Παρακολούθηση
Husain Yar Khan
Husain Yar Khan
Assistant Professor - Research, Karmanos Cancer Institute, Wayne State University School of Medicine
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα karmanos.org - Αρχική σελίδα
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A prooxidant mechanism for the anticancer and chemopreventive properties of plant polyphenols
H Yar Khan, H Zubair, M Fahad Ullah, A Ahmad, S Mumtaz Hadi
Current Drug Targets 13 (14), 1738-1749, 2012
1722012
Redox cycling of endogenous copper by thymoquinone leads to ROS-mediated DNA breakage and consequent cell death: putative anticancer mechanism of antioxidants
H Zubair, HY Khan, A Sohail, S Azim, MF Ullah, A Ahmad, FH Sarkar, ...
Cell death & disease 4 (6), e660-e660, 2013
1482013
Soy isoflavone genistein induces cell death in breast cancer cells through mobilization of endogenous copper ions and generation of reactive oxygen species
MF Ullah, A Ahmad, H Zubair, HY Khan, Z Wang, FH Sarkar, SM Hadi
Molecular nutrition & food research 55 (4), 553-559, 2011
1452011
Effect of vitamins C and E on antioxidant status of breast‐cancer patients undergoing chemotherapy
N Suhail, N Bilal, HY Khan, S Hasan, S Sharma, F Khan, T Mansoor, ...
Journal of clinical pharmacy and therapeutics 37 (1), 22-26, 2012
1392012
Plant polyphenol induced cell death in human cancer cells involves mobilization of intracellular copper ions and reactive oxygen species generation: a mechanism for cancer …
HY Khan, H Zubair, M Faisal, MF Ullah, M Farhan, FH Sarkar, A Ahmad, ...
Molecular nutrition & food research 58 (3), 437-446, 2014
1192014
Resveratrol mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: a putative mechanism for chemoprevention of cancer
SM Hadi, MF Ullah, AS Azmi, A Ahmad, U Shamim, H Zubair, HY Khan
Pharmaceutical research 27, 979-988, 2010
1092010
Cancer therapy by catechins involves redox cycling of copper ions and generation of reactive oxygen species
M Farhan, HY Khan, M Oves, A Al-Harrasi, N Rehmani, H Arif, SM Hadi, ...
Toxins 8 (2), 37, 2016
982016
The antioxidant ascorbic acid mobilizes nuclear copper leading to a prooxidant breakage of cellular DNA: implications for chemotherapeutic action against cancer
MF Ullah, HY Khan, H Zubair, U Shamim, SM Hadi
Cancer chemotherapy and pharmacology 67, 103-110, 2011
852011
Oral administration of copper to rats leads to increased lymphocyte cellular DNA degradation by dietary polyphenols: implications for a cancer preventive mechanism
HY Khan, H Zubair, MF Ullah, A Ahmad, SM Hadi
Biometals 24, 1169-1178, 2011
612011
KRAS G12D targeted therapies for pancreatic cancer: Has the fortress been conquered?
SF Bannoura, HY Khan, AS Azmi
Frontiers in Oncology 12, 1013902, 2022
552022
The prooxidant action of dietary antioxidants leading to cellular DNA breakage and anticancer effects: implications for chemotherapeutic action against cancer
MF Ullah, A Ahmad, HY Khan, H Zubair, FH Sarkar, SM Hadi
Cell biochemistry and biophysics 67, 431-438, 2013
532013
Preclinical assessment with clinical validation of selinexor with gemcitabine and nab-paclitaxel for the treatment of pancreatic ductal adenocarcinoma
AS Azmi, HY Khan, I Muqbil, A Aboukameel, JE Neggers, D Daelemans, ...
Clinical Cancer Research 26 (6), 1338-1348, 2020
502020
Chemistry and bioactivity of boswellic acids and other terpenoids of the genus boswellia
A Al-Harrasi, H Hussain, R Csuk, HY Khan
Elsevier, 2018
412018
Mobilization of copper ions in human peripheral lymphocytes by catechins leading to oxidative DNA breakage: A structure activity study
M Farhan, A Zafar, S Chibber, HY Khan, H Arif, SM Hadi
Archives of biochemistry and biophysics 580, 31-40, 2015
402015
Targeting nuclear exporter protein XPO1/CRM1 in gastric cancer
R Sexton, Z Mahdi, R Chaudhury, R Beydoun, A Aboukameel, HY Khan, ...
International journal of molecular sciences 20 (19), 4826, 2019
372019
Calcium release-activated calcium (CRAC) channel inhibition suppresses pancreatic ductal adenocarcinoma cell proliferation and patient-derived tumor growth
HY Khan, GB Mpilla, R Sexton, S Viswanadha, KV Penmetsa, ...
Cancers 12 (3), 750, 2020
352020
Targeting XPO1 and PAK4 in 8505C anaplastic thyroid cancer cells: putative implications for overcoming lenvatinib therapy resistance
HY Khan, J Ge, M Nagasaka, A Aboukameel, G Mpilla, I Muqbil, ...
International Journal of Molecular Sciences 21 (1), 237, 2019
332019
Selinexor in combination with R-CHOP for frontline treatment of non-hodgkin lymphoma: results of a phase I study
EK Seymour, HY Khan, Y Li, M Chaker, I Muqbil, A Aboukameel, ...
Clinical Cancer Research 27 (12), 3307-3316, 2021
252021
Prooxidant anticancer activity of plant-derived polyphenolic compounds: An underappreciated phenomenon
HY Khan, SM Hadi, RM Mohammad, AS Azmi
Functional foods in cancer prevention and therapy, 221-236, 2020
242020
Apogossypolone, derivative of gossypol, mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage
H Zubair, HY Khan, MF Ullah, A Ahmad, D Wu, SM Hadi
European journal of pharmaceutical sciences 47 (1), 280-286, 2012
232012
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