| CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer LM McLane, MS Abdel-Hakeem, EJ Wherry Annual Review of Immunology 37, 2019 | 1709 | 2019 |
| Developmental relationships of four exhausted CD8+ T cell subsets reveals underlying transcriptional and epigenetic landscape control mechanisms JC Beltra, S Manne, MS Abdel-Hakeem, M Kurachi, JR Giles, Z Chen, ... Immunity 52 (5), 825-841. e8, 2020 | 779 | 2020 |
| Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation. MS Abdel-Hakeem, S Manne, JC Beltra, E Stelekati, Z Chen, K Nzingha, ... Nature Immunology 22, 1008-1019, 2021 | 189 | 2021 |
| Early Interferon Therapy for Hepatitis C Virus Infection Rescues Polyfunctional, Long-Lived CD8+ Memory T Cells G Badr, N Bédard, MS Abdel-Hakeem, L Trautmann, B Willems, ... Journal of virology 82 (20), 10017-10031, 2008 | 168 | 2008 |
| In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer SJ Chen Z, Arai E, Khan O, Zhang Z, Ngiow SF, He Y, Huang H, Manne S, Cao Z ... Cell 184 (5), 1262-1280, 2021 | 156 | 2021 |
| Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics JR Giles, SF Ngiow, S Manne, AE Baxter, O Khan, P Wang, R Staupe, ... Nature immunology 23 (11), 1600-1613, 2022 | 145 | 2022 |
| Protective immunity against hepatitis C: many shades of gray MS Abdel-Hakeem, NH Shoukry Frontiers in immunology 5, 274, 2014 | 137 | 2014 |
| Inhibitory signaling sustains a distinct early memory CD8+ T cell precursor that is resistant to DNA damage JB Johnnidis, Y Muroyama, SF Ngiow, Z Chen, S Manne, Z Cai, S Song, ... Science Immunology 6 (55), 2021 | 78 | 2021 |
| Signatures of protective memory immune responses during hepatitis C virus reinfection MS Abdel-Hakeem, N Bédard, D Murphy, J Bruneau, NH Shoukry Gastroenterology 147 (4), 870-881. e8, 2014 | 70 | 2014 |
| Comparison of immune restoration in early versus late alpha interferon therapy against hepatitis C virus MS Abdel-Hakeem, N Bédard, G Badr, M Ostrowski, RP Sékaly, ... Journal of virology 84 (19), 10429-10435, 2010 | 70 | 2010 |
| HCV RNA Activates APCs via TLR7/TLR8 While Virus Selectively Stimulates Macrophages Without Inducing Antiviral Responses. YW Zhang, M El-Far, FP Dupuy, MS Abdel-Hakeem, Z He, FA Procopio, ... Scientific Reports 6, 2016 | 63 | 2016 |
| The long noncoding RNA Morrbid regulates CD8 T cells in response to viral infection JJ Kotzin, F Iseka, J Wright, MB Basavappa, ML Clark, MA Ali, ... PNAS, 2019 | 59 | 2019 |
| Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure JC Beltra, MS Abdel-Hakeem, S Manne, Z Zhang, H Huang, M Kurachi, ... Immunity 56 (12), 2699-2718. e11, 2023 | 52* | 2023 |
| Signaling through FcγRIIA and the C5a-C5aR pathway mediate platelet hyperactivation in COVID-19 SA Apostolidis, A Sarkar, HM Giannini, RR Goel, D Mathew, A Suzuki, ... Frontiers in immunology 13, 834988, 2022 | 49 | 2022 |
| Viruses Teaching Immunology: Role of LCMV Model and Human Viral Infections in Immunological Discoveries MS Abdel-Hakeem Viruses 11 (2), 2019 | 43 | 2019 |
| Selective expansion of high functional avidity memory CD8 T cell clonotypes during hepatitis C virus reinfection and clearance MS Abdel Hakeem, M Boisvert, J Bruneau, H Soudeyns, NH Shoukry PLOS Pathogen 13 (2), e1006191, 2017 | 43 | 2017 |
| Glycogen synthase kinase 3β inhibitors prevent hepatitis C virus release/assembly through perturbation of lipid metabolism MA Sarhan, MS Abdel-Hakeem, AL Mason, DL Tyrrell, M Houghton Scientific Reports 7 (1), 2495, 2017 | 35 | 2017 |
| The hedgehog pathway suppresses neuropathogenesis in CD4 T cell-driven inflammation N Benallegue, H Kebir, R Kapoor, A Crockett, C Li, L Cheslow, ... Brain 144 (6), 1670-1683, 2021 | 24 | 2021 |
| MicroRNA-29a attenuates CD8 T cell exhaustion and induces memory-like CD8 T cells during chronic infection E Stelekati, Z Cai, S Manne, Z Chen, JC Beltra, LA Buchness, X Leng, ... Proceedings of the National Academy of Sciences 119 (17), e2106083119, 2022 | 12 | 2022 |
| The 7th Canadian Symposium on hepatitis C virus:“Toward elimination of HCV: how to get there” ML Cheng, MS Abdel-Hakeem, SE Cousineau, J Grebely, AD Marshall, ... Canadian Liver Journal, 139-152, 2018 | 11 | 2018 |
Naglaa H. ShoukryProfessor of Medicine, Université de Montréal and Centre de Recherche du CHUM (CRCHUM)Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα umontreal.ca
