Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10+ 16 splice-site mutation in MAPT T Sposito, E Preza, CJ Mahoney, N Setó-Salvia, NS Ryan, HR Morris, ... Human molecular genetics 24 (18), 5260-5269, 2015 | 183 | 2015 |
The evolving (epi) genetic landscape of pancreatic neuroendocrine tumours CP Pipinikas, AM Berner, T Sposito, C Thirlwell Endocrine-related cancer 26 (9), R519-R544, 2019 | 52 | 2019 |
Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons L Ritchie, R Tate, LH Chamberlain, G Robertson, M Zagnoni, T Sposito, ... Neuropharmacology 135, 1-10, 2018 | 22 | 2018 |
Aberrant chromatin landscape following loss of the H3. 3 chaperone Daxx in haematopoietic precursors leads to Pu. 1-mediated neutrophilia and inflammation JP Gerber, J Russ, V Chandrasekar, N Offermann, HM Lee, S Spear, ... Nature cell biology 23 (12), 1224-1239, 2021 | 14 | 2021 |
The PanNET-related histone H3. 3 chaperone Daxx regulates lineage specification and tissue homeostasis in the pancreas T Sposito, MSN Tu, GA Rutter, M Novelli, C Thirlwell, P Salomoni Cancer Research 79 (13_Supplement), 5294-5294, 2019 | 1 | 2019 |
Exploring ADAR1 dependencies in breast cancer brain-metastases T Sposito, EE Klacking, AW Ruiz, J Pham, C Jamieson Cancer Research 84 (6_Supplement), 2767-2767, 2024 | | 2024 |
Author Correction: Aberrant chromatin landscape following loss of the H3. 3 chaperone Daxx in haematopoietic precursors leads to Pu. 1-mediated neutrophilia and inflammation JP Gerber, J Russ, V Chandrasekar, N Offermann, HM Lee, S Spear, ... Nature Cell Biology 24 (1), 123-123, 2022 | | 2022 |
Histone replacement in cancer: dissecting the role of H3. 3 chaperone DAXX in pancreatic tumorigenesis T Sposito UCL (University College London), 2020 | | 2020 |
Histone Replacement in Cancer: Dissecting the Role of H3. 3 Chaperones in Pancreatic Tumorigenesis T Sposito, CN Tu, C Thirlwell, P Salomoni NEUROENDOCRINOLOGY 106, 54-54, 2018 | | 2018 |
Dementia on a chip: monitoring synaptic dysfunction of patient derived human neurons G Robertson, T Sposito, S Wray, J Hardy, TJ Bushell, M Zagnoni Chemical and Biological Microsystems Society, 2016 | | 2016 |
Developmental regulation of tau splicing and phosphorylation is conserved in iPSC-neurons and disrupted by the 10+ 16 intronic mutation in MAPT T Sposito, E Preza, A Alatza, C Mahoney, T Bushell, M Zagnoni, T Kunath, ... JOURNAL OF NEUROCHEMISTRY 138, 413-413, 2016 | | 2016 |
Human stem cell models of tauopathy T Sposito, E Preza, C Mahoney, N Ryan, N Seto-Salvia, C Arber, ... NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 42, 14-14, 2016 | | 2016 |
ASSOCIATION STUDIES ARTICLES R Shaheen, A Almoisheer, E Faqeih, Z Babay, D Monies, N Tassan, ... Human Molecular Genetics 24 (18), 2015 | | 2015 |