| A new antibiotic selectively kills Gram-negative pathogens Y Imai, KJ Meyer, A Iinishi, Q Favre-Godal, R Green, S Manuse, M Caboni, ... Nature 576 (7787), 459-464, 2019 | 676 | 2019 |
| Mechanism-of-action classification of antibiotics by global transcriptome profiling A O’Rourke, S Beyhan, Y Choi, P Morales, AP Chan, JL Espinoza, ... Antimicrobial agents and chemotherapy 64 (3), 10.1128/aac. 01207-19, 2020 | 110 | 2020 |
| Gram-scale total synthesis of teixobactin promoting binding mode study and discovery of more potent antibiotics Y Zong, F Fang, KJ Meyer, L Wang, Z Ni, H Gao, K Lewis, J Zhang, Y Rao Nature communications 10 (1), 3268, 2019 | 48 | 2019 |
| Developing Equipotent Teixobactin Analogues against Drug-Resistant Bacteria and Discovering a Hydrophobic Interaction between Lipid II and Teixobactin Y Zong, X Sun, H Gao, KJ Meyer, K Lewis, Y Rao Journal of medicinal chemistry 61 (8), 3409-3421, 2018 | 42 | 2018 |
| Potent antitrypanosomal activities of heat shock protein 90 inhibitors in vitro and in vivo KJ Meyer, TA Shapiro The Journal of infectious diseases 208 (3), 489-499, 2013 | 42 | 2013 |
| Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation NM Revie, KR Iyer, ME Maxson, J Zhang, S Yan, CM Fernandes, ... Nature Communications 13 (1), 1-20, 2022 | 32 | 2022 |
| Predicting antimicrobial mechanism-of-action from transcriptomes: A generalizable explainable artificial intelligence approach JL Espinoza, CL Dupont, A O’Rourke, S Beyhan, P Morales, A Spoering, ... PLOS Computational Biology 17 (3), e1008857, 2021 | 30 | 2021 |
| Mitochondrial genome-knockout cells demonstrate a dual mechanism of action for the electron transport complex I inhibitor mycothiazole KJ Meyer, AJ Singh, A Cameron, AS Tan, DC Leahy, D O’Sullivan, ... Marine drugs 10 (4), 900-917, 2012 | 17 | 2012 |
| Biology and applications of co-produced, synergistic antimicrobials from environmental bacteria KJ Meyer, JR Nodwell Nature Microbiology 6 (9), 1118-1128, 2021 | 15 | 2021 |
| Pulse Dosing of Antibiotic Enhances Killing of a Staphylococcus aureus Biofilm KJ Meyer, HB Taylor, J Seidel, MF Gates, K Lewis Frontiers in microbiology 11, 596227, 2020 | 12 | 2020 |
| Model system identifies kinetic driver of Hsp90 inhibitor activity against African trypanosomes and Plasmodium falciparum KJ Meyer, E Caton, TA Shapiro Antimicrobial agents and chemotherapy 62 (8), 10.1128/aac. 00056-18, 2018 | 11 | 2018 |
| Optimal kinetic exposures for classic and candidate antitrypanosomals KJ Meyer, DJ Meyers, TA Shapiro Journal of Antimicrobial Chemotherapy 74 (8), 2303-2310, 2019 | 8 | 2019 |
| Analogs of N′-hydroxy-N-(4H, 5H-naphtho [1, 2-d] thiazol-2-yl) methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases S Bhat, O Olaleye, KJ Meyer, W Shi, Y Zhang, JO Liu Bioorganic & medicinal chemistry 20 (14), 4507-4513, 2012 | 8 | 2012 |
| Cytosolic and mitochondrial Hsp90 in cytokinesis, mitochondrial DNA replication, and drug action in trypanosoma brucei KJ Meyer, TA Shapiro Antimicrobial agents and chemotherapy 65 (11), 10.1128/aac. 00632-21, 2021 | 6 | 2021 |
| Streptomyces extracellular vesicles are a broad and permissive antimicrobial packaging and delivery system KJ Meyer, JR Nodwell Journal of Bacteriology 206 (3), e00325-23, 2024 | 5 | 2024 |
| High-throughput chemical screen identifies a 2, 5-disubstituted pyridine as an inhibitor of Candida albicans Erg11 AC Du Bois, A Xue, C Pham, NM Revie, KJ Meyer, Y Yashiroda, C Boone, ... Msphere 7 (3), e00075-22, 2022 | 5 | 2022 |
| Phosphatidylethanolamine is a phagocytic ligand implicated in the binding and removal of microbial extracellular vesicles A Kavianpour, KJ Meyer, T Le, PE Marques, JR Nodwell, SA Freeman bioRxiv, 2024.11. 18.624161, 2024 | | 2024 |
| Compounds with Antimicrobial Properties K Lewis, Y Imai, Q Favre-Godal, A Iinishi, K Meyer US Patent App. 18/056,346, 2023 | | 2023 |
| Isolated darobactin A analog compounds and compositions thereof K Lewis, Y Imai, Q Favre-Godal, A Iinishi, K Meyer US Patent 11,535,648, 2022 | | 2022 |
| Enhanced killing of in vitro Staphylococcus aureus biofilms by periodic dosing of oxacillin KJ Meyer, HB Taylor, JA Seidel, MF Gates, K Lewis CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 99 (11), S8-S8, 2021 | | 2021 |
Kim LewisUniversity Distinguished Professor, Northeastern UniversityVerified email at neu.edu
