| Enhanced prime editing systems by manipulating cellular determinants of editing outcomes PJ Chen, JA Hussmann, J Yan, F Knipping, P Ravisankar, PF Chen, ... Cell 184 (22), 5635-5652. e29, 2021 | 573 | 2021 |
| Improved ribosome-footprint and mRNA measurements provide insights into dynamics and regulation of yeast translation DE Weinberg, P Shah, SW Eichhorn, JA Hussmann, JB Plotkin, DP Bartel Cell reports 14 (7), 1787-1799, 2016 | 433 | 2016 |
| Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq JM Replogle, RA Saunders, AN Pogson, JA Hussmann, A Lenail, A Guna, ... Cell 185 (14), 2559-2575. e28, 2022 | 401 | 2022 |
| Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing JM Replogle, TM Norman, A Xu, JA Hussmann, J Chen, JZ Cogan, ... Nature biotechnology 38 (8), 954-961, 2020 | 346 | 2020 |
| High-throughput DNA sequencing errors are reduced by orders of magnitude using circle sequencing DI Lou, JA Hussmann, RM McBee, A Acevedo, R Andino, WH Press, ... Proceedings of the National Academy of Sciences 110 (49), 19872-19877, 2013 | 334 | 2013 |
| Ribosome Profiling: Global Views of Translation NT Ingolia, JA Hussmann, JS Weissman Cold Spring Harbor Perspectives in Biology, a032698, 2018 | 275 | 2018 |
| Understanding biases in ribosome profiling experiments reveals signatures of translation dynamics in yeast JA Hussmann, S Patchett, A Johnson, S Sawyer, WH Press PLoS genetics 11 (12), e1005732, 2015 | 254 | 2015 |
| The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins MJ Shurtleff, DN Itzhak, JA Hussmann, NTS Oakdale, EA Costa, ... eLife 7, e37018, 2018 | 223 | 2018 |
| Efficient C·G-to-G·C base editors developed using CRISPRi screens, target-library analysis, and machine learning LW Koblan, M Arbab, MW Shen, JA Hussmann, AV Anzalone, JL Doman, ... Nature Biotechnology, 2021 | 188 | 2021 |
| CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides KK Kostova, KL Hickey, BA Osuna, JA Hussmann, A Frost, DE Weinberg, ... Science 357 (6349), 414-417, 2017 | 151 | 2017 |
| Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs M Jost, DA Santos, RA Saunders, MA Horlbeck, JS Hawkins, SM Scaria, ... Nature Biotechnology 38 (3), 355-364, 2020 | 149 | 2020 |
| Mapping the Genetic Landscape of DNA Double-strand Break Repair JA Hussmann, J Ling, P Ravisankar, J Yan, A Cirincione, A Xu, ... Cell 184 (22), 5653-5669.e25, 2021 | 146 | 2021 |
| GIGYF2 and 4EHP Inhibit translation initiation of defective messenger RNAs to assist ribosome-associated quality control KL Hickey, K Dickson, JZ Cogan, JM Replogle, M Schoof, KN D’Orazio, ... Molecular Cell, 2020 | 142 | 2020 |
| Massively parallel biophysical analysis of CRISPR-Cas complexes on next generation sequencing chips C Jung, JA Hawkins, SK Jones Jr, Y Xiao, JR Rybarski, KE Dillard, ... Cell 170 (1), 35-47. e13, 2017 | 116 | 2017 |
| Inference of single-cell phylogenies from lineage tracing data using Cassiopeia MG Jones, A Khodaverdian, JJ Quinn, MM Chan, JA Hussmann, R Wang, ... Genome Biology 21, 1-27, 2020 | 103 | 2020 |
| Deciphering cell states and genealogies of human hematopoiesis C Weng, F Yu, D Yang, M Poeschla, LA Liggett, MG Jones, X Qiu, ... Nature, 1-3, 2024 | 58 | 2024 |
| Deep profiling reveals substantial heterogeneity of integration outcomes in CRISPR knock-in experiments H Canaj, JA Hussmann, H Li, KA Beckman, L Goodrich, NH Cho, YJ Li, ... bioRxiv, 841098, 2019 | 55 | 2019 |
| Regulation of translation by methylation multiplicity of 18S rRNA K Liu, DA Santos, JA Hussmann, Y Wang, BM Sutter, JS Weissman, ... Cell Reports 34 (10), 108825, 2021 | 30 | 2021 |
| CRISPR-based functional genomics in human dendritic cells M Jost, AN Jacobson, JA Hussmann, G Cirolia, MA Fischbach, ... Elife 10, e65856, 2021 | 27 | 2021 |
| Rapid deployment of SARS-CoV-2 testing: The CLIAHUB ED Crawford, I Acosta, V Ahyong, EC Anderson, S Arevalo, D Asarnow, ... PLoS Pathogens 16 (10), e1008966, 2020 | 23 | 2020 |
