| Next-generation personalised medicine for high-risk paediatric cancer patients–The INFORM pilot study BC Worst, CM van Tilburg, GP Balasubramanian, P Fiesel, R Witt, ... European journal of cancer 65, 91-101, 2016 | 344 | 2016 |
| A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study JJ Swen, CH van der Wouden, LEN Manson, H Abdullah-Koolmees, ... The Lancet 401 (10374), 347-356, 2023 | 332 | 2023 |
| The pediatric precision oncology INFORM registry: clinical outcome and benefit for patients with very high-evidence targets CM Van Tilburg, E Pfaff, KW Pajtler, KPS Langenberg, P Fiesel, BC Jones, ... Cancer discovery 11 (11), 2764-2779, 2021 | 190 | 2021 |
| Genetic variation in human drug-related genes CPI Schärfe, R Tremmel, M Schwab, O Kohlbacher, DS Marks Genome medicine 9, 1-15, 2017 | 137 | 2017 |
| Genetics, epigenetics, and regulation of drug‐metabolizing cytochrome P450 enzymes UM Zanger, K Klein, M Thomas, JK Rieger, R Tremmel, BA Kandel, ... Clinical Pharmacology & Therapeutics 95 (3), 258-261, 2014 | 111 | 2014 |
| Polymorphic Variation in TPMT Is the Principal Determinant of TPMT Phenotype: A Meta‐Analysis of Three Genome‐Wide Association Studies R Tamm, R Mägi, R Tremmel, S Winter, E Mihailov, A Smid, A Möricke, ... Clinical Pharmacology & Therapeutics 101 (5), 684-695, 2017 | 51 | 2017 |
| A new panel-based next-generation sequencing method for ADME genes reveals novel associations of common and rare variants with expression in a human liver cohort K Klein, R Tremmel, S Winter, S Fehr, F Battke, T Scheurenbrand, ... Frontiers in Genetics 10, 7, 2019 | 49 | 2019 |
| Methyleugenol DNA adducts in human liver are associated with SULT1A1 copy number variations and expression levels R Tremmel, K Herrmann, W Engst, W Meinl, K Klein, H Glatt, UM Zanger Archives of toxicology 91, 3329-3339, 2017 | 41 | 2017 |
| Pharmacogenomics decision support in the U-PGx project: results and advice from clinical implementation across seven European countries K Blagec, JJ Swen, R Koopmann, KC Cheung, ... PloS one 17 (6), e0268534, 2022 | 37 | 2022 |
| Challenges and opportunities associated with rare-variant pharmacogenomics Y Zhou, R Tremmel, E Schaeffeler, M Schwab, VM Lauschke Trends in pharmacological sciences 43 (10), 852-865, 2022 | 31 | 2022 |
| The Impact of CYP3A4*22 on Tacrolimus Pharmacokinetics and Outcome in Clinical Practice at a Single Kidney Transplant Center E Abdel-Kahaar, S Winter, R Tremmel, E Schaeffeler, CJ Olbricht, ... Frontiers in genetics 10, 871, 2019 | 28 | 2019 |
| Identification of cardiomyopathy-associated circulating miRNA biomarkers in muscular dystrophy female carriers using a complementary cardiac imaging and plasma profiling approach A Florian, A Patrascu, R Tremmel, S Rösch, U Sechtem, M Schwab, ... Frontiers in Physiology 9, 1770, 2018 | 28 | 2018 |
| HTCA: a database with an in-depth characterization of the single-cell human transcriptome L Pan, S Shan, R Tremmel, W Li, Z Liao, H Shi, Q Chen, X Zhang, X Li Nucleic Acids Research 51 (D1), D1019-D1028, 2023 | 20 | 2023 |
| Cross‐Ancestry Genome‐Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations CC Khor, S Winter, N Sutiman, TE Mürdter, S Chen, JSL Lim, Z Li, J Li, ... Clinical Pharmacology & Therapeutics 113 (3), 712-723, 2023 | 18 | 2023 |
| Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression R Tremmel, K Klein, F Battke, S Fehr, S Winter, T Scheurenbrand, ... Human genetics 139, 137-149, 2020 | 17 | 2020 |
| α2-Adrenergic receptor in liver fibrosis: implications for the adrenoblocker mesedin UA Schwinghammer, MM Melkonyan, L Hunanyan, R Tremmel, ... Cells 9 (2), 456, 2020 | 16 | 2020 |
| Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1 R Tremmel, K Klein, S Winter, E Schaeffeler, UM Zanger The pharmacogenomics journal 16 (6), 551-558, 2016 | 15 | 2016 |
| Association between CYP2E1 polymorphisms and risk of differentiated thyroid carcinoma L Pellé, M Cipollini, R Tremmel, C Romei, G Figlioli, F Gemignani, ... Archives of toxicology, 1-11, 2016 | 15 | 2016 |
| Antifibrotic effects of amyloid-beta and its loss in cirrhotic liver GH Buniatian, R Weiskirchen, TS Weiss, U Schwinghammer, M Fritz, ... Cells 9 (2), 452, 2020 | 14 | 2020 |
| Single Cell Atlas: a single-cell multi-omics human cell encyclopedia L Pan, P Parini, R Tremmel, J Loscalzo, VM Lauschke, BA Maron, P Paci, ... Genome Biology 25 (1), 104, 2024 | 11 | 2024 |
