Παρακολούθηση
Jet Tsien
Jet Tsien
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα scripps.edu
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Παρατίθεται από
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An intramolecular coupling approach to alkyl bioisosteres for the synthesis of multisubstituted bicycloalkyl boronates
Y Yang, J Tsien, JME Hughes, BK Peters, RR Merchant, T Qin
Nature chemistry 13 (10), 950-955, 2021
1172021
Practical and Modular Construction of C(sp3)-Rich Alkyl Boron Compounds
Y Yang, J Tsien, A Ben David, JME Hughes, RR Merchant, T Qin
Journal of the American Chemical Society 143 (1), 471-480, 2020
862020
Building C(sp3)-rich complexity by combining cycloaddition and C–C cross-coupling reactions
TG Chen, LM Barton, Y Lin, J Tsien, D Kossler, I Bastida, S Asai, C Bi, ...
Nature 560 (7718), 350-354, 2018
792018
Sulfur (IV)‐Mediated Unsymmetrical Heterocycle Cross‐Couplings
M Zhou, J Tsien, T Qin
Angewandte Chemie International Edition 59 (19), 7372-7376, 2020
382020
Three-dimensional saturated C(sp3)-rich bioisosteres for benzene
J Tsien, C Hu, RR Merchant, T Qin
Nature Reviews Chemistry 8 (8), 605-627, 2024
372024
Alkyl sulfinates as cross-coupling partners for programmable and stereospecific installation of C(sp3) bioisosteres
M Zhou, J Tsien, R Dykstra, JME Hughes, BK Peters, RR Merchant, ...
Nature chemistry 15 (4), 550-559, 2023
182023
Programmable late-stage functionalization of bridge-substituted bicyclo [1.1. 1] pentane bis-boronates
Y Yang, J Tsien, R Dykstra, SJ Chen, JB Wang, RR Merchant, ...
Nature chemistry 16 (2), 285-293, 2024
162024
Characterization of the endogenous DAF-12 ligand and its use as an anthelmintic agent in Strongyloides stercoralis
Z Wang, MC Cheong, J Tsien, H Deng, T Qin, JDC Stoltzfus, TG Jaleta, ...
Elife 10, e73535, 2021
142021
A general three-component alkyl petasis boron–mannich reaction
C Hu, J Tsien, SJ Chen, M Kong, RR Merchant, Y Kanda, T Qin
Journal of the American Chemical Society 146 (31), 21769-21777, 2024
82024
Synthesis of multi-substituted bicycloalkyl boronates: An intramolecular coupling approach to alkyl bioisosteres
Y Yang, J Tsien, J Hughes, B Peters, R Merchant, T Qin
52021
Unsymmetrical heterocycle cross-couplings enabled by sulfur (IV) reagents
M Zhou, J Tsien, T Qin
Synlett 31 (20), 1962-1966, 2020
52020
Direct binding to sterols accelerates endoplasmic reticulum-associated degradation of HMG CoA reductase
RA Faulkner, Y Yang, J Tsien, T Qin, RA DeBose-Boyd
Proceedings of the National Academy of Sciences 121 (7), e2318822121, 2024
22024
Corrigendum to: Sulfur (IV)-Mediated Unsymmetrical Heterocycle Cross-Couplings (Angewandte Chemie International Edition,(2020), 59, 19,(7372-7376), 10.1002/anie. 201915425)
M Zhou, J Tsien, T Qin
Angewandte Chemie-International Edition 60 (11), 5601, 2021
12021
Structure-Based Discovery and Development of Highly Potent Dihydroorotate Dehydrogenase Inhibitors for Malaria Chemoprevention
Z Nie, R Bonnert, J Tsien, X Deng, C Higgs, F El Mazouni, X Zhang, R Li, ...
Journal of Medicinal Chemistry 68 (1), 590-637, 2024
2024
Isosteric 3D Bicyclo [1.1. 1] Pentane (BCP) Core-Based Lipids for mRNA Delivery and CRISPR/Cas Gene Editing
S Wu, Y Yang, X Lian, F Zhang, C Hu, J Tsien, Z Chen, Y Sun, A Vaidya, ...
Journal of the American Chemical Society 146 (50), 34733-34742, 2024
2024
A General Redox-Neutral Platform for Radical Cross-Coupling
Á Péter, J Sun, J He, J Tsien, H Zhang, B Vokits, D Peters, M Mandler, ...
2024
Sulfur (IV)-Mediated Unsymmetrical Heterocycle Cross-Couplings (vol 17, pg 7372, 2020)
M Zhou, J Tsien, T Qin
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 60 (11), 5601-5601, 2021
2021
Berichtigung: Sulfur (IV)‐Mediated Unsymmetrical Heterocycle Cross‐Couplings.
M Zhou, J Tsien, T Qin
Angewandte Chemie 133 (11), 2021
2021
S (IV)–Mediated Unsymmetrical Heterocycle Cross-Couplings
M Zhou, J Tsien, T Qin
2019
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