Metabolism and functions of docosahexaenoic acid‐containing membrane glycerophospholipids D Hishikawa, WJ Valentine, Y Iizuka‐Hishikawa, H Shindou, T Shimizu FEBS letters 591 (18), 2730-2744, 2017 | 147 | 2017 |
The lysophosphatidic acid type 2 receptor is required for protection against radiation-induced intestinal injury W Deng, E Shuyu, R Tsukahara, WJ Valentine, G Durgam, V Gududuru, ... Gastroenterology 132 (5), 1834-1851, 2007 | 142 | 2007 |
Different residues mediate recognition of 1-O-oleyllysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor γ T Tsukahara, R Tsukahara, S Yasuda, N Makarova, WJ Valentine, ... Journal of Biological Chemistry 281 (6), 3398-3407, 2006 | 103 | 2006 |
Update and nomenclature proposal for mammalian lysophospholipid acyltransferases, which create membrane phospholipid diversity WJ Valentine, K Yanagida, H Kawana, N Kono, NN Noda, J Aoki, ... Journal of Biological Chemistry 298 (1), 2022 | 78 | 2022 |
Lysophosphatidic acid-induced platelet shape change revealed through LPA1–5 receptor-selective probes and albumin AL Khandoga, AL Khandoga, Y Fujiwara, P Goyal, D Pandey, ... Platelets 19 (6), 415-427, 2008 | 69 | 2008 |
(S)-FTY720-vinylphosphonate, an analogue of the immunosuppressive agent FTY720, is a pan-antagonist of sphingosine 1-phosphate GPCR signaling and inhibits autotaxin activity WJ Valentine, GN Kiss, J Liu, E Shuyu, M Gotoh, K Murakami-Murofushi, ... Cellular signalling 22 (10), 1543-1553, 2010 | 64 | 2010 |
Identification of CXCL11 as a STAT3-dependent gene induced by IFN CH Yang, L Wei, SR Pfeffer, Z Du, A Murti, WJ Valentine, Y Zheng, ... The Journal of Immunology 178 (2), 986-992, 2007 | 61 | 2007 |
Interferonα Activates NF-κB in JAK1-deficient Cells through aTYK2-dependentPathway CH Yang, A Murti, WJ Valentine, Z Du, LM Pfeffer Journal of Biological Chemistry 280 (27), 25849-25853, 2005 | 58 | 2005 |
Chiral vinylphosphonate and phosphonate analogues of the immunosuppressive agent FTY720 X Lu, C Sun, WJ Valentine, S E, J Liu, G Tigyi, R Bittman The Journal of organic chemistry 74 (8), 3192-3195, 2009 | 55 | 2009 |
Subtype-specific residues involved in ligand activation of the endothelial differentiation gene family lysophosphatidic acid receptors WJ Valentine, JI Fells, DH Perygin, S Mujahid, K Yokoyama, Y Fujiwara, ... Journal of Biological Chemistry 283 (18), 12175-12187, 2008 | 50 | 2008 |
Protean agonism of the lysophosphatidic acid receptor‐1 with Ki16425 reduces nerve growth factor‐induced neurite outgrowth in pheochromocytoma 12 cells NA Moughal, CM Waters, WJ Valentine, M Connell, JC Richardson, ... Journal of neurochemistry 98 (6), 1920-1929, 2006 | 40 | 2006 |
Mitigation of radiation injury by selective stimulation of the LPA2 receptor GN Kiss, SC Lee, JI Fells, J Liu, WJ Valentine, Y Fujiwara, KE Thompson, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2013 | 38 | 2013 |
Lysophospholipid signaling: beyond the EDGs WJ Valentine, Y Fujiwara, R Tsukahara, G Tigyi Biochimica et Biophysica Acta (BBA)-General Subjects 1780 (3), 597-605, 2008 | 30 | 2008 |
Druggable lysophospholipid signaling pathways K Yanagida, WJ Valentine Druggable Lipid Signaling Pathways, 137-176, 2020 | 26 | 2020 |
Biosynthetic enzymes of membrane glycerophospholipid diversity as therapeutic targets for drug development WJ Valentine, T Hashidate–Yoshida, S Yamamoto, H Shindou Druggable Lipid Signaling Pathways, 5-27, 2020 | 26 | 2020 |
FTY720 (Gilenya) phosphate selectivity of sphingosine 1-phosphate receptor subtype 1 (S1P1) G protein-coupled receptor requires motifs in intracellular loop 1 and transmembrane … WJ Valentine, VI Godwin, DA Osborne, J Liu, Y Fujiwara, J Van Brocklyn, ... Journal of Biological Chemistry 286 (35), 30513-30525, 2011 | 24 | 2011 |
E, S.; Liu, J.; Tigyi, G.; Bittman, R X Lu, C Sun, WJ Valentine J. Org. Chem 74, 3192, 2009 | 16 | 2009 |
LPAAT3 incorporates docosahexaenoic acid into skeletal muscle cell membranes and is upregulated by PPARδ activation WJ Valentine, SM Tokuoka, D Hishikawa, Y Kita, H Shindou, T Shimizu Journal of Lipid Research 59 (2), 184-194, 2018 | 12 | 2018 |
High-Throughput Assays to Measure Intracellular Ca2+ Mobilization in Cells that Express Recombinant S1P Receptor Subtypes WJ Valentine, G Tigyi Sphingosine-1-Phosphate: Methods and Protocols, 77-87, 2012 | 10 | 2012 |
Lipidomic Analyses Reveal Specific Alterations of Phosphatidylcholine in Dystrophic Mdx Muscle WJ Valentine, SA Mostafa, SM Tokuoka, F Hamano, NF Inagaki, ... Frontiers in physiology 12, 698166, 2022 | 5 | 2022 |