Indoleamine 2, 3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer GC Prendergast, C Smith, S Thomas, L Mandik-Nayak, L Laury-Kleintop, ... Cancer immunology, immunotherapy 63, 721-735, 2014 | 539 | 2014 |
IDO is a nodal pathogenic driver of lung cancer and metastasis development C Smith, MY Chang, KH Parker, DW Beury, JB DuHadaway, HE Flick, ... Cancer discovery 2 (8), 722-735, 2012 | 347 | 2012 |
Engagement of the antigen-receptor on immature murine B lymphocytes results in death by apoptosis. A Norvell, L Mandik, JG Monroe Journal of immunology (Baltimore, Md.: 1950) 154 (9), 4404-4413, 1995 | 295 | 1995 |
The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells S Seo, ML Fields, JL Buckler, AJ Reed, L Mandik-Nayak, SA Nish, ... Immunity 16 (4), 535-546, 2002 | 290 | 2002 |
Regulation of anti–double-stranded DNA B cells in nonautoimmune mice: localization to the T–B interface of the splenic follicle L Mandik-Nayak, A Bui, H Noorchashm, A Eaton, J Erikson The Journal of experimental medicine 186 (8), 1257-1267, 1997 | 231 | 1997 |
IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation R Metz, C Smith, JB DuHadaway, P Chandler, B Baban, LMF Merlo, ... International immunology 26 (7), 357-367, 2014 | 206 | 2014 |
DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes AL Bredemeyer, BA Helmink, CL Innes, B Calderon, LM McGinnis, ... Nature 456 (7223), 819-823, 2008 | 173 | 2008 |
MRL-lpr/lpr Mice Exhibit a Defect in Maintaining Developmental Arrest and Follicular Exclusion of Anti–double-stranded DNA B Cells L Mandik-Nayak, S Seo, C Sokol, KM Potts, A Bui, J Erikson The Journal of experimental medicine 189 (11), 1799-1814, 1999 | 162 | 1999 |
IDO2 in immunomodulation and autoimmune disease GC Prendergast, R Metz, AJ Muller, LMF Merlo, L Mandik-Nayak Frontiers in immunology 5, 585, 2014 | 150 | 2014 |
IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis LMF Merlo, E Pigott, JB DuHadaway, S Grabler, R Metz, GC Prendergast, ... The Journal of Immunology 192 (5), 2082-2090, 2014 | 126 | 2014 |
The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity GN Scott, J DuHadaway, E Pigott, N Ridge, GC Prendergast, AJ Muller, ... The Journal of Immunology 182 (12), 7509-7517, 2009 | 125 | 2009 |
Indoleamine 2, 3-dioxygenase as a modifier of pathogenic inflammation in cancer and other inflammation-associated diseases G C Prendergast, M Y Chang, L Mandik-Nayak, R Metz, A J Muller Current medicinal chemistry 18 (15), 2257-2262, 2011 | 116 | 2011 |
Characterization of anergic anti-DNA B cells: B cell anergy is a T cell-independent and potentially reversible process H Noorchashm, A Bui, HL Li, A Eaton, L Mandik-Nayak, C Sokol, KM Potts, ... International immunology 11 (5), 765-776, 1999 | 111 | 1999 |
Differential roles of IDO1 and IDO2 in T and B cell inflammatory immune responses LMF Merlo, JB DuHadaway, JD Montgomery, WD Peng, PJ Murray, ... Frontiers in immunology 11, 1861, 2020 | 106 | 2020 |
Despite ubiquitous autoantigen expression, arthritogenic autoantibody response initiates in the local lymph node L Mandik-Nayak, BT Wipke, FF Shih, ER Unanue, PM Allen Proceedings of the National Academy of Sciences 99 (22), 14368-14373, 2002 | 87 | 2002 |
Characterization of anti-single-stranded DNA B cells in a non-autoimmune background. KA Nguyen, L Mandik, A Bui, J Kavaler, A Norvell, JG Monroe, JH Roark, ... Journal of immunology (Baltimore, Md.: 1950) 159 (6), 2633-2644, 1997 | 82 | 1997 |
Massive Thymic Deletion Results in Systemic Autoimmunity through Elimination of CD4+ CD25+ T Regulatory Cells FF Shih, L Mandik-Nayak, BT Wipke, PM Allen The Journal of experimental medicine 199 (3), 323-335, 2004 | 78 | 2004 |
Functional consequences of the developmental arrest and follicular exclusion of anti-double-stranded DNA B cells L Mandik-Nayak, S Seo, A Eaton-Bassiri, D Allman, RR Hardy, J Erikson The Journal of Immunology 164 (3), 1161-1168, 2000 | 73 | 2000 |
Persistence of functionally compromised anti-double-stranded DNA B cells in the periphery of non-autoimmune mice. JH Roark, A Bui, KA Nguyen, L Mandik, J Erikson International immunology 9 (11), 1615-1626, 1997 | 71 | 1997 |
Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion AJ Muller, JB DuHadaway, MY Chang, A Ramalingam, E Sutanto-Ward, ... Cancer immunology, immunotherapy 59, 1655-1663, 2010 | 66 | 2010 |