Παρακολούθηση
Michael V. LeVine
Michael V. LeVine
Director of Computational Biophysics, Genesis Therapeutics
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα genesistherapeutics.ai - Αρχική σελίδα
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Παρατίθεται από
Παρατίθεται από
Έτος
Spontaneous Inward Opening of the Dopamine Transporter Is Triggered by PIP2-Regulated Dynamics of the N-Terminus
G Khelashvili, N Stanley, MA Sahai, J Medina, MV LeVine, L Shi, ...
ACS chemical neuroscience 6 (11), 1825-1837, 2015
1122015
NbIT-a new information theory-based analysis of allosteric mechanisms reveals residues that underlie function in the leucine transporter LeuT
MV LeVine, H Weinstein
PLoS computational biology 10 (5), e1003603, 2014
1022014
A functional selectivity mechanism at the serotonin-2A GPCR involves ligand-dependent conformations of intracellular loop 2
JM Perez-Aguilar, J Shan, MV LeVine, G Khelashvili, H Weinstein
Journal of the American Chemical Society 136 (45), 16044-16054, 2014
932014
Ligand modulation of sidechain dynamics in a wild-type human GPCR
LD Clark, I Dikiy, K Chapman, KEJ Rödström, J Aramini, MV LeVine, ...
Elife 6, e28505, 2017
892017
A new computational method for membrane compressibility: Bilayer mechanical thickness revisited
M Doktorova, MV LeVine, G Khelashvili, H Weinstein
Biophysical journal 116 (3), 487-502, 2019
812019
Allosteric mechanisms of molecular machines at the membrane: transport by sodium-coupled symporters
MV LeVine, MA Cuendet, G Khelashvili, H Weinstein
Chemical reviews 116 (11), 6552-6587, 2016
802016
Computational approaches to detect allosteric pathways in transmembrane molecular machines
S Stolzenberg, M Michino, MV LeVine, H Weinstein, L Shi
Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (7), 1652-1662, 2016
642016
Development of force field parameters for the simulation of single-and double-stranded DNA molecules and DNA–protein complexes
MR Tucker, S Piana, D Tan, MV LeVine, DE Shaw
The Journal of Physical Chemistry B 126 (24), 4442-4457, 2022
532022
A partially-open inward-facing intermediate conformation of LeuT is associated with Na+ release and substrate transport
DS Terry, RA Kolster, M Quick, MV LeVine, G Khelashvili, Z Zhou, ...
Nature communications 9 (1), 230, 2018
462018
X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release
K Gotfryd, T Boesen, JS Mortensen, G Khelashvili, M Quick, DS Terry, ...
Nature Communications 11 (1), 1005, 2020
452020
Molecular dynamics simulations related to Sars-Cov-2
DE Shaw
DE Shaw Research Technical Data, 2020
452020
The membrane protein LeuT in micellar systems: aggregation dynamics and detergent binding to the S2 site
G Khelashvili, MV LeVine, L Shi, M Quick, JA Javitch, H Weinstein
Journal of the American Chemical Society 135 (38), 14266-14275, 2013
352013
The allostery landscape: Quantifying thermodynamic couplings in biomolecular systems
MA Cuendet, H Weinstein, MV LeVine
Biophysical Journal 112 (3), 354a, 2017
332017
The allosteric mechanism of substrate-specific transport in SLC6 is mediated by a volumetric sensor
MV LeVine, DS Terry, G Khelashvili, ZS Siegel, M Quick, JA Javitch, ...
Proceedings of the National Academy of Sciences 116 (32), 15947-15956, 2019
222019
AIM for allostery: using the Ising model to understand information processing and transmission in allosteric biomolecular systems
MV LeVine, H Weinstein
Entropy 17 (5), 2895-2918, 2015
222015
Thermodynamic coupling function analysis of allosteric mechanisms in the human dopamine transporter
MV LeVine, MA Cuendet, AM Razavi, G Khelashvili, H Weinstein
Biophysical Journal 114 (1), 10-14, 2018
162018
The allosteric mechanism leading to an open-groove lipid conductive state of the TMEM16F scramblase
G Khelashvili, E Kots, X Cheng, MV Levine, H Weinstein
Communications Biology 5 (1), 990, 2022
142022
Role of annular lipids in the functional properties of leucine transporter LeuT proteomicelles
MV LeVine, G Khelashvili, L Shi, M Quick, JA Javitch, H Weinstein
Biochemistry 55 (6), 850-859, 2016
142016
N-body information theory (NbIT) analysis of rigid-body dynamics in intracellular loop 2 of the 5-HT2A receptor
MV LeVine, JM Perez-Aguilar, H Weinstein
arXiv preprint arXiv:1406.4730, 2014
92014
Effects of dextromethorphan on zebrafish larval development
F Scalzo, M Levine
Neurotoxicology and Teratology 4 (31), 250, 2009
22009
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