| Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes JC Milne, PD Lambert, S Schenk, DP Carney, JJ Smith, DJ Gagne, L Jin, ... Nature 450 (7170), 712-716, 2007 | 2060 | 2007 |
| Insulin sensitivity: modulation by nutrients and inflammation S Schenk, M Saberi, JM Olefsky The Journal of clinical investigation 118 (9), 2992-3002, 2008 | 1627 | 2008 |
| A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange Y Liu, R Dentin, D Chen, S Hedrick, K Ravnskjaer, S Schenk, J Milne, ... Nature 456 (7219), 269-273, 2008 | 649 | 2008 |
| Increased adipocyte O2 consumption triggers HIF-1α, causing inflammation and insulin resistance in obesity YS Lee, J Kim, O Osborne, R Sasik, S Schenk, A Chen, H Chung, ... Cell 157 (6), 1339-1352, 2014 | 620 | 2014 |
| Hematopoietic cell-specific deletion of toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice M Saberi, NB Woods, C de Luca, S Schenk, JC Lu, G Bandyopadhyay, ... Cell metabolism 10 (5), 419-429, 2009 | 570 | 2009 |
| Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid–induced insulin resistance S Schenk, JF Horowitz The Journal of clinical investigation 117 (6), 1690-1698, 2007 | 512 | 2007 |
| SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes T Yoshizaki, JC Milne, T Imamura, S Schenk, N Sonoda, JL Babendure, ... Molecular and cellular biology 29 (5), 1363-1374, 2009 | 499 | 2009 |
| SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity T Yoshizaki, S Schenk, T Imamura, JL Babendure, N Sonoda, EJ Bae, ... American journal of physiology-endocrinology and metabolism 298 (3), E419-E428, 2010 | 484 | 2010 |
| Ceramides contained in LDL are elevated in type 2 diabetes and promote inflammation and skeletal muscle insulin resistance J Boon, AJ Hoy, R Stark, RD Brown, RC Meex, DC Henstridge, S Schenk, ... Diabetes 62 (2), 401-410, 2013 | 332 | 2013 |
| NAD+/NADH and skeletal muscle mitochondrial adaptations to exercise AT White, S Schenk American Journal of Physiology-Endocrinology and Metabolism 303 (3), E308-E321, 2012 | 271 | 2012 |
| Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females V Ribas, BG Drew, Z Zhou, J Phun, NY Kalajian, T Soleymani, P Daraei, ... Science translational medicine 8 (334), 334ra54-334ra54, 2016 | 238 | 2016 |
| Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) deacetylation … A Philp, A Chen, D Lan, GA Meyer, AN Murphy, AE Knapp, IM Olfert, ... Journal of Biological Chemistry 286 (35), 30561-30570, 2011 | 230 | 2011 |
| Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction S Schenk, CE McCurdy, A Philp, MZ Chen, MJ Holliday, ... The Journal of clinical investigation 121 (11), 4281-4288, 2011 | 222 | 2011 |
| Molecular transducers of physical activity consortium (MoTrPAC): mapping the dynamic responses to exercise JA Sanford, CD Nogiec, ME Lindholm, JN Adkins, D Amar, S Dasari, ... Cell 181 (7), 1464-1474, 2020 | 219 | 2020 |
| Different glycemic indexes of breakfast cereals are not due to glucose entry into blood but to glucose removal by tissue S Schenk, CJ Davidson, TW Zderic, LO Byerley, EF Coyle The American journal of clinical nutrition 78 (4), 742-748, 2003 | 168 | 2003 |
| Coimmunoprecipitation of FAT/CD36 and CPT I in skeletal muscle increases proportionally with fat oxidation after endurance exercise training S Schenk, JF Horowitz American Journal of Physiology-Endocrinology and Metabolism 291 (2), E254-E260, 2006 | 155 | 2006 |
| Improved insulin sensitivity after weight loss and exercise training is mediated by a reduction in plasma fatty acid mobilization, not enhanced oxidative capacity S Schenk, MP Harber, CR Shrivastava, CF Burant, JF Horowitz The Journal of physiology 587 (20), 4949-4961, 2009 | 154 | 2009 |
| High-fat diet elevates resting intramuscular triglyceride concentration and whole body lipolysis during exercise TW Zderic, CJ Davidson, S Schenk, LO Byerley, EF Coyle American Journal of Physiology-Endocrinology and Metabolism 286 (2), E217-E225, 2004 | 147 | 2004 |
| Discovery of Imidazo[1,2-b]thiazole Derivatives as Novel SIRT1 Activators CB Vu, JE Bemis, JS Disch, PY Ng, JJ Nunes, JC Milne, DP Carney, ... Journal of medicinal chemistry 52 (5), 1275-1283, 2009 | 146 | 2009 |
| Regulation of plasma ceramide levels with fatty acid oversupply: evidence that the liver detects and secretes de novo synthesised ceramide MJ Watt, AC Barnett, CR Bruce, S Schenk, JF Horowitz, AJ Hoy Diabetologia 55, 2741-2746, 2012 | 132 | 2012 |
Jerrold OlefskyUniversity of California San DiegoΗ διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα ucsd.edu
