Graviola: a novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism MP Torres, S Rachagani, V Purohit, P Pandey, S Joshi, ED Moore, ... Cancer letters 323 (1), 29-40, 2012 | 266 | 2012 |
Adapting to stress—chaperome networks in cancer S Joshi, T Wang, TLS Araujo, S Sharma, JL Brodsky, G Chiosis Nature Reviews Cancer 18 (9), 562-575, 2018 | 124 | 2018 |
Gold/alpha-lactalbumin nanoprobes for the imaging and treatment of breast cancer J Yang, T Wang, L Zhao, VK Rajasekhar, S Joshi, C Andreou, S Pal, ... Nature biomedical engineering 4 (7), 686-703, 2020 | 77 | 2020 |
The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction MC Inda, S Joshi, T Wang, A Bolaender, S Gandu, J Koren III, AY Che, ... Nature Communications 11 (1), 319, 2020 | 67 | 2020 |
Dysregulation in T helper 1/T helper 2 cytokine ratios in patients with multiple myeloma A Sharma, R Khan, S Joshi, L Kumar, M Sharma Leukemia & lymphoma 51 (5), 920-927, 2010 | 65 | 2010 |
Smoking accelerates pancreatic cancer progression by promoting differentiation of MDSCs and inducing HB-EGF expression in macrophages S Kumar, MP Torres, S Kaur, S Rachagani, S Joshi, SL Johansson, ... Oncogene 34 (16), 2052-2060, 2015 | 61 | 2015 |
Hypoxia-induced oxidative stress promotes MUC4 degradation via autophagy to enhance pancreatic cancer cells survival S Joshi, S Kumar, MP Ponnusamy, SK Batra Oncogene, 2016 | 55 | 2016 |
Paradigms for precision medicine in epichaperome cancer therapy N Pillarsetty, K Jhaveri, T Taldone, E Caldas-Lopes, B Punzalan, S Joshi, ... Cancer Cell 36 (5), 559-573. e7, 2019 | 53 | 2019 |
Molecular stressors engender protein connectivity dysfunction through aberrant N-glycosylation of a chaperone P Yan, HJ Patel, S Sharma, A Corben, T Wang, P Panchal, C Yang, ... Cell reports 31 (13), 2020 | 51 | 2020 |
NCOA3-mediated upregulation of mucin expression via transcriptional and post-translational changes during the development of pancreatic cancer S Kumar, S Das, S Rachagani, S Kaur, S Joshi, SL Johansson, ... Oncogene 34 (37), 4879-4889, 2015 | 50 | 2015 |
HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons S Kishinevsky, T Wang, A Rodina, SY Chung, C Xu, J Philip, T Taldone, ... Nature communications 9 (1), 4345, 2018 | 49 | 2018 |
Altered Mucins (MUC) trafficking in benign and malignant conditions S Joshi, S Kumar, A Choudhury, MP Ponnusamy, SK Batra Oncotarget 5 (17), 7272, 2014 | 43 | 2014 |
Novel HER3/MUC4 oncogenic signaling aggravates the tumorigenic phenotypes of pancreatic cancer cells SKB Imayavaramban Lakshmanan, Parthasarathy Seshacharyulu, Dhanya Haridas ... Oncotarget, 2015 | 42 | 2015 |
Tumor suppressor FOXO3 mediates signals from the EGF receptor to regulate proliferation of colonic cells W Qi, CR Weber, K Wasland, H Roy, R Wali, S Joshi, SD Savkovic American Journal of Physiology-Gastrointestinal and Liver Physiology 300 (2 …, 2011 | 39 | 2011 |
Angiopoietin-2: a potential novel diagnostic marker in multiple myeloma S Joshi, R Khan, M Sharma, L Kumar, A Sharma Clinical biochemistry 44 (8-9), 590-595, 2011 | 38 | 2011 |
A chemical biology approach to the chaperome in cancer—HSP90 and beyond T Taldone, T Wang, A Rodina, NVK Pillarsetty, CS Digwal, S Sharma, ... Cold Spring Harbor perspectives in biology 12 (4), a034116, 2020 | 37 | 2020 |
Genetic variants of mucins: unexplored conundrum S Kumar, E Cruz, S Joshi, A Patel, R Jahan, SK Batra, M Jain Carcinogenesis 38 (7), 671-679, 2017 | 35 | 2017 |
Bile acids-mediated overexpression of MUC4 via FAK-dependent c-Jun activation in pancreatic cancer S Joshi, E Cruz, S Rachagani, S Guha, RE Brand, MP Ponnusamy, ... Molecular oncology 10 (7), 1063-1077, 2016 | 34 | 2016 |
Genetically engineered mucin mouse models for inflammation and cancer S Joshi, S Kumar, S Bafna, S Rachagani, KU Wagner, M Jain, SK Batra Cancer and Metastasis Reviews 34, 593-609, 2015 | 31 | 2015 |
Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system A Bolaender, D Zatorska, H He, S Joshi, S Sharma, CS Digwal, HJ Patel, ... Nature Communications 12 (1), 4669, 2021 | 27 | 2021 |