Παρακολούθηση
Rajendra Karki
Rajendra Karki
Seoul National University
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα snu.ac.kr
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Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases
SM Man, R Karki, TD Kanneganti
Immunological reviews 277 (1), 61-75, 2017
15612017
Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes
R Karki, BR Sharma, S Tuladhar, EP Williams, L Zalduondo, P Samir, ...
Cell 184 (1), 149-168. e17, 2021
14192021
ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways
T Kuriakose, SM Man, RK Subbarao Malireddi, R Karki, S Kesavardhana, ...
Science immunology 1 (2), aag2045-aag2045, 2016
6612016
Diverging inflammasome signals in tumorigenesis and potential targeting
R Karki, TD Kanneganti
Nature Reviews Cancer 19 (4), 197-214, 2019
5632019
TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines
M Zheng, R Karki, EP Williams, D Yang, E Fitzpatrick, P Vogel, ...
Nature immunology 22 (7), 829-838, 2021
5562021
AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence
SJ Lee, R Karki, Y Wang, LN Nguyen, RC Kalathur, TD Kanneganti
Nature 597 (7876), 415-419, 2021
4042021
Caspase-6 is a key regulator of innate immunity, inflammasome activation, and host defense
M Zheng, R Karki, P Vogel, TD Kanneganti
Cell 181 (3), 674-687. e13, 2020
3802020
Inflammasomes and cancer
R Karki, SM Man, TD Kanneganti
Cancer immunology research 5 (2), 94-99, 2017
3732017
The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection
SM Man, R Karki, RKS Malireddi, G Neale, P Vogel, M Yamamoto, ...
Nature immunology 16 (5), 467-475, 2015
3732015
Identification of the PANoptosome: a molecular platform triggering pyroptosis, apoptosis, and necroptosis (PANoptosis)
S Christgen, M Zheng, S Kesavardhana, R Karki, RKS Malireddi, ...
Frontiers in cellular and infection microbiology 10, 237, 2020
3692020
AIM2 inflammasome in infection, cancer, and autoimmunity: Role in DNA sensing, inflammation, and innate immunity
SM Man, R Karki, TD Kanneganti
European journal of immunology 46 (2), 269-280, 2016
3662016
DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome
P Samir, S Kesavardhana, DM Patmore, S Gingras, RKS Malireddi, ...
Nature 573 (7775), 590-594, 2019
3622019
Critical role for the DNA sensor AIM2 in stem cell proliferation and cancer
SM Man, Q Zhu, L Zhu, Z Liu, R Karki, A Malik, D Sharma, L Li, ...
Cell 162 (1), 45-58, 2015
3402015
IRGB10 liberates bacterial ligands for sensing by the AIM2 and caspase-11-NLRP3 inflammasomes
SM Man, R Karki, M Sasai, DE Place, S Kesavardhana, J Temirov, ...
Cell 167 (2), 382-396. e17, 2016
3062016
The ‘cytokine storm’: molecular mechanisms and therapeutic prospects
R Karki, TD Kanneganti
Trends in immunology 42 (8), 681-705, 2021
2892021
Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection
R Karki, SM Man, RKS Malireddi, P Gurung, P Vogel, M Lamkanfi, ...
Cell host & microbe 17 (3), 357-368, 2015
2812015
ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis
R Karki, B Sundaram, BR Sharma, SJ Lee, RKS Malireddi, LN Nguyen, ...
Cell reports 37 (3), 2021
2502021
Role of AIM2 inflammasome in inflammatory diseases, cancer and infection
BR Sharma, R Karki, TD Kanneganti
European journal of immunology 49 (11), 1998-2011, 2019
2482019
Interferon regulatory factor 1 regulates PANoptosis to prevent colorectal cancer
R Karki, BR Sharma, B Banoth, RKS Malireddi, P Samir, S Tuladhar, ...
JCI insight 5 (12), 2020
2002020
Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection
M Zheng, EP Williams, RKS Malireddi, R Karki, B Banoth, A Burton, ...
Journal of Biological Chemistry 295 (41), 14040-14052, 2020
1902020
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