fate through metabolic programming MD Buck, D O’Sullivan, RIK Geltink, JD Curtis, CH Chang, DE Sanin, ... Cell 166 (1), 63-76, 2016 | 1352 | 2016 |
TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation B Everts, E Amiel, SCC Huang, AM Smith, CH Chang, WY Lam, ... Nature immunology 15 (4), 323-332, 2014 | 1149 | 2014 |
Memory CD8+ T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development D O’Sullivan, GJW van der Windt, SCC Huang, JD Curtis, CH Chang, ... Immunity 41 (1), 75-88, 2014 | 841 | 2014 |
CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability GJW Van Der Windt, D O’Sullivan, B Everts, SCC Huang, MD Buck, ... Proceedings of the National Academy of Sciences 110 (35), 14336-14341, 2013 | 578 | 2013 |
Emerging concepts of T cell metabolism as a target of immunotherapy CH Chang, EL Pearce Nature immunology 17 (4), 364-368, 2016 | 366 | 2016 |
Type 1 interferons induce changes in core metabolism that are critical for immune function D Wu, DE Sanin, B Everts, Q Chen, J Qiu, MD Buck, A Patterson, ... Immunity 44 (6), 1325-1336, 2016 | 320 | 2016 |
Acetate promotes T cell effector function during glucose restriction J Qiu, M Villa, DE Sanin, MD Buck, D O’Sullivan, R Ching, M Matsushita, ... Cell reports 27 (7), 2063-2074. e5, 2019 | 285 | 2019 |
Measuring bioenergetics in T cells using a seahorse extracellular flux analyzer GJW Van der Windt, CH Chang, EL Pearce Current protocols in immunology 113 (1), 3.16 B. 1-3.16 B. 14, 2016 | 245 | 2016 |
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance S Tenzer, E Wee, A Burgevin, G Stewart-Jones, L Friis, K Lamberth, ... Nature immunology 10 (6), 636-646, 2009 | 230 | 2009 |
Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment Z Gong, Q Li, J Shi, J Wei, P Li, CH Chang, LD Shultz, G Ren Immunity 55 (8), 1483-1500. e9, 2022 | 116 | 2022 |
APOBEC3G-induced hypermutation of human immunodeficiency virus type-1 is typically a discrete “all or nothing” phenomenon AE Armitage, K Deforche, C Chang, E Wee, B Kramer, JJ Welch, ... PLoS genetics 8 (3), e1002550, 2012 | 111 | 2012 |
Interleukin-17 drives interstitial entrapment of tissue lipoproteins in experimental psoriasis LH Huang, BH Zinselmeyer, CH Chang, BT Saunders, A Elvington, ... Cell metabolism 29 (2), 475-487. e7, 2019 | 72 | 2019 |
Targeting metabolism to reverse T‐cell exhaustion in chronic viral infections JD Sears, KJ Waldron, J Wei, CH Chang Immunology 162 (2), 135-144, 2021 | 32 | 2021 |
Remodeling of chromatin structure within the promoter is important for bmp-2-induced fgfr3 expression F Sun, Q Chen, S Yang, Q Pan, J Ma, Y Wan, CH Chang, A Hong Nucleic acids research 37 (12), 3897-3911, 2009 | 30 | 2009 |
Tonic TCR signaling inversely regulates the basal metabolism of CD4+ T cells AAV Milam, JM Bartleson, MD Buck, CH Chang, A Sergushichev, ... ImmunoHorizons 4 (8), 485-497, 2020 | 22 | 2020 |
Providing a helping hand: Metabolic regulation of T follicular helper cells and their association with disease CL Mayberry, NA Logan, JJ Wilson, CH Chang Frontiers in Immunology 13, 864949, 2022 | 9 | 2022 |