| Structure of the adenosine-bound human adenosine A1 receptor–Gi complex CJ Draper-Joyce, M Khoshouei, DM Thal, YL Liang, ATN Nguyen, ... Nature 558 (7711), 559-563, 2018 | 344 | 2018 |
| Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia CJ Draper-Joyce, R Bhola, J Wang, A Bhattarai, ATN Nguyen, ... Nature 597 (7877), 571-576, 2021 | 128 | 2021 |
| A new mechanism of allostery in a G protein–coupled receptor dimer JR Lane, P Donthamsetti, J Shonberg, CJ Draper-Joyce, S Dentry, ... Nature chemical biology 10 (9), 745-752, 2014 | 128 | 2014 |
| Rules of engagement: GPCRs and G proteins A Glukhova, CJ Draper-Joyce, RK Sunahara, A Christopoulos, D Wootten, ... ACS pharmacology & translational science 1 (2), 73-83, 2018 | 120 | 2018 |
| Dominant negative G proteins enhance formation and purification of agonist-GPCR-G protein complexes for structure determination YL Liang, P Zhao, C Draper-Joyce, JA Baltos, A Glukhova, TT Truong, ... ACS pharmacology & translational science 1 (1), 12-20, 2018 | 106 | 2018 |
| Recent advances in the determination of G protein-coupled receptor structures DM Thal, Z Vuckovic, CJ Draper-Joyce, YL Liang, A Glukhova, ... Current opinion in structural biology 51, 28-34, 2018 | 65 | 2018 |
| Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D2 Receptor Through Fragmentation of a Bitopic Ligand SN Mistry, J Shonberg, CJ Draper-Joyce, C Klein Herenbrink, M Michino, ... Journal of medicinal chemistry 58 (17), 6819-6843, 2015 | 57 | 2015 |
| Structure–Activity Study of N-((trans)-4-(2-(7-Cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)-1H-indole-2-carboxamide (SB269652), a Bitopic Ligand That Acts as a … J Shonberg, C Draper-Joyce, SN Mistry, A Christopoulos, PJ Scammells, ... Journal of Medicinal Chemistry 58 (13), 5287-5307, 2015 | 45 | 2015 |
| The structural determinants of the bitopic binding mode of a negative allosteric modulator of the dopamine D2 receptor CJ Draper-Joyce, M Michino, RK Verma, CK Herenbrink, J Shonberg, ... Biochemical pharmacology 148, 315-328, 2018 | 32 | 2018 |
| Molecular determinants of the intrinsic efficacy of the antipsychotic aripiprazole C Klein Herenbrink, R Verma, HD Lim, A Kopinathan, A Keen, J Shonberg, ... ACS chemical biology 14 (8), 1780-1792, 2019 | 24 | 2019 |
| Conformational Transitions and the Activation of Heterotrimeric G Proteins by G Protein-Coupled Receptors C Draper-Joyce, SGB Furness ACS Pharmacology & Translational Science 2 (4), 285-290, 2019 | 18 | 2019 |
| Subtle Modifications to the Indole-2-carboxamide Motif of the Negative Allosteric Modulator N-((trans)-4-(2-(7-Cyano-3, 4-dihydroisoquinolin-2 (1 H)-yl) ethyl) cyclohexyl)-1 H … A Kopinathan, C Draper-Joyce, M Szabo, A Christopoulos, PJ Scammells, ... Journal of Medicinal Chemistry 62 (1), 371-377, 2018 | 17 | 2018 |
| The action of a negative allosteric modulator at the dopamine D2 receptor is dependent upon sodium ions CJ Draper-Joyce, RK Verma, M Michino, J Shonberg, A Kopinathan, ... Scientific Reports 8 (1), 1208, 2018 | 17 | 2018 |
| Structural insights into the unique modes of relaxin-binding and tethered-agonist mediated activation of RXFP1 and RXFP2 A Sethi, S Bruell, T Ryan, F Yan, MH Tanipour, YF Mok, C Draper-Joyce, ... Journal of Molecular Biology 433 (21), 167217, 2021 | 11 | 2021 |
| Positive allosteric modulation of a GPCR ternary complex WAC Burger, CJ Draper-Joyce, C Valant, A Christopoulos, DM Thal Science Advances 10 (37), eadp7040, 2024 | 3 | 2024 |
| Strength in numbers—an arrestin interaction code CJ Draper-Joyce, A Christopoulos Nature Structural & Molecular Biology 25 (6), 437-439, 2018 | | 2018 |