Παρακολούθηση
Sandesh Chopade
Sandesh Chopade
Research Fellow, University College London
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα ucl.ac.uk
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Παρατίθεται από
Παρατίθεται από
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Genetic drug target validation using Mendelian randomisation
AF Schmidt, C Finan, M Gordillo-Marañón, FW Asselbergs, DF Freitag, ...
Nature communications 11 (1), 3255, 2020
3612020
Improving the odds of drug development success through human genomics: modelling study
AD Hingorani, V Kuan, C Finan, FA Kruger, A Gaulton, S Chopade, ...
Scientific reports 9 (1), 18911, 2019
2272019
Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study
V Kuan, S Denaxas, P Patalay, D Nitsch, R Mathur, A Gonzalez-Izquierdo, ...
The Lancet Digital Health 5 (1), e16-e27, 2023
932023
Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney
JM Eales, X Jiang, X Xu, S Saluja, A Akbarov, E Cano-Gamez, ...
Nature Genetics 53 (5), 630-637, 2021
582021
Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification
M Kavousi, MM Bos, HJ Barnes, CL Lino Cardenas, D Wong, H Lu, ...
Nature genetics 55 (10), 1651-1664, 2023
502023
Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation
D Adlam, TE Berrandou, A Georges, CP Nelson, E Giannoulatou, J Henry, ...
Nature Genetics 55 (6), 964-972, 2023
432023
Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics
M Gordillo-Marañón, M Zwierzyna, P Charoen, F Drenos, S Chopade, ...
Nature communications 12 (1), 6120, 2021
242021
Druggable proteins influencing cardiac structure and function: Implications for heart failure therapies and cancer cardiotoxicity
AF Schmidt, M Bourfiss, A Alasiri, E Puyol-Anton, S Chopade, M van Vugt, ...
Science advances 9 (17), eadd4984, 2023
192023
Comparing the effects of CETP in East Asian and European ancestries: a Mendelian randomization study
D Dunca, S Chopade, M Gordillo-Marañón, AD Hingorani, ...
Nature Communications 15 (1), 5302, 2024
72024
Improving the odds of drug development success through human genomics: modelling study. Sci Rep
A Hingorani, V Kuan, C Finan, F Kruger, A Gaulton, S Chopade, R Sofat, ...
62019
Impact of chromosomal heteromorphisms on recurrent miscarriages
S Chopade, DK Chopade, H Harde
Hum Genet Embryol 2, 101, 2012
62012
Exploring the Role of Plasma Lipids and Statin Interventions on Multiple Sclerosis Risk and Severity: A Mendelian Randomization Study
MM Almramhi, C Finan, CS Storm, AF Schmidt, DA Kia, R Coneys, ...
Neurology 101 (17), e1729-e1740, 2023
52023
Mapping the aetiological foundations of the heart failure spectrum using human genetics
A Henry, X Mo, C Finan, MD Chaffin, D Speed, H Issa, S Denaxas, ...
medRxiv, 2023.10. 01.23296379, 2023
52023
Unexpected Inheritance of a Balanced Homologous translocation t (22q; 22q) from father to a phenotypically normal daughter
DK Chopade, H Harde, P Ugale, S Chopade
Indian Journal of Human Genetics 20 (1), 85, 2014
52014
Integrating metabolomics and proteomics to identify novel drug targets for heart failure and atrial fibrillation
M van Vugt, C Finan, S Chopade, R Providencia, CR Bezzina, ...
Genome Medicine 16 (1), 120, 2024
32024
Reproductive Outcomes in 101 Couples with Balanced Chromosomal Rearrangements
D Chopade, S Gangane, S Chopade, H Harde
Human Genet Embryol 8 (2), 150, 2018
32018
Genetic evidence for serum amyloid P component as a drug target in neurodegenerative disorders
AF Schmidt, C Finan, S Chopade, S Ellmerich, MN Rossor, AD Hingorani, ...
Open Biology 14 (7), 230419, 2024
22024
Genetic evidence for serum amyloid P component as a drug target for treatment of neurodegenerative disorders
AF Schmidt, C Finan, S Chopade, S Ellmerich, MN Rossor, AD Hingorani, ...
medRxiv, 2023
22023
Druggable proteins influencing cardiac structure and function: implications for heart failure therapies and cancer related cardiotoxicity
A Schmidt, M Bourfiss, A Alasiri, S Chopade, E Puyol-Anton, M van Vugt, ...
22022
New drug repurposing opportunities for hypertension uncovered by the convergence of genomics with kidney transcriptomics and epigenomics
S Saluja, X Jiang, C Finan, S Chopade, J Eales, X Xu, NJ Samani, ...
Circulation 140 (Suppl_1), A14286-A14286, 2019
22019
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