An intramolecular coupling approach to alkyl bioisosteres for the synthesis of multisubstituted bicycloalkyl boronates Y Yang, J Tsien, JME Hughes, BK Peters, RR Merchant, T Qin Nature chemistry 13 (10), 950-955, 2021 | 117 | 2021 |
Practical and Modular Construction of C(sp3)-Rich Alkyl Boron Compounds Y Yang, J Tsien, A Ben David, JME Hughes, RR Merchant, T Qin Journal of the American Chemical Society 143 (1), 471-480, 2020 | 86 | 2020 |
Building C(sp3)-rich complexity by combining cycloaddition and C–C cross-coupling reactions TG Chen, LM Barton, Y Lin, J Tsien, D Kossler, I Bastida, S Asai, C Bi, ... Nature 560 (7718), 350-354, 2018 | 79 | 2018 |
Sulfur (IV)‐Mediated Unsymmetrical Heterocycle Cross‐Couplings M Zhou, J Tsien, T Qin Angewandte Chemie International Edition 59 (19), 7372-7376, 2020 | 38 | 2020 |
Three-dimensional saturated C(sp3)-rich bioisosteres for benzene J Tsien, C Hu, RR Merchant, T Qin Nature Reviews Chemistry 8 (8), 605-627, 2024 | 37 | 2024 |
Alkyl sulfinates as cross-coupling partners for programmable and stereospecific installation of C(sp3) bioisosteres M Zhou, J Tsien, R Dykstra, JME Hughes, BK Peters, RR Merchant, ... Nature chemistry 15 (4), 550-559, 2023 | 18 | 2023 |
Programmable late-stage functionalization of bridge-substituted bicyclo [1.1. 1] pentane bis-boronates Y Yang, J Tsien, R Dykstra, SJ Chen, JB Wang, RR Merchant, ... Nature chemistry 16 (2), 285-293, 2024 | 16 | 2024 |
Characterization of the endogenous DAF-12 ligand and its use as an anthelmintic agent in Strongyloides stercoralis Z Wang, MC Cheong, J Tsien, H Deng, T Qin, JDC Stoltzfus, TG Jaleta, ... Elife 10, e73535, 2021 | 14 | 2021 |
A general three-component alkyl petasis boron–mannich reaction C Hu, J Tsien, SJ Chen, M Kong, RR Merchant, Y Kanda, T Qin Journal of the American Chemical Society 146 (31), 21769-21777, 2024 | 8 | 2024 |
Synthesis of multi-substituted bicycloalkyl boronates: An intramolecular coupling approach to alkyl bioisosteres Y Yang, J Tsien, J Hughes, B Peters, R Merchant, T Qin | 5 | 2021 |
Unsymmetrical heterocycle cross-couplings enabled by sulfur (IV) reagents M Zhou, J Tsien, T Qin Synlett 31 (20), 1962-1966, 2020 | 5 | 2020 |
Direct binding to sterols accelerates endoplasmic reticulum-associated degradation of HMG CoA reductase RA Faulkner, Y Yang, J Tsien, T Qin, RA DeBose-Boyd Proceedings of the National Academy of Sciences 121 (7), e2318822121, 2024 | 2 | 2024 |
Corrigendum to: Sulfur (IV)-Mediated Unsymmetrical Heterocycle Cross-Couplings (Angewandte Chemie International Edition,(2020), 59, 19,(7372-7376), 10.1002/anie. 201915425) M Zhou, J Tsien, T Qin Angewandte Chemie-International Edition 60 (11), 5601, 2021 | 1 | 2021 |
Structure-Based Discovery and Development of Highly Potent Dihydroorotate Dehydrogenase Inhibitors for Malaria Chemoprevention Z Nie, R Bonnert, J Tsien, X Deng, C Higgs, F El Mazouni, X Zhang, R Li, ... Journal of Medicinal Chemistry 68 (1), 590-637, 2024 | | 2024 |
Isosteric 3D Bicyclo [1.1. 1] Pentane (BCP) Core-Based Lipids for mRNA Delivery and CRISPR/Cas Gene Editing S Wu, Y Yang, X Lian, F Zhang, C Hu, J Tsien, Z Chen, Y Sun, A Vaidya, ... Journal of the American Chemical Society 146 (50), 34733-34742, 2024 | | 2024 |
A General Redox-Neutral Platform for Radical Cross-Coupling Á Péter, J Sun, J He, J Tsien, H Zhang, B Vokits, D Peters, M Mandler, ... | | 2024 |
Sulfur (IV)-Mediated Unsymmetrical Heterocycle Cross-Couplings (vol 17, pg 7372, 2020) M Zhou, J Tsien, T Qin ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 60 (11), 5601-5601, 2021 | | 2021 |
Berichtigung: Sulfur (IV)‐Mediated Unsymmetrical Heterocycle Cross‐Couplings. M Zhou, J Tsien, T Qin Angewandte Chemie 133 (11), 2021 | | 2021 |
S (IV)–Mediated Unsymmetrical Heterocycle Cross-Couplings M Zhou, J Tsien, T Qin | | 2019 |