| Design and evaluation of novel pH-sensitive chitosan nanoparticles for oral insulin delivery A Makhlof, Y Tozuka, H Takeuchi European journal of pharmaceutical sciences 42 (5), 445-451, 2011 | 342 | 2011 |
| pH-Sensitive nanospheres for colon-specific drug delivery in experimentally induced colitis rat model A Makhlof, Y Tozuka, H Takeuchi European Journal of Pharmaceutics and Biopharmaceutics 72 (1), 1-8, 2009 | 226 | 2009 |
| Modification of physicochemical and mechanical properties of shellac by partial hydrolysis S Limmatvapirat, C Limmatvapirat, M Luangtana-Anan, J Nunthanid, ... International journal of pharmaceutics 278 (1), 41-49, 2004 | 175 | 2004 |
| Design and evaluation of a liposomal delivery system targeting the posterior segment of the eye K Hironaka, Y Inokuchi, Y Tozuka, M Shimazawa, H Hara, H Takeuchi Journal of controlled release 136 (3), 247-253, 2009 | 159 | 2009 |
| A mucoadhesive nanoparticulate system for the simultaneous delivery of macromolecules and permeation enhancers to the intestinal mucosa A Makhlof, M Werle, Y Tozuka, H Takeuchi Journal of controlled release 149 (1), 81-88, 2011 | 153 | 2011 |
| Improvement of physicochemical properties of N-4472 part I formulation design by using self-microemulsifying system K Itoh, Y Tozuka, T Oguchi, K Yamamoto International journal of pharmaceutics 238 (1-2), 153-160, 2002 | 147 | 2002 |
| Nanoparticles of glycol chitosan and its thiolated derivative significantly improved the pulmonary delivery of calcitonin A Makhlof, M Werle, Y Tozuka, H Takeuchi International journal of pharmaceutics 397 (1-2), 92-95, 2010 | 139 | 2010 |
| Supercritical carbon dioxide processing of active pharmaceutical ingredients for polymorphic control and for complex formation K Moribe, Y Tozuka, K Yamamoto Advanced Drug Delivery Reviews 60 (3), 328-338, 2008 | 125 | 2008 |
| Nanoparticle formation of poorly water-soluble drugs from ternary ground mixtures with PVP and SDS K Itoh, A Pongpeerapat, Y Tozuka, T Oguchi, K Yamamoto Chemical and pharmaceutical bulletin 51 (2), 171-174, 2003 | 118 | 2003 |
| Liposomal diclofenac eye drop formulations targeting the retina: formulation stability improvement using surface modification of liposomes T Fujisawa, H Miyai, K Hironaka, T Tsukamoto, K Tahara, Y Tozuka, M Ito, ... International journal of pharmaceutics 436 (1-2), 564-567, 2012 | 109 | 2012 |
| In vitro and in vivo evaluation of WGA–carbopol modified liposomes as carriers for oral peptide delivery A Makhlof, S Fujimoto, Y Tozuka, H Takeuchi European journal of pharmaceutics and biopharmaceutics 77 (2), 216-224, 2011 | 108 | 2011 |
| Pulmonary delivery of elcatonin using surface-modified liposomes to improve systemic absorption: polyvinyl alcohol with a hydrophobic anchor and chitosan oligosaccharide as … M Murata, K Nakano, K Tahara, Y Tozuka, H Takeuchi European Journal of Pharmaceutics and Biopharmaceutics 80 (2), 340-346, 2012 | 95 | 2012 |
| Physicochemical properties affecting retinal drug/coumarin-6 delivery from nanocarrier systems via eyedrop administration Y Inokuchi, K Hironaka, T Fujisawa, Y Tozuka, K Tsuruma, M Shimazawa, ... Investigative ophthalmology & visual science 51 (6), 3162-3170, 2010 | 94 | 2010 |
| Retinal drug delivery using eyedrop preparations of poly-L-lysine-modified liposomes H Sasaki, K Karasawa, K Hironaka, K Tahara, Y Tozuka, H Takeuchi European Journal of Pharmaceutics and Biopharmaceutics 83 (3), 364-369, 2013 | 90 | 2013 |
| Formation of fine drug particles by cogrinding with cyclodextrins. I. The use of β-cyclodextrin anhydrate and hydrate A Wongmekiat, Y Tozuka, T Oguchi, K Yamamoto Pharmaceutical research 19, 1867-1872, 2002 | 86 | 2002 |
| Edaravone-loaded liposome eyedrops protect against light-induced retinal damage in mice H Shimazaki, K Hironaka, T Fujisawa, K Tsuruma, Y Tozuka, ... Investigative Ophthalmology & Visual Science 52 (10), 7289-7297, 2011 | 82 | 2011 |
| A novel method for measuring rigidity of submicron-size liposomes with atomic force microscopy K Nakano, Y Tozuka, H Yamamoto, Y Kawashima, H Takeuchi International journal of pharmaceutics 355 (1-2), 203-209, 2008 | 82 | 2008 |
| Formation mechanism of colloidal nanoparticles obtained from probucol/PVP/SDS ternary ground mixture A Pongpeerapat, C Wanawongthai, Y Tozuka, K Moribe, K Yamamoto International journal of pharmaceutics 352 (1-2), 309-316, 2008 | 82 | 2008 |
| Edaravone-loaded liposomes for retinal protection against oxidative stress-induced retinal damage K Hironaka, Y Inokuchi, T Fujisawa, H Shimazaki, M Akane, Y Tozuka, ... European Journal of Pharmaceutics and Biopharmaceutics 79 (1), 119-125, 2011 | 72 | 2011 |
| Mixed micelles of the antihistaminic cationic drug diphenhydramine hydrochloride with anionic and non-ionic surfactants show improved solubility, drug release and cytotoxicity … A Srivastava, H Uchiyama, Y Wada, Y Hatanaka, Y Shirakawa, K Kadota, ... Journal of Molecular liquids 277, 349-359, 2019 | 67 | 2019 |
