Mitochondrial dysfunction in Parkinson’s disease–a key disease hallmark with therapeutic potential MT Henrich, WH Oertel, DJ Surmeier, FF Geibl Molecular neurodegeneration 18 (1), 83, 2023 | 92 | 2023 |
Determinants of seeding and spreading of α-synuclein pathology in the brain MT Henrich, FF Geibl, H Lakshminarasimhan, A Stegmann, BI Giasson, ... Science Advances 6 (46), eabc2487, 2020 | 82 | 2020 |
A53T-α-synuclein overexpression in murine locus coeruleus induces Parkinson’s disease-like pathology in neurons and glia MT Henrich, FF Geibl, B Lee, WH Chiu, JB Koprich, JM Brotchie, ... Acta neuropathologica communications 6, 1-19, 2018 | 72 | 2018 |
The locus coeruleus: Another vulnerability target in Parkinson's disease WH Oertel, MT Henrich, A Janzen, FF Geibl Movement Disorders 34 (10), 1423-1429, 2019 | 41 | 2019 |
Mesencephalic and extramesencephalic dopaminergic systems in Parkinson’s disease FF Geibl, MT Henrich, WH Oertel Journal of Neural Transmission 126, 377-396, 2019 | 37 | 2019 |
The roles of connectivity and neuronal phenotype in determining the pattern of α-synuclein pathology in Parkinson's disease MX Henderson, MT Henrich, FF Geibl, WH Oertel, P Brundin, DJ Surmeier Neurobiology of disease 168, 105687, 2022 | 27 | 2022 |
Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease LA Matschke, MA Komadowski, A Stöhr, B Lee, MT Henrich, M Griesbach, ... Scientific Reports 12 (1), 3180, 2022 | 18 | 2022 |
α-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinson’s disease FF Geibl, MT Henrich, Z Xie, E Zampese, J Ueda, T Tkatch, DL Wokosin, ... Molecular neurodegeneration 19 (1), 69, 2024 | 14 | 2024 |
Progressive olfactory impairment and cardiac sympathetic denervation in REM sleep behavior disorder A Janzen, D Vadasz, J Booij, M Luster, D Librizzi, MT Henrich, ... Journal of Parkinson's Disease 12 (6), 1921-1935, 2022 | 14 | 2022 |
Acetyl-DL-leucine in two individuals with REM sleep behavior disorder improves symptoms, reverses loss of striatal dopamine-transporter binding and stabilizes … WH Oertel, A Janzen, MT Henrich, FF Geibl, E Sittig, SK Meles, G Carli, ... Nature communications 15 (1), 7619, 2024 | 4 | 2024 |
Efficient characterization of multiple binding sites of small molecule imaging ligands on amyloid-beta, 4-repeat/full-length tau and alpha-synuclein J Sobek, J Li, BF Combes, JA Gerez, PK Nilsson, MT Henrich, FF Geibl, ... bioRxiv, 2023.03. 12.531651, 2023 | 3 | 2023 |
Efficient characterization of multiple binding sites of small molecule imaging ligands on amyloid-beta, tau and alpha-synuclein J Sobek, J Li, BF Combes, JA Gerez, MT Henrich, FF Geibl, PR Nilsson, ... European journal of nuclear medicine and molecular imaging 51 (13), 3960-3977, 2024 | 2 | 2024 |
Development and Evaluation of [18F]FS9, Novel PET tracer for a-Synucleinopathies in PFF mouse model of Parkinson's Disease BH Yousefi, B Uzuegbunam, S Bagheri, W Paslawski, J Li, A Rosenau, ... EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 51, S402-S402, 2024 | | 2024 |
PET/CT of α-Synucleinopathies in Parkinson's Disease Mouse Model with F-18-FS9, a Novel Selective Radiotracer for α-Synuclein Fibrils S Bagheri, B Uzuegbunam, D Librizzi, G Kotipalli, E Nasiri, F Geibl, ... Nuklearmedizin-NuclearMedicine 63 (02), L04, 2024 | | 2024 |
DAB staining protocol for subsequent stereological cell counting MT Henrich, FF Geibl | | 2023 |
Proteinase K digestion MT Henrich, FF Geibl | | 2023 |
Perfusion and fixation of brain tissue for fresh frozen sections followed by immunofluorescence staining MT Henrich, FF Geibl | | 2023 |
The Locus coeruleus in Parkinson’s disease-from basic research to new translational perspectives MT Henrich Philipps-Universität Marburg, 2019 | | 2019 |
AAV-mediated human alpha synuclein overexpression in the locus coeruleus (LC) leads to a neuronal loss in the nucleus ambiguus of mouse B Lee, M Henrich, WH Chiu, L Matschke MOVEMENT DISORDERS 32, 2017 | | 2017 |
Targeted overexpression of A53T-alpha-synuclein induces progressive neurodegeneration and electrophysiological changes of noradrenergic locus coeruleus neurons-a preclinical … M Henrich, L Matschke, A Stoehr, WH Chiu, B Lee, F Geibl, J Koprich, ... MOVEMENT DISORDERS 32, 2017 | | 2017 |