| Modern advances in heterocyclic chemistry in drug discovery AP Taylor, RP Robinson, YM Fobian, DC Blakemore, LH Jones, O Fadeyi Organic & biomolecular chemistry 14 (28), 6611-6637, 2016 | 800 | 2016 |
| SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell stem cell 29 (2), 217-231. e8, 2022 | 215 | 2022 |
| Arylsulfonylamino hydroxamic acid derivatives RP Robinson, JP Rizzi US Patent 5,863,949, 1999 | 215 | 1999 |
| Rational targeting of active-site tyrosine residues using sulfonyl fluoride probes EC Hett, H Xu, KF Geoghegan, A Gopalsamy, RE Kyne Jr, CA Menard, ... ACS chemical biology 10 (4), 1094-1098, 2015 | 184 | 2015 |
| Recent advances in the synthetic chemistry of bicyclo [1.1. 1] pentane J Kanazawa, M Uchiyama Synlett 30 (01), 1-11, 2019 | 162 | 2019 |
| Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate … ML Vazquez, N Kaila, JW Strohbach, JD Trzupek, MF Brown, ... Journal of medicinal chemistry 61 (3), 1130-1152, 2018 | 157 | 2018 |
| Morphometric analysis of blood vessels in synovial membranes obtained from clinically affected and unaffected knee joints of patients with rheumatoid arthritis. O FitzGerald, M Soden, G Yanni, R Robinson, B Bresnihan Annals of the Rheumatic Diseases 50 (11), 792-796, 1991 | 157 | 1991 |
| Discovery of a clinical candidate from the structurally unique dioxa-bicyclo [3.2. 1] octane class of sodium-dependent glucose cotransporter 2 inhibitors V Mascitti, TS Maurer, RP Robinson, J Bian, CM Boustany-Kari, T Brandt, ... Journal of medicinal chemistry 54 (8), 2952-2960, 2011 | 140 | 2011 |
| Discovery of the Hemifumarate and (α-l-Alanyloxy)methyl Ether as Prodrugs of an Antirheumatic Oxindole: Prodrugs for the Enolic OH Group RP Robinson, LA Reiter, WE Barth, AM Campeta, K Cooper, BJ Cronin, ... Journal of medicinal chemistry 39 (1), 10-18, 1996 | 136 | 1996 |
| Covalent enzyme inhibition through fluorosulfate modification of a noncatalytic serine residue OO Fadeyi, LR Hoth, C Choi, X Feng, A Gopalsamy, EC Hett, RE Kyne Jr, ... ACS Chemical Biology 12 (8), 2015-2020, 2017 | 117 | 2017 |
| Visible-light-driven photocatalytic initiation of radical thiol–ene reactions using bismuth oxide OO Fadeyi, JJ Mousseau, Y Feng, C Allais, P Nuhant, MZ Chen, B Pierce, ... Organic letters 17 (23), 5756-5759, 2015 | 94 | 2015 |
| β-Lactams as building blocks in the synthesis of macrocyclic spermine and spermidine alkaloids HH Wasserman, H Matsuyama, RP Robinson Tetrahedron 58 (35), 7177-7190, 2002 | 80 | 2002 |
| The glucocorticoid receptor: molecular mechanism and new therapeutic opportunities L Buckbinder, RP Robinson Current Drug Targets-Inflammation & Allergy 1 (2), 127-136, 2002 | 78 | 2002 |
| Pyran-containing sulfonamide hydroxamic acids: potent MMP inhibitors that spare MMP-1 LA Reiter, RP Robinson, KF McClure, CS Jones, MR Reese, PG Mitchell, ... Bioorganic & medicinal chemistry letters 14 (13), 3389-3395, 2004 | 77 | 2004 |
| Total synthesis of (.+-.)-O-methylorantine HH Wasserman, RK Brunner, JD Buynak, CG Carter, T Oku, RP Robinson Journal of the American Chemical Society 107 (2), 519-521, 1985 | 76 | 1985 |
| Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ... Science 382 (6671), eabo7201, 2023 | 75 | 2023 |
| Preclinical species and human disposition of PF-04971729, a selective inhibitor of the sodium-dependent glucose cotransporter 2 and clinical candidate for the treatment of type … AS Kalgutkar, M Tugnait, T Zhu, E Kimoto, Z Miao, V Mascitti, X Yang, ... Drug metabolism and disposition 39 (9), 1609-1619, 2011 | 75 | 2011 |
| Identification of cyanamide-based Janus kinase 3 (JAK3) covalent inhibitors A Casimiro-Garcia, JI Trujillo, F Vajdos, B Juba, ME Banker, A Aulabaugh, ... Journal of Medicinal Chemistry 61 (23), 10665-10699, 2018 | 73 | 2018 |
| Aryloxyarylsulfonylamino hydroxamic acid derivatives RP Robinson US Patent 6,214,872, 2001 | 67 | 2001 |
| Potent pyrimidinetrione-based inhibitors of MMP-13 with enhanced selectivity over MMP-14 JA Blagg, MC Noe, LA Wolf-Gouveia, LA Reiter, ER Laird, SPP Chang, ... Bioorganic & medicinal chemistry letters 15 (7), 1807-1810, 2005 | 66 | 2005 |
