Παρακολούθηση
Julian Rayner
Julian Rayner
Director, Cambridge Institute for Medical Research, University of Cambridge
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα cam.ac.uk - Αρχική σελίδα
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Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis
M Zhang, C Wang, TD Otto, J Oberstaller, X Liao, SR Adapa, K Udenze, ...
Science 360 (6388), eaap7847, 2018
9072018
Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum
C Crosnier, LY Bustamante, SJ Bartholdson, AK Bei, M Theron, ...
Nature 480 (7378), 534-537, 2011
8212011
Origin of the human malaria parasite Plasmodium falciparum in gorillas
W Liu, Y Li, GH Learn, RS Rudicell, JD Robertson, BF Keele, ...
Nature 467 (7314), 420-425, 2010
7212010
Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia
O Miotto, J Almagro-Garcia, M Manske, B MacInnis, S Campino, ...
Nature genetics 45 (6), 648-655, 2013
5732013
Functional profiling of a Plasmodium genome reveals an abundance of essential genes
E Bushell, AR Gomes, T Sanderson, B Anar, G Girling, C Herd, T Metcalf, ...
Cell 170 (2), 260-272. e8, 2017
5692017
Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing
M Manske, O Miotto, S Campino, S Auburn, J Almagro-Garcia, G Maslen, ...
Nature 487 (7407), 375-379, 2012
5662012
A novel multiple-stage antimalarial agent that inhibits protein synthesis
B Baragaña, I Hallyburton, MCS Lee, NR Norcross, R Grimaldi, TD Otto, ...
Nature 522 (7556), 315-320, 2015
4862015
Malaria vaccines: recent advances and new horizons
SJ Draper, BK Sack, CR King, CM Nielsen, JC Rayner, MK Higgins, ...
Cell host & microbe 24 (1), 43-56, 2018
4172018
Revealing the Sequence and Resulting Cellular Morphology of Receptor-Ligand Interactions during Plasmodium falciparum Invasion of Erythrocytes
GE Weiss, PR Gilson, T Taechalertpaisarn, WH Tham, NWM de Jong, ...
PLoS pathogens 11 (2), e1004670, 2015
3882015
Phenotypic variation of Plasmodium falciparum merozoite proteins directs receptor targeting for invasion of human erythrocytes
MT Duraisingh, T Triglia, SA Ralph, JC Rayner, JW Barnwell, ...
The EMBO journal, 2003
3462003
African origin of the malaria parasite Plasmodium vivax
W Liu, Y Li, KS Shaw, GH Learn, LJ Plenderleith, JA Malenke, ...
Nature communications 5 (1), 3346, 2014
2822014
The Malaria Cell Atlas: Single parasite transcriptomes across the complete Plasmodium life cycle
VM Howick, AJC Russell, T Andrews, H Heaton, AJ Reid, K Natarajan, ...
Science 365 (6455), eaaw2619, 2019
2692019
Plasmodium falciparum Erythrocyte Invasion: Combining Function with Immune Evasion
GJ Wright, JC Rayner
PLoS pathogens 10 (3), e1003943, 2014
2512014
A Plasmodium falciparum Homologue of Plasmodium vivax Reticulocyte Binding Protein (PvRBP1) Defines a Trypsin-resistant Erythrocyte Invasion Pathway
JC Rayner, E Vargas-Serrato, CS Huber, MR Galinski, JW Barnwell
The Journal of experimental medicine 194 (11), 1571-1582, 2001
2462001
Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum
A Miles, Z Iqbal, P Vauterin, R Pearson, S Campino, M Theron, K Gould, ...
Genome research 26 (9), 1288-1299, 2016
2412016
Generation of Antigenic Diversity in Plasmodium falciparum by Structured Rearrangement of Var Genes During Mitosis
A Claessens, WL Hamilton, M Kekre, TD Otto, A Faizullabhoy, JC Rayner, ...
PLoS genetics 10 (12), e1004812, 2014
2332014
Evolution of human-chimpanzee differences in malaria susceptibility: relationship to human genetic loss of N-glycolylneuraminic acid
MJ Martin, JC Rayner, P Gagneux, JW Barnwell, A Varki
Proceedings of the National Academy of Sciences 102 (36), 12819-12824, 2005
2232005
Phosphoinositide Metabolism Links cGMP-Dependent Protein Kinase G to Essential Ca2+ Signals at Key Decision Points in the Life Cycle of Malaria Parasites
M Brochet, MO Collins, TK Smith, E Thompson, S Sebastian, K Volkmann, ...
PLoS biology 12 (3), e1001806, 2014
2222014
A knockout screen of ApiAP2 genes reveals networks of interacting transcriptional regulators controlling the Plasmodium life cycle
K Modrzynska, C Pfander, L Chappell, L Yu, C Suarez, K Dundas, ...
Cell host & microbe 21 (1), 11-22, 2017
2182017
New antigens for a multicomponent blood-stage malaria vaccine
FH Osier, MJ Mackinnon, C Crosnier, G Fegan, G Kamuyu, M Wanaguru, ...
Science translational medicine 6 (247), 247ra102-247ra102, 2014
2122014
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