| Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles ME Davis, JE Zuckerman, CHJ Choi, D Seligson, A Tolcher, CA Alabi, ... Nature 464 (7291), 1067-1070, 2010 | 3032 | 2010 |
| Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis W Zhou, MY Fong, Y Min, G Somlo, L Liu, MR Palomares, Y Yu, A Chow, ... Cancer cell 25 (4), 501-515, 2014 | 1566 | 2014 |
| NCCN clinical practice guidelines in oncology: hepatobiliary cancers. AB Benson 3rd, TA Abrams, E Ben-Josef, PM Bloomston, JF Botha, ... Journal of the National Comprehensive Cancer Network: JNCCN 7 (4), 350-391, 2009 | 592 | 2009 |
| Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor F Yang, X Huang, T Yi, Y Yen, DD Moore, W Huang Cancer research 67 (3), 863-867, 2007 | 541 | 2007 |
| Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA JE Zuckerman, I Gritli, A Tolcher, JD Heidel, D Lim, R Morgan, ... Proceedings of the National Academy of Sciences 111 (31), 11449-11454, 2014 | 426 | 2014 |
| Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma T Chen, G Xie, X Wang, J Fan, Y Qiu, X Zheng, X Qi, Y Cao, M Su, ... Molecular & Cellular Proteomics 10 (7), 2011 | 401 | 2011 |
| Enabling technologies for personalized and precision medicine D Ho, SR Quake, ERB McCabe, WJ Chng, EK Chow, X Ding, BD Gelb, ... Trends in biotechnology 38 (5), 497-518, 2020 | 365 | 2020 |
| Ribonucleotide reductase inhibitors and future drug design J Shao, B Zhou, B Chu, Y Yen Current cancer drug targets 6 (5), 409-431, 2006 | 355 | 2006 |
| A subpopulation of CD133+ cancer stem-like cells characterized in human oral squamous cell carcinoma confer resistance to chemotherapy Q Zhang, S Shi, Y Yen, J Brown, JQ Ta, AD Le Cancer letters 289 (2), 151-160, 2010 | 353 | 2010 |
| A phase II study of lapatinib in patients with advanced biliary tree and hepatocellular cancer RK Ramanathan, CP Belani, DA Singh, M Tanaka, HJ Lenz, Y Yen, ... Cancer chemotherapy and pharmacology 64, 777-783, 2009 | 349 | 2009 |
| FZD7 has a critical role in cell proliferation in triple negative breast cancer L Yang, X Wu, Y Wang, K Zhang, J Wu, YC Yuan, X Deng, L Chen, ... Oncogene 30 (43), 4437-4446, 2011 | 331 | 2011 |
| Machine learning–based radiomics for molecular subtyping of gliomas CF Lu, FT Hsu, KLC Hsieh, YCJ Kao, SJ Cheng, JBK Hsu, PH Tsai, ... Clinical Cancer Research 24 (18), 4429-4436, 2018 | 308 | 2018 |
| Overexpression of ribonucleotide reductase as a mechanism of resistance to 2, 2-difluorodeoxycytidine in the human KB cancer cell line YG Goan, B Zhou, E Hu, S Mi, Y Yen Cancer research 59 (17), 4204-4207, 1999 | 286 | 1999 |
| De novo sequencing of circulating miRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer X Wu, G Somlo, Y Yu, MR Palomares, AX Li, W Zhou, A Chow, Y Yen, ... Journal of translational medicine 10, 1-10, 2012 | 279 | 2012 |
| Immunohistochemical staining in the diagnosis of pancreatobiliary and ampulla of Vater adenocarcinoma: application of CDX2, CK17, MUC1, and MUC2 PG Chu, RE Schwarz, SK Lau, Y Yen, LM Weiss The American journal of surgical pathology 29 (3), 359-367, 2005 | 244 | 2005 |
| First-in-human phase 1/2a trial of CRLX101, a cyclodextrin-containing polymer-camptothecin nanopharmaceutical in patients with advanced solid tumor malignancies GJ Weiss, J Chao, JD Neidhart, RK Ramanathan, D Bassett, JA Neidhart, ... Investigational new drugs 31, 986-1000, 2013 | 228 | 2013 |
| A Ferrous-Triapine complex mediates formation of reactive oxygen species that inactivate human ribonucleotide reductase J Shao, B Zhou, AJ Di Bilio, L Zhu, T Wang, C Qi, J Shih, Y Yen Molecular cancer therapeutics 5 (3), 586-592, 2006 | 217 | 2006 |
| Overexpression of HMGA2 promotes metastasis and impacts survival of colorectal cancers X Wang, X Liu, AYJ Li, L Chen, L Lai, HH Lin, S Hu, L Yao, J Peng, ... Clinical Cancer Research 17 (8), 2570-2580, 2011 | 213 | 2011 |
| Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression X Li, YK Lee, JC Jeng, Y Yen, DC Schultz, HM Shih, DK Ann Journal of Biological Chemistry 282 (50), 36177-36189, 2007 | 208 | 2007 |
| Potent siRNA Inhibitors of Ribonucleotide Reductase Subunit RRM2 Reduce Cell Proliferation In vitro and In vivo JD Heidel, JYC Liu, Y Yen, B Zhou, BSE Heale, JJ Rossi, DW Bartlett, ... Clinical Cancer Research 13 (7), 2207-2215, 2007 | 200 | 2007 |