| Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II H Lu, D Yu, AS Hansen, S Ganguly, R Liu, A Heckert, X Darzacq, Q Zhou Nature 558 (7709), 318-323, 2018 | 549 | 2018 |
| Liquid–liquid phase separation in human health and diseases B Wang, L Zhang, T Dai, Z Qin, H Lu, L Zhang, F Zhou Signal transduction and targeted therapy 6 (1), 290, 2021 | 470 | 2021 |
| Phase separation of TAZ compartmentalizes the transcription machinery to promote gene expression Y Lu, T Wu, O Gutman, H Lu, Q Zhou, YI Henis, K Luo Nature cell biology 22 (4), 453-464, 2020 | 293 | 2020 |
| Targeting liquid–liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity S Wang, T Dai, Z Qin, T Pan, F Chu, L Lou, L Zhang, B Yang, H Huang, ... Nature Cell Biology 23 (7), 718-732, 2021 | 224 | 2021 |
| Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism H Lu, Y Xue, GK Yu, C Arias, J Lin, S Fong, M Faure, B Weisburd, X Ji, ... elife 4, e06535, 2015 | 152 | 2015 |
| HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold S Chou, H Upton, K Bao, U Schulze-Gahmen, AJ Samelson, N He, ... Proceedings of the National Academy of Sciences 110 (2), E123-E131, 2013 | 109 | 2013 |
| Post-translational modifications in liquid-liquid phase separation: a comprehensive review J Li, M Zhang, W Ma, B Yang, H Lu, F Zhou, L Zhang Molecular biomedicine 3 (1), 13, 2022 | 102 | 2022 |
| LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis X Ji, H Lu, Q Zhou, K Luo Elife 3, e02907, 2014 | 95 | 2014 |
| AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation H Lu, Z Li, Y Xue, U Schulze-Gahmen, JR Johnson, NJ Krogan, T Alber, ... Proceedings of the National Academy of Sciences 111 (1), E15-E24, 2014 | 84 | 2014 |
| A subcellular map of the human kinome H Zhang, X Cao, M Tang, G Zhong, Y Si, H Li, F Zhu, Q Liao, L Li, J Zhao, ... Elife 10, e64943, 2021 | 76 | 2021 |
| Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat: AFF4: P-TEFb: TAR complex U Schulze-Gahmen, I Echeverria, G Stjepanovic, Y Bai, H Lu, ... Elife 5, e15910, 2016 | 64 | 2016 |
| AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter U Schulze-Gahmen, H Lu, Q Zhou, T Alber Elife 3, e02375, 2014 | 63 | 2014 |
| Deactylation by SIRT1 enables liquid–liquid phase separation of IRF3/IRF7 in innate antiviral immunity Z Qin, X Fang, W Sun, Z Ma, T Dai, S Wang, Z Zong, H Huang, H Ru, H Lu, ... Nature immunology 23 (8), 1193-1207, 2022 | 60 | 2022 |
| Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription H Lu, Z Li, W Zhang, U Schulze-Gahmen, Y Xue, Q Zhou Nucleic Acids Research 43 (12), 5868-5879, 2015 | 60 | 2015 |
| Poly (ADP-ribosylation) of P-TEFb by PARP1 disrupts phase separation to inhibit global transcription after DNA damage H Fu, R Liu, Z Jia, R Li, F Zhu, W Zhu, Y Shao, Y Jin, Y Xue, J Huang, ... Nature cell biology 24 (4), 513-525, 2022 | 53 | 2022 |
| Viral–host interactions that control HIV-1 transcriptional elongation H Lu, Z Li, Y Xue, Q Zhou Chemical reviews 113 (11), 8567-8582, 2013 | 51 | 2013 |
| R-loop-dependent promoter-proximal termination ensures genome stability C Xu, C Li, J Chen, Y Xiong, Z Qiao, P Fan, C Li, S Ma, J Liu, A Song, ... Nature 621 (7979), 610-619, 2023 | 45 | 2023 |
| Shrimp STAT was hijacked by white spot syndrome virus immediate-early protein IE1 involved in modulation of viral genes D Yao, L Ruan, H Lu, H Shi, X Xu Fish & Shellfish Immunology 59, 268-275, 2016 | 41 | 2016 |
| A minor subset of super elongation complexes plays a predominant role in reversing HIV-1 latency Z Li, H Lu, Q Zhou Molecular and Cellular Biology 36 (7), 1194-1205, 2016 | 27 | 2016 |
| An immediate-early protein of white spot syndrome virus modulates the phosphorylation of focal adhesion kinase of shrimp H Lu, L Ruan, X Xu Virology 419 (2), 84-89, 2011 | 26 | 2011 |
