Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts F Calvo, N Ege, A Grande-Garcia, S Hooper, RP Jenkins, SI Chaudhry, ... Nature cell biology 15 (6), 637-646, 2013 | 1477 | 2013 |
Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization Y del Pozo Martin, D Park, A Ramachandran, L Ombrato, F Calvo, ... Cell reports 13 (11), 2456-2469, 2015 | 247 | 2015 |
Genomic and transcriptomic determinants of therapy resistance and immune landscape evolution during anti-EGFR treatment in colorectal cancer A Woolston, K Khan, G Spain, LJ Barber, B Griffiths, R Gonzalez-Exposito, ... Cancer cell 36 (1), 35-50. e9, 2019 | 242 | 2019 |
Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness A Avgustinova, M Iravani, D Robertson, A Fearns, Q Gao, P Klingbeil, ... Nature communications 7 (1), 1-14, 2016 | 204 | 2016 |
Distinct utilization of effectors and biological outcomes resulting from site-specific Ras activation: Ras functions in lipid rafts and Golgi complex are dispensable for … D Matallanas, V Sanz-Moreno, I Arozarena, F Calvo, L Agudo-Ibánez, ... Molecular and cellular biology 26 (1), 100-116, 2006 | 153 | 2006 |
Distinct utilization of effectors and biological outcomes resulting from site-specific Ras activation: Ras functions in lipid rafts and Golgi complex are dispensable for … D Matallanas, V Sanz-Moreno, I Arozarena, F Calvo, L Agudo-Ibáñez, ... Molecular and cellular biology 26 (1), 100-116, 2006 | 153 | 2006 |
Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associated fibroblasts F Calvo, N Ferrari, R Ranftl, I Chicherova, ND Slaven, E Moeendarbary, ... Nature Research (part of Springer Nature), 2018 | 152* | 2018 |
Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts F Calvo, R Ranftl, S Hooper, AJ Farrugia, E Moeendarbary, A Bruckbauer, ... Cell reports 13 (12), 2699-2714, 2015 | 149 | 2015 |
Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors I Arozarena, D Matallanas, MT Berciano, V Sanz-Moreno, F Calvo, ... Molecular and cellular biology 24 (4), 1516-1530, 2004 | 122 | 2004 |
Cell communication networks in cancer invasion F Calvo, E Sahai Current opinion in cell biology 23 (5), 621-629, 2011 | 117 | 2011 |
ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastoma–lamin A complexes J Rodríguez, F Calvo, JM González, B Casar, V Andrés, P Crespo Journal of Cell Biology 191 (5), 967-979, 2010 | 102 | 2010 |
The Ras‐ERK pathway: Understanding site‐specific signaling provides hope of new anti‐tumor therapies F Calvo, L Agudo‐Ibáñez, P Crespo Bioessays 32 (5), 412-421, 2010 | 98 | 2010 |
RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation F Calvo, V Sanz-Moreno, L Agudo-Ibáñez, F Wallberg, E Sahai, ... Nature cell biology 13 (7), 819-826, 2011 | 97 | 2011 |
The Borg family of Cdc42 effector proteins Cdc42EP1–5 AJ Farrugia, F Calvo Biochemical Society Transactions 44 (6), 1709-1716, 2016 | 66 | 2016 |
Reactivation of p53 by a cytoskeletal sensor to control the balance between DNA damage and tumor dissemination C Herraiz, F Calvo, P Pandya, G Cantelli, I Rodriguez-Hernandez, ... JNCI: Journal of the National Cancer Institute 108 (1), 2016 | 66 | 2016 |
Ras, an Actor on Many Stages Posttranslational Modifications, Localization, and Site-Specified Events I Arozarena, F Calvo, P Crespo Genes & cancer 2 (3), 182-194, 2011 | 66 | 2011 |
CDC42EP5/BORG3 modulates SEPT9 to promote actomyosin function, migration, and invasion AJ Farrugia, J Rodríguez, JL Orgaz, M Lucas, V Sanz-Moreno, F Calvo Journal of Cell Biology 219 (9), 2020 | 64 | 2020 |
SREBP1 drives Keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer Y Perone, AJ Farrugia, A Rodríguez-Meira, B Győrffy, C Ion, A Uggetti, ... Nature communications 10 (1), 1-15, 2019 | 60 | 2019 |
Factors Secreted by Cancer-Associated Fibroblasts that Sustain Cancer Stem Properties in Head and Neck Squamous Carcinoma Cells as Potential Therapeutic Targets S Álvarez-Teijeiro, C García-Inclán, M Villaronga, P Casado, ... Cancers 10 (9), 334, 2018 | 59 | 2018 |
Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment AM Araujo, A Abaurrea, P Azcoaga, JI López-Velazco, S Manzano, ... The Journal of clinical investigation 132 (7), 2022 | 54 | 2022 |