Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine S Ito, L Shen, Q Dai, SC Wu, LB Collins, JA Swenberg, C He, Y Zhang Science 333 (6047), 1300-1303, 2011 | 3996 | 2011 |
N6-methyladenosine-dependent regulation of messenger RNA stability X Wang, Z Lu, A Gomez, GC Hon, Y Yue, D Han, Y Fu, M Parisien, Q Dai, ... Nature 505 (7481), 117-120, 2014 | 3937 | 2014 |
N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO G Jia, YE Fu, XU Zhao, Q Dai, G Zheng, Y Yang, C Yi, T Lindahl, T Pan, ... Nature chemical biology 7 (12), 885-887, 2011 | 3851 | 2011 |
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility G Zheng, JA Dahl, Y Niu, P Fedorcsak, CM Huang, CJ Li, CB Vågbø, ... Molecular cell 49 (1), 18-29, 2013 | 3294 | 2013 |
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA YF He, BZ Li, Z Li, P Liu, Y Wang, Q Tang, J Ding, Y Jia, Z Chen, L Li, ... Science 333 (6047), 1303-1307, 2011 | 3223 | 2011 |
N6-methyladenosine modulates messenger RNA translation efficiency X Wang, BS Zhao, IA Roundtree, Z Lu, D Han, H Ma, X Weng, K Chen, ... Cell 161 (6), 1388-1399, 2015 | 3166 | 2015 |
A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation J Liu, Y Yue, D Han, X Wang, Y Fu, L Zhang, G Jia, M Yu, Z Lu, X Deng, ... Nature chemical biology 10 (2), 93-95, 2014 | 3005 | 2014 |
Dynamic RNA modifications in gene expression regulation IA Roundtree, ME Evans, T Pan, C He Cell 169 (7), 1187-1200, 2017 | 2976 | 2017 |
Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation H Huang, H Weng, W Sun, X Qin, H Shi, H Wu, BS Zhao, A Mesquita, ... Nature cell biology 20 (3), 285-295, 2018 | 2368 | 2018 |
Post-transcriptional gene regulation by mRNA modifications BS Zhao, IA Roundtree, C He Nature reviews Molecular cell biology 18 (1), 31-42, 2017 | 2071 | 2017 |
Gold-catalyzed organic transformations Z Li, C Brouwer, C He Chemical reviews 108 (8), 3239-3265, 2008 | 2049 | 2008 |
Global epigenomic reconfiguration during mammalian brain development R Lister, EA Mukamel, JR Nery, M Urich, CA Puddifoot, ND Johnson, ... Science 341 (6146), 1237905, 2013 | 2010 | 2013 |
N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions N Liu, Q Dai, G Zheng, C He, M Parisien, T Pan Nature 518 (7540), 560-564, 2015 | 1915 | 2015 |
Gene expression regulation mediated through reversible m6A RNA methylation Y Fu, D Dominissini, G Rechavi, C He Nature Reviews Genetics 15 (5), 293-306, 2014 | 1819 | 2014 |
YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA H Shi, X Wang, Z Lu, BS Zhao, H Ma, PJ Hsu, C Liu, C He Cell research 27 (3), 315-328, 2017 | 1647 | 2017 |
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation K Moran-Crusio, L Reavie, A Shih, O Abdel-Wahab, D Ndiaye-Lobry, ... Cancer cell 20 (1), 11-24, 2011 | 1520 | 2011 |
Where, when, and how: context-dependent functions of RNA methylation writers, readers, and erasers H Shi, J Wei, C He Molecular cell 74 (4), 640-650, 2019 | 1497 | 2019 |
FTO plays an oncogenic role in acute myeloid leukemia as a N6-methyladenosine RNA demethylase Z Li, H Weng, R Su, X Weng, Z Zuo, C Li, H Huang, S Nachtergaele, ... Cancer cell 31 (1), 127-141, 2017 | 1384 | 2017 |
m6A demethylase ALKBH5 maintains tumorigenicity of glioblastoma stem-like cells by sustaining FOXM1 expression and cell proliferation program S Zhang, BS Zhao, A Zhou, K Lin, S Zheng, Z Lu, Y Chen, EP Sulman, ... Cancer cell 31 (4), 591-606. e6, 2017 | 1346 | 2017 |
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine CX Song, KE Szulwach, Y Fu, Q Dai, C Yi, X Li, Y Li, CH Chen, W Zhang, ... Nature biotechnology 29 (1), 68-72, 2011 | 1216 | 2011 |