An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules A Basu, NE Bodycombe, JH Cheah, EV Price, K Liu, GI Schaefer, ... Cell 154 (5), 1151-1161, 2013 | 823 | 2013 |
Correlating chemical sensitivity and basal gene expression reveals mechanism of action MG Rees, B Seashore-Ludlow, JH Cheah, DJ Adams, EV Price, S Gill, ... Nature chemical biology 12 (2), 109-116, 2016 | 804 | 2016 |
Harnessing connectivity in a large-scale small-molecule sensitivity dataset B Seashore-Ludlow, MG Rees, JH Cheah, M Cokol, EV Price, ME Coletti, ... Cancer discovery 5 (11), 1210-1223, 2015 | 727 | 2015 |
Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles PA Clemons, NE Bodycombe, HA Carrinski, JA Wilson, AF Shamji, ... Proceedings of the National Academy of Sciences 107 (44), 18787-18792, 2010 | 358 | 2010 |
ChemBank : a small-molecule screening and cheminformatics resource database KP Seiler, GA George, MP Happ, NE Bodycombe, HA Carrinski, S Norton, ... Nucleic acids research 36 (suppl_1), D351-D359, 2007 | 356 | 2007 |
Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling MJ Wawer, K Li, SM Gustafsdottir, V Ljosa, NE Bodycombe, MA Marton, ... Proceedings of the National Academy of Sciences 111 (30), 10911-10916, 2014 | 201 | 2014 |
A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay MA Bray, SM Gustafsdottir, MH Rohban, S Singh, V Ljosa, KL Sokolnicki, ... Gigascience 6 (12), giw014, 2017 | 169 | 2017 |
Mammalian transforming growth factor β1 activated after ingestion by Anopheles stephensi modulates mosquito immunity S Luckhart, AL Crampton, R Zamora, MJ Lieber, PC Dos Santos, ... Infection and immunity 71 (6), 3000-3009, 2003 | 85 | 2003 |
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Small-molecule suppressors of cytokine-induced β-cell apoptosis DHC Chou, NE Bodycombe, HA Carrinski, TA Lewis, PA Clemons, ... ACS chemical biology 5 (8), 729-734, 2010 | 51 | 2010 |
Connecting small molecules with similar assay performance profiles leads to new biological hypotheses V Dančík, H Carrel, NE Bodycombe, KP Seiler, D Fomina-Yadlin, ... Journal of biomolecular screening 19 (5), 771-781, 2014 | 41 | 2014 |
A flow cytometry-based screen identifies MBNL1 modulators that rescue splicing defects in myotonic dystrophy type I F Zhang, NE Bodycombe, KM Haskell, YL Sun, ET Wang, CA Morris, ... Human molecular genetics 26 (16), 3056-3068, 2017 | 37 | 2017 |
A small-molecule screening strategy to identify suppressors of statin myopathy BK Wagner, TJ Gilbert, J Hanai, S Imamura, NE Bodycombe, RS Bon, ... ACS chemical biology 6 (9), 900-904, 2011 | 24 | 2011 |
An economic framework to prioritize confirmatory tests after a high-throughput screen SJ Swamidass, JA Bittker, NE Bodycombe, SP Ryder, PA Clemons Journal of biomolecular screening 15 (6), 680-686, 2010 | 21 | 2010 |
Enhancing the rate of scaffold discovery with diversity-oriented prioritization SJ Swamidass, BT Calhoun, JA Bittker, NE Bodycombe, PA Clemons Bioinformatics 27 (16), 2271-2278, 2011 | 13 | 2011 |
Master data management: getting your house in order K Petri Seiler, N E. Bodycombe, T Hawkins, R Shell, A Lemon, ... Combinatorial Chemistry & High Throughput Screening 14 (9), 749-756, 2011 | 8 | 2011 |
Utility-aware screening with clique-oriented prioritization SJ Swamidass, BT Calhoun, JA Bittker, NE Bodycombe, PA Clemons Journal of chemical information and modeling 52 (1), 29-37, 2012 | 7 | 2012 |
The many facets of screening library design M Boehm, L Zhang, N Bodycombe, M Maciejewski, AM Wassermann Frontiers in Molecular Design and Chemical Information Science-Herman …, 2016 | 1 | 2016 |
Small-molecule screening for suppressors of beta-cell apoptosis induced by inflammatory cytokines DHC Chou, PW Faloon, HA Carrinski, NE Bodycombe, PA Clemons, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 240, 2010 | | 2010 |