Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity E Volz, V Hill, JT McCrone, A Price, D Jorgensen, Á O’Toole, J Southgate, ... Cell 184 (1), 64-75. e11, 2021 | 1172 | 2021 |
Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B. 1.617. 2) compared with alpha (B. 1.1. 7) variants of concern: a cohort study KA Twohig, T Nyberg, A Zaidi, S Thelwall, MA Sinnathamby, S Aliabadi, ... The Lancet Infectious Diseases 22 (1), 35-42, 2022 | 889 | 2022 |
Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms SE Jones, JM Lane, AR Wood, VT van Hees, J Tyrrell, RN Beaumont, ... Nature communications 10 (1), 343, 2019 | 615 | 2019 |
Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B. 1.1. 7 B Meng, SA Kemp, G Papa, R Datir, IATM Ferreira, S Marelli, WT Harvey, ... Cell reports 35 (13), 2021 | 466 | 2021 |
Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits CCY Wong, EL Meaburn, A Ronald, TS Price, AR Jeffries, LC Schalkwyk, ... Molecular psychiatry 19 (4), 495-503, 2014 | 396 | 2014 |
Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B. 1.1. 7: an ecological study MS Graham, CH Sudre, A May, M Antonelli, B Murray, T Varsavsky, ... The Lancet Public Health 6 (5), e335-e345, 2021 | 374 | 2021 |
Allelic skewing of DNA methylation is widespread across the genome LC Schalkwyk, EL Meaburn, R Smith, EL Dempster, AR Jeffries, ... The American Journal of Human Genetics 86 (2), 196-212, 2010 | 293 | 2010 |
An integrated national scale SARS-CoV-2 genomic surveillance network T COVID The Lancet. Microbe 1 (3), e99, 2020 | 188 | 2020 |
Molecular and phenotypic characterization of ring chromosome 22 AR Jeffries, S Curran, F Elmslie, A Sharma, S Wenger, M Hummel, ... American journal of medical genetics Part A 137 (2), 139-147, 2005 | 138 | 2005 |
Exponential growth, high prevalence of SARS-CoV-2, and vaccine effectiveness associated with the Delta variant P Elliott, D Haw, H Wang, O Eales, CE Walters, KEC Ainslie, C Atchison, ... Science 374 (6574), eabl9551, 2021 | 135 | 2021 |
Knockdown of the psychosis susceptibility gene ZNF804A alters expression of genes involved in cell adhesion MJ Hill, AR Jeffries, RJB Dobson, J Price, NJ Bray Human molecular genetics 21 (5), 1018-1024, 2012 | 117 | 2012 |
Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing SK Leung, AR Jeffries, I Castanho, BT Jordan, K Moore, JP Davies, ... Cell reports 37 (7), 2021 | 115 | 2021 |
Purmorphamine increases DARPP-32 differentiation in human striatal neural stem cells through the Hedgehog pathway G El-Akabawy, LM Medina, A Jeffries, J Price, M Modo Stem cells and development 20 (11), 1873-1887, 2011 | 79 | 2011 |
RE1 Silencing transcription factor maintains a repressive chromatin environment in embryonic hippocampal neural stem cells DJ Greenway, M Street, A Jeffries, NJ Buckley Stem cells 25 (2), 354-363, 2007 | 79 | 2007 |
The impact of viral mutations on recognition by SARS-CoV-2 specific T cells TI de Silva, G Liu, BB Lindsey, D Dong, SC Moore, NS Hsu, D Shah, ... Iscience 24 (11), 2021 | 75 | 2021 |
Stochastic choice of allelic expression in human neural stem cells AR Jeffries, LW Perfect, J Ledderose, LC Schalkwyk, NJ Bray, J Mill, ... Stem cells 30 (9), 1938-1947, 2012 | 67 | 2012 |
Persister Escherichia coli cells have a lower intracellular pH than susceptible cells but maintain their pH in response to antibiotic treatment O Goode, A Smith, A Zarkan, J Cama, BM Invergo, D Belgami, ... MBio 12 (4), 10.1128/mbio. 00909-21, 2021 | 61 | 2021 |
Transcriptional signatures of tau and amyloid neuropathology I Castanho, TK Murray, E Hannon, A Jeffries, E Walker, E Laing, H Baulf, ... Cell Reports 30 (6), 2040-2054. e5, 2020 | 60 | 2020 |
The utility of patient specific induced pluripotent stem cells for the modelling of Autistic Spectrum Disorders G Cocks, S Curran, P Gami, D Uwanogho, AR Jeffries, A Kathuria, ... Psychopharmacology 231, 1079-1088, 2014 | 57 | 2014 |
Growth disrupting mutations in epigenetic regulatory molecules are associated with abnormalities of epigenetic aging AR Jeffries, R Maroofian, CG Salter, BA Chioza, HE Cross, MA Patton, ... Genome research 29 (7), 1057-1066, 2019 | 51 | 2019 |