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gian gaetano tartaglia
gian gaetano tartaglia
IIT (Sapienza / ICREA / CRG / University of Cambridge / University of Zurich)
Η διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα iit.it - Αρχική σελίδα
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ALS/FTD mutation-induced phase transition of FUS liquid droplets and reversible hydrogels into irreversible hydrogels impairs RNP granule function
T Murakami, S Qamar, JQ Lin, GSK Schierle, E Rees, A Miyashita, ...
Neuron 88 (4), 678-690, 2015
8732015
FUS phase separation is modulated by a molecular chaperone and methylation of arginine cation-π interactions
S Qamar, GZ Wang, SJ Randle, FS Ruggeri, JA Varela, JQ Lin, ...
Cell 173 (3), 720-734. e15, 2018
8682018
Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions
H Olzscha, SM Schermann, AC Woerner, S Pinkert, MH Hecht, ...
Cell 144 (1), 67-78, 2011
7982011
Mendelian randomization
E Birney
Cold Spring Harbor perspectives in medicine 12 (4), a041302, 2022
5782022
Metastability of native proteins and the phenomenon of amyloid formation
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, ...
Journal of the American Chemical Society 133 (36), 14160-14163, 2011
5142011
Prediction of aggregation-prone regions in structured proteins
GG Tartaglia, AP Pawar, S Campioni, CM Dobson, F Chiti, M Vendruscolo
Journal of molecular biology 380 (2), 425-436, 2008
5112008
DnaK functions as a central hub in the E. coli chaperone network
G Calloni, T Chen, SM Schermann, H Chang, P Genevaux, F Agostini, ...
Cell reports 1 (3), 251-264, 2012
4592012
Predicting protein associations with long noncoding RNAs
M Bellucci, F Agostini, M Masin, GG Tartaglia
Nature methods 8 (6), 444-445, 2011
3932011
The Zyggregator method for predicting protein aggregation propensities
GG Tartaglia, M Vendruscolo
Chemical Society Reviews 37 (7), 1395-1401, 2008
3772008
Life on the edge: a link between gene expression levels and aggregation rates of human proteins
GG Tartaglia, S Pechmann, CM Dobson, M Vendruscolo
Trends in biochemical sciences 32 (5), 204-206, 2007
3352007
Widespread aggregation and neurodegenerative diseases are associated with supersaturated proteins
P Ciryam, GG Tartaglia, RI Morimoto, CM Dobson, M Vendruscolo
Cell reports 5 (3), 781-790, 2013
2892013
catRAPID omics: a web server for large-scale prediction of protein–RNA interactions
F Agostini, A Zanzoni, P Klus, D Marchese, D Cirillo, GG Tartaglia
Bioinformatics 29 (22), 2928-2930, 2013
2872013
A concentration-dependent liquid phase separation can cause toxicity upon increased protein expression
B Bolognesi, NL Gotor, R Dhar, D Cirillo, M Baldrighi, GG Tartaglia, ...
Cell reports 16 (1), 222-231, 2016
2832016
Prediction of aggregation rate and aggregation‐prone segments in polypeptide sequences
GG Tartaglia, A Cavalli, R Pellarin, A Caflisch
Protein science 14 (10), 2723-2734, 2005
2382005
Systematic in vivo analysis of the intrinsic determinants of amyloid β pathogenicity
LM Luheshi, GG Tartaglia, AC Brorsson, AP Pawar, IE Watson, F Chiti, ...
PLoS biology 5 (11), e290, 2007
2282007
The role of aromaticity, exposed surface, and dipole moment in determining protein aggregation rates
GG Tartaglia, A Cavalli, R Pellarin, A Caflisch
Protein Science 13 (7), 1939-1941, 2004
2092004
Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19
L Gaziano, C Giambartolomei, AC Pereira, A Gaulton, DC Posner, ...
Nature medicine 27 (4), 668-676, 2021
1972021
Physicochemical principles that regulate the competition between functional and dysfunctional association of proteins
S Pechmann, ED Levy, GG Tartaglia, M Vendruscolo
Proceedings of the National Academy of Sciences 106 (25), 10159-10164, 2009
1802009
RNA structure drives interaction with proteins
N Sanchez de Groot, A Armaos, R Graña-Montes, M Alriquet, G Calloni, ...
Nature communications 10 (1), 3246, 2019
1702019
The mutational landscape of a prion-like domain
B Bolognesi, AJ Faure, M Seuma, JM Schmiedel, GG Tartaglia, B Lehner
Nature communications 10 (1), 4162, 2019
1492019
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