| DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells A De Magis, SG Manzo, M Russo, J Marinello, R Morigi, O Sordet, ... Proceedings of the National Academy of Sciences 116 (3), 816-825, 2019 | 294 | 2019 |
| Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance R Schep, EK Brinkman, C Leemans, X Vergara, RH van der Weide, ... Molecular cell 81 (10), 2216-2230. e10, 2021 | 168 | 2021 |
| DNA Topoisomerase I differentially modulates R-loops across the human genome SG Manzo, SR Hartono, LA Sanz, J Marinello, S De Biasi, A Cossarizza, ... Genome biology 19, 1-18, 2018 | 163 | 2018 |
| Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II SG Manzo, ZL Zhou, YQ Wang, J Marinello, JX He, YC Li, J Ding, ... Cancer Research 72 (20), 5363-5373, 2012 | 118 | 2012 |
| The natural inhibitor of DNA topoisomerase I, camptothecin, modulates HIF-1α activity by changing miR expression patterns in human cancer cells D Bertozzi, J Marinello, SG Manzo, F Fornari, L Gramantieri, G Capranico Molecular cancer therapeutics 13 (1), 239-248, 2014 | 83 | 2014 |
| Antisense transcripts enhanced by camptothecin at divergent CpG-island promoters associated with bursts of topoisomerase I-DNA cleavage complex and R-loop formation J Marinello, G Chillemi, S Bueno, SG Manzo, G Capranico Nucleic acids research 41 (22), 10110-10123, 2013 | 80 | 2013 |
| Lamina-associated domains: Tethers and looseners SG Manzo, L Dauban, B van Steensel Current Opinion in Cell Biology 74, 80-87, 2022 | 53 | 2022 |
| Novel DNA topoisomerase IIα inhibitors from combined ligand-and structure-based virtual screening MN Drwal, J Marinello, SG Manzo, LPG Wakelin, G Capranico, R Griffith PLoS One 9 (12), e114904, 2014 | 46 | 2014 |
| CTCF and cohesin promote focal detachment of DNA from the nuclear lamina T van Schaik, NQ Liu, SG Manzo, D Peric-Hupkes, E de Wit, ... Genome Biology 23 (1), 185, 2022 | 18 | 2022 |
| Dynamic chromosomal interactions and control of heterochromatin positioning by Ki‐67 T van Schaik, SG Manzo, AE Vouzas, NQ Liu, H Teunissen, E de Wit, ... EMBO reports 23 (12), e55782, 2022 | 15 | 2022 |
| Perturbations in 3D genome organization can promote acquired drug resistance AG Manjón, SG Manzo, S Prekovic, L Potgeter, T van Schaik, NQ Liu, ... Cell Reports 42 (10), 2023 | 13 | 2023 |
| Optimisation of TP53 reporters by systematic dissection of synthetic TP53 response elements M Trauernicht, C Rastogi, SG Manzo, HJ Bussemaker, B van Steensel Nucleic Acids Research 51 (18), 9690-9702, 2023 | 7 | 2023 |
| Chromatin context-dependent effects of epigenetic drugs on CRISPR-Cas9 editing R Schep, M Trauernicht, X Vergara, A Friskes, B Morris, S Gregoricchio, ... Nucleic Acids Research 52 (15), 8815-8832, 2024 | 4 | 2024 |
| Acute multi-level response to defective de novo chromatin assembly in S-phase J Dreyer, G Ricci, J van den Berg, V Bhardwaj, J Funk, C Armstrong, ... Molecular cell 84 (24), 4711-4728. e10, 2024 | 3 | 2024 |
| Genome-wide mapping and microscopy visualization of protein–DNA interactions by pA-DamID T van Schaik, SG Manzo, B van Steensel Chromatin: Methods and Protocols, 215-229, 2022 | 3 | 2022 |
| CTCF and cohesin promote focal detachment of DNA from the nuclear lamina T van Schaik, NQ Liu, SG Manzo, D Peric-Hupkes, E de Wit, ... bioRxiv, 2021.09. 13.460079, 2021 | 2 | 2021 |
| Antisense transcripts and R-loops caused by DNA topoisomerase I inhibition by camptothecin at human active CpG island promoters. J Marinello, G Chillemi, S Bueno, SG Manzo, G Capranico Cancer Research 73 (8_Supplement), 637-637, 2013 | 2 | 2013 |
| Phosphorylated lamins in euchromatin: new clues to progeria SG Manzo, B van Steensel Developmental Cell 52 (6), 676-678, 2020 | 1 | 2020 |
| Chromatin protein complexes involved in gene repression in lamina-associated domains SG Manzo, A Mazouzi, C Leemans, T van Schaik, N Neyazi, ... The EMBO Journal 43 (21), 5260-5287, 2024 | | 2024 |
| Coordinated control of genome-nuclear lamina interactions by Topoisomerase 2B and Lamin B receptor SG Manzo, T van Schaik, M de Haas, J Breda, M Magnitov, E de Wit, ... bioRxiv, 2024.10. 01.616012, 2024 | | 2024 |
