| Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells J Tan, X Yang, L Zhuang, X Jiang, W Chen, PL Lee, RKM Karuturi, ... Genes & development 21 (9), 1050-1063, 2007 | 1054 | 2007 |
| Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma A Jusakul, I Cutcutache, CH Yong, JQ Lim, MN Huang, N Padmanabhan, ... Cancer discovery 7 (10), 1116-1135, 2017 | 845 | 2017 |
| Oncogenic activation of the STAT3 pathway drives PD-L1 expression in natural killer/T-cell lymphoma TL Song, ML Nairismägi, Y Laurensia, JQ Lim, J Tan, ZM Li, WL Pang, ... Blood, The Journal of the American Society of Hematology 132 (11), 1146-1158, 2018 | 322 | 2018 |
| Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim Y Zhao, J Tan, L Zhuang, X Jiang, ET Liu, Q Yu Proceedings of the National Academy of Sciences 102 (44), 16090-16095, 2005 | 317 | 2005 |
| DACT3 is an epigenetic regulator of Wnt/β-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications X Jiang, J Tan, J Li, S Kivimäe, X Yang, L Zhuang, PL Lee, MTW Chan, ... Cancer cell 13 (6), 529-541, 2008 | 287 | 2008 |
| Genomic and transcriptomic profiling of combined hepatocellular and intrahepatic cholangiocarcinoma reveals distinct molecular subtypes R Xue, LU Chen, C Zhang, M Fujita, R Li, SM Yan, CK Ong, X Liao, Q Gao, ... Cancer cell 35 (6), 932-947. e8, 2019 | 238 | 2019 |
| Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma WK Lim, CK Ong, J Tan, AA Thike, CCY Ng, V Rajasegaran, SS Myint, ... Nature genetics 46 (8), 877-880, 2014 | 223 | 2014 |
| Genomic landscapes of breast fibroepithelial tumors J Tan, CK Ong, WK Lim, CCY Ng, AA Thike, LM Ng, V Rajasegaran, ... Nature genetics 47 (11), 1341-1345, 2015 | 219 | 2015 |
| The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor … TJ Seng, JSW Low, H Li, Y Cui, HK Goh, MLY Wong, G Srivastava, ... Oncogene 26 (6), 934-944, 2007 | 173 | 2007 |
| PDK1 signaling toward PLK1–MYC activation confers oncogenic transformation, tumor-initiating cell activation, and resistance to mTOR-targeted therapy J Tan, Z Li, PL Lee, P Guan, MY Aau, ST Lee, M Feng, CZ Lim, EYJ Lee, ... Cancer discovery 3 (10), 1156-1171, 2013 | 162* | 2013 |
| JAK-STAT and G-protein-coupled receptor signaling pathways are frequently altered in epitheliotropic intestinal T-cell lymphoma ML Nairismägi, J Tan, JQ Lim, S Nagarajan, CCY Ng, V Rajasegaran, ... Leukemia 30 (6), 1311-1319, 2016 | 156 | 2016 |
| Pharmacologic modulation of glycogen synthase kinase-3β promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells J Tan, L Zhuang, HS Leong, NG Iyer, ET Liu, Q Yu Cancer research 65 (19), 9012-9020, 2005 | 156 | 2005 |
| VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma X Yao, J Tan, KJ Lim, J Koh, WF Ooi, Z Li, D Huang, M Xing, YS Chan, ... Cancer discovery 7 (11), 1284-1305, 2017 | 146 | 2017 |
| B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer J Tan, PL Lee, Z Li, X Jiang, YC Lim, SC Hooi, Q Yu Cancer cell 18 (5), 459-471, 2010 | 138 | 2010 |
| The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/β-catenin signaling and silenced in common carcinomas L Li, J Ying, H Li, Y Zhang, X Shu, Y Fan, J Tan, Y Cao, SW Tsao, ... Oncogene 31 (34), 3901-3912, 2012 | 117 | 2012 |
| Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage Z Wu, ST Lee, Y Qiao, Z Li, PL Lee, YJ Lee, X Jiang, J Tan, M Aau, ... Cell Death & Differentiation 18 (11), 1771-1779, 2011 | 111 | 2011 |
| Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma JY Chan, JQ Lim, J Yeong, V Ravi, P Guan, A Boot, TKY Tay, ... The Journal of clinical investigation 130 (11), 5833-5846, 2020 | 86 | 2020 |
| Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitorinduced apoptosis through positive feedback regulation of E2F1 … J Tan, L Zhuang, X Jiang, KK Yang, KM Karuturi, Q Yu Journal of Biological Chemistry 281 (15), 10508-10515, 2006 | 83 | 2006 |
| MED12 is frequently mutated in breast phyllodes tumours: a study of 112 cases CCY Ng, J Tan, CK Ong, WK Lim, V Rajasegaran, NDM Nasir, JCT Lim, ... Journal of clinical pathology 68 (9), 685-691, 2015 | 82 | 2015 |
| Ribosomal protein S27-like, a p53-inducible modulator of cell fate in response to genotoxic stress J Li, J Tan, L Zhuang, B Banerjee, X Yang, JFL Chau, PL Lee, MP Hande, ... Cancer Research 67 (23), 11317-11326, 2007 | 76 | 2007 |
Patrick TanDuke-NUS Medical SchoolΗ διεύθυνση ηλεκτρονικού ταχυδρομείου έχει επαληθευτεί στον τομέα duke-nus.edu.sg
