Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling CB Vaegter, P Jansen, AW Fjorback, S Glerup, S Skeldal, M Kjolby, ... Nature neuroscience 14 (1), 54-61, 2011 | 224 | 2011 |
The hypercholesterolemia-risk gene SORT1 facilitates PCSK9 secretion C Gustafsen, M Kjolby, M Nyegaard, M Mattheisen, J Lundhede, ... Cell metabolism 19 (2), 310-318, 2014 | 202 | 2014 |
APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1 M Tachibana, ML Holm, CC Liu, M Shinohara, T Aikawa, H Oue, ... The Journal of clinical investigation 129 (3), 1272-1277, 2019 | 151 | 2019 |
Sortilin and SorLA display distinct roles in processing and trafficking of amyloid precursor protein C Gustafsen, S Glerup, LT Pallesen, D Olsen, OM Andersen, A Nykjær, ... Journal of Neuroscience 33 (1), 64-71, 2013 | 121 | 2013 |
Heparan sulfate proteoglycans present PCSK9 to the LDL receptor C Gustafsen, D Olsen, J Vilstrup, S Lund, A Reinhardt, N Wellner, ... Nature communications 8 (1), 503, 2017 | 112 | 2017 |
Physiological and therapeutic regulation of PCSK9 activity in cardiovascular disease S Glerup, R Schulz, U Laufs, KD Schlüter Basic research in cardiology 112, 1-23, 2017 | 101 | 2017 |
SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia S Glerup, D Olsen, CB Vaegter, C Gustafsen, SS Sjoegaard, G Hermey, ... Neuron 82 (5), 1074-1087, 2014 | 100 | 2014 |
SorCS2 is required for BDNF-dependent plasticity in the hippocampus S Glerup, U Bolcho, S Mølgaard, S Bøggild, CB Vaegter, AH Smith, ... Molecular psychiatry 21 (12), 1740-1751, 2016 | 98 | 2016 |
Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction T Breiderhoff, GB Christiansen, LT Pallesen, C Vaegter, A Nykjaer, ... PloS one 8 (9), e75006, 2013 | 98 | 2013 |
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking SC Klinger, S Glerup, MK Raarup, MC Mari, M Nyegaard, G Koster, ... Journal of cell science 124 (7), 1095-1105, 2011 | 93 | 2011 |
Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model P Bøttger, S Glerup, B Gesslein, NB Illarionova, TJ Isaksen, A Heuck, ... Scientific Reports 6 (1), 22047, 2016 | 87 | 2016 |
Mapping of the interaction site between sortilin and the p75 neurotrophin receptor reveals a regulatory role for the sortilin intracellular domain in p75 neurotrophin receptor … S Skeldal, AM Sykes, S Glerup, D Matusica, N Palstra, H Autio, Z Boskovic, ... Journal of Biological Chemistry 287 (52), 43798-43809, 2012 | 74 | 2012 |
SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET S Glerup, M Lume, D Olsen, JR Nyengaard, CB Vaegter, C Gustafsen, ... Cell reports 3 (1), 186-199, 2013 | 72 | 2013 |
Temporal course of pregnancy-associated plasma protein-A in angioplasty-treated ST-elevation myocardial infarction patients and potential significance of concomitant heparin … CJ Terkelsen, C Oxvig, BL Nørgaard, S Glerup, TS Poulsen, JF Lassen, ... The American journal of cardiology 103 (1), 29-35, 2009 | 63 | 2009 |
Proteinase inhibition by proform of eosinophil major basic protein (pro-MBP) is a multistep process of intra-and intermolecular disulfide rearrangements S Glerup, HB Boldt, MT Overgaard, L Sottrup-Jensen, LC Giudice, ... Journal of Biological Chemistry 280 (11), 9823-9832, 2005 | 53 | 2005 |
Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF HN Buttenschøn, D Demontis, M Kaas, B Elfving, S Mølgaard, ... Translational psychiatry 5 (11), e677-e677, 2015 | 50 | 2015 |
Sortilins in neurotrophic factor signaling S Glerup, A Nykjaer, CB Vægter Neurotrophic factors, 165-189, 2014 | 50 | 2014 |
Targeting PCSK9 to tackle cardiovascular disease S Hummelgaard, JP Vilstrup, C Gustafsen, S Glerup, K Weyer Pharmacology & Therapeutics 249, 108480, 2023 | 45 | 2023 |
Inhibition of proteolysis by the proform of eosinophil major basic protein (proMBP) requires covalent binding to its target proteinase MT Overgaard, S Glerup, HB Boldt, V Rodacker, IM Olsen, M Christiansen, ... FEBS letters 560 (1-3), 147-152, 2004 | 42 | 2004 |
Cognitive deficits caused by a disease-mutation in the α3 Na+/K+-ATPase isoform TH Holm, TJ Isaksen, S Glerup, A Heuck, P Bøttger, EM Füchtbauer, ... Scientific reports 6 (1), 31972, 2016 | 40 | 2016 |