Maturation pathway from germline to broad HIV-1 neutralizer of a CD4-mimic antibody M Bonsignori, T Zhou, Z Sheng, L Chen, F Gao, MG Joyce, G Ozorowski, ... Cell 165 (2), 449-463, 2016 | 338 | 2016 |
Staged induction of HIV-1 glycan–dependent broadly neutralizing antibodies M Bonsignori, EF Kreider, D Fera, RR Meyerhoff, T Bradley, K Wiehe, ... Science translational medicine 9 (381), eaai7514, 2017 | 206 | 2017 |
SR proteins control a complex network of RNA-processing events T Bradley, ME Cook, M Blanchette Rna 21 (1), 75-92, 2015 | 164 | 2015 |
Potent and broad HIV-neutralizing antibodies in memory B cells and plasma LTD Williams, G Ofek, S Schätzle, JR McDaniel, X Lu, NI Nicely, L Wu, ... Science immunology 2 (7), eaal2200, 2017 | 155 | 2017 |
Antibody responses after a single dose of SARS-CoV-2 mRNA vaccine T Bradley, E Grundberg, R Selvarangan, C LeMaster, E Fraley, ... New England Journal of Medicine 384 (20), 1959-1961, 2021 | 154 | 2021 |
Targeted selection of HIV-specific antibody mutations by engineering B cell maturation KO Saunders, K Wiehe, M Tian, P Acharya, T Bradley, SM Alam, EP Go, ... Science 366 (6470), eaay7199, 2019 | 150 | 2019 |
Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge T Bradley, J Pollara, S Santra, N Vandergrift, S Pittala, C Bailey-Kellogg, ... Nature communications 8 (1), 15711, 2017 | 145 | 2017 |
Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV ME Ackerman, J Das, S Pittala, T Broge, C Linde, TJ Suscovich, EP Brown, ... Nature medicine 24 (10), 1590-1598, 2018 | 138 | 2018 |
Functional relevance of improbable antibody mutations for HIV broadly neutralizing antibody development K Wiehe, T Bradley, RR Meyerhoff, C Hart, WB Williams, D Easterhoff, ... Cell host & microbe 23 (6), 759-765. e6, 2018 | 127 | 2018 |
Two new and distinct roles for Drosophila Argonaute-2 in the nucleus: alternative pre-mRNA splicing and transcriptional repression JM Taliaferro, JL Aspden, T Bradley, D Marwha, M Blanchette, DC Rio Genes & development 27 (4), 378-389, 2013 | 123 | 2013 |
Initiation of immune tolerance–controlled HIV gp41 neutralizing B cell lineages R Zhang, L Verkoczy, K Wiehe, S Munir Alam, NI Nicely, S Santra, ... Science translational medicine 8 (336), 336ra62-336ra62, 2016 | 109 | 2016 |
Single-cell analysis of quiescent HIV infection reveals host transcriptional profiles that regulate proviral latency T Bradley, G Ferrari, BF Haynes, DM Margolis, EP Browne Cell reports 25 (1), 107-117. e3, 2018 | 104 | 2018 |
Single cell analysis reveals distinct immune landscapes in transplant and primary sarcomas that determine response or resistance to immunotherapy AJ Wisdom, YM Mowery, CS Hong, JE Himes, BY Nabet, X Qin, D Zhang, ... Nature communications 11 (1), 6410, 2020 | 90 | 2020 |
RAB11FIP5 expression and altered natural killer cell function are associated with induction of HIV broadly neutralizing antibody responses T Bradley, D Peppa, I Pedroza-Pacheco, D Li, DW Cain, R Henao, ... Cell 175 (2), 387-399. e17, 2018 | 87 | 2018 |
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies WB Williams, RR Meyerhoff, RJ Edwards, H Li, K Manne, NI Nicely, ... Cell 184 (11), 2955-2972. e25, 2021 | 85 | 2021 |
Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations WB Williams, J Zhang, C Jiang, NI Nicely, D Fera, K Luo, MA Moody, ... Nature communications 8 (1), 1732, 2017 | 85 | 2017 |
Humoral immune responses during SARS-CoV-2 mRNA vaccine administration in seropositive and seronegative individuals E Fraley, C LeMaster, E Geanes, D Banerjee, S Khanal, E Grundberg, ... BMC medicine 19, 1-12, 2021 | 67 | 2021 |
Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved K Wiehe, D Easterhoff, K Luo, NI Nicely, T Bradley, FH Jaeger, ... Immunity 41 (6), 909-918, 2014 | 66 | 2014 |
Structural constraints of vaccine-induced tier-2 autologous HIV neutralizing antibodies targeting the receptor-binding site T Bradley, D Fera, J Bhiman, L Eslamizar, X Lu, K Anasti, R Zhang, ... Cell reports 14 (1), 43-54, 2016 | 60 | 2016 |
Targeting natural killer cells for improved immunity and control of the adaptive immune response S Pierce, ES Geanes, T Bradley Frontiers in Cellular and Infection Microbiology 10, 231, 2020 | 54 | 2020 |