Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4 OS Qureshi, Y Zheng, K Nakamura, K Attridge, C Manzotti, EM Schmidt, ... Science 332 (6029), 600-603, 2011 | 2230 | 2011 |
1, 25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3 LE Jeffery, F Burke, M Mura, Y Zheng, OS Qureshi, M Hewison, ... The journal of immunology 183 (9), 5458-5467, 2009 | 1011 | 2009 |
Evidence for functional P2X4/P2X7 heteromeric receptors C Guo, M Masin, OS Qureshi, RD Murrell-Lagnado Molecular pharmacology 72 (6), 1447-1456, 2007 | 326 | 2007 |
Monocyte subsets in human liver disease show distinct phenotypic and functional characteristics E Liaskou, HW Zimmermann, KK Li, YH Oo, S Suresh, Z Stamataki, ... Hepatology 57 (1), 385-398, 2013 | 285 | 2013 |
Availability of 25-hydroxyvitamin D3 to APCs controls the balance between regulatory and inflammatory T cell responses LE Jeffery, AM Wood, OS Qureshi, TZ Hou, D Gardner, Z Briggs, S Kaur, ... The Journal of Immunology 189 (11), 5155-5164, 2012 | 249 | 2012 |
Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis OS Qureshi, A Paramasivam, JCH Yu, RD Murrell-Lagnado Journal of cell science 120 (21), 3838-3849, 2007 | 247 | 2007 |
Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity EM Schmidt, CJ Wang, GA Ryan, LE Clough, OS Qureshi, M Goodall, ... The Journal of Immunology 182 (1), 274-282, 2009 | 202 | 2009 |
Constitutive clathrin-mediated endocytosis of CTLA-4 persists during T cell activation OS Qureshi, S Kaur, TZ Hou, LE Jeffery, NS Poulter, Z Briggs, R Kenefeck, ... Journal of Biological Chemistry 287 (12), 9429-9440, 2012 | 201 | 2012 |
Fc gamma receptors and their role in antigen uptake, presentation, and T cell activation F Junker, J Gordon, O Qureshi Frontiers in Immunology 11, 547589, 2020 | 194 | 2020 |
ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages D Biswas, OS Qureshi, WY Lee, JE Croudace, M Mura, DA Lammas BMC immunology 9, 1-10, 2008 | 189 | 2008 |
A transendocytosis model of CTLA-4 function predicts its suppressive behavior on regulatory T cells TZ Hou, OS Qureshi, CJ Wang, J Baker, SP Young, LSK Walker, ... The Journal of Immunology 194 (5), 2148-2159, 2015 | 147 | 2015 |
Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation A Kennedy, E Waters, B Rowshanravan, C Hinze, C Williams, D Janman, ... Nature immunology 23 (9), 1365-1378, 2022 | 142 | 2022 |
Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG … B Smith, A Kiessling, R Lledo-Garcia, KL Dixon, L Christodoulou, ... MAbs 10 (7), 1111-1130, 2018 | 119 | 2018 |
Acquisition of suppressive function by activated human CD4+ CD25− T cells is associated with the expression of CTLA-4 not FoxP3 Y Zheng, CN Manzotti, F Burke, L Dussably, O Qureshi, LSK Walker, ... The Journal of Immunology 181 (3), 1683-1691, 2008 | 117 | 2008 |
Non-canonical YXXGΦ endocytic motifs: recognition by AP2 and preferential utilization in P2X4 receptors SJ Royle, OS Qureshi, LK Bobanovic, PR Evans, DJ Owen, ... Journal of Cell Science 118 (14), 3073-3080, 2005 | 112 | 2005 |
Cutting edge: cell-extrinsic immune regulation by CTLA-4 expressed on conventional T cells CJ Wang, R Kenefeck, L Wardzinski, K Attridge, C Manzotti, EM Schmidt, ... The Journal of Immunology 189 (3), 1118-1122, 2012 | 104 | 2012 |
An uncharged region within the N terminus of the P2X6 receptor inhibits its assembly and exit from the endoplasmic reticulum SJ Ormond, NP Barrera, OS Qureshi, RM Henderson, JM Edwardson, ... Molecular pharmacology 69 (5), 1692-1700, 2006 | 76 | 2006 |
A distinct subset of podoplanin (gp38) expressing F4/80+ macrophages mediate phagocytosis and are induced following zymosan peritonitis TZ Hou, J Bystrom, JP Sherlock, O Qureshi, SM Parnell, G Anderson, ... FEBS letters 584 (18), 3955-3961, 2010 | 68 | 2010 |
Vitamin D antagonises the suppressive effect of inflammatory cytokines on CTLA-4 expression and regulatory function LE Jeffery, OS Qureshi, D Gardner, TZ Hou, Z Briggs, B Soskic, J Baker, ... PloS one 10 (7), e0131539, 2015 | 67 | 2015 |
Fc-engineered antibodies with immune effector functions completely abolished I Wilkinson, S Anderson, J Fry, LA Julien, D Neville, O Qureshi, G Watts, ... PLoS One 16 (12), e0260954, 2021 | 66 | 2021 |