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Alexander J. Bryer
Alexander J. Bryer
Department of Chemistry and Biochemistry, University of Delaware
Verified email at udel.edu
Title
Cited by
Cited by
Year
Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR
M Lu, RW Russell, AJ Bryer, CM Quinn, G Hou, H Zhang, CD Schwieters, ...
Nature structural & molecular biology 27 (9), 863-869, 2020
632020
Recognition of the TDP-43 nuclear localization signal by importin α1/β
SG Doll, H Meshkin, AJ Bryer, F Li, YH Ko, RK Lokareddy, RE Gillilan, ...
Cell reports 39 (13), 2022
382022
Structural basis for the homotypic fusion of chlamydial inclusions by the SNARE-like protein IncA
G Cingolani, M McCauley, A Lobley, AJ Bryer, J Wesolowski, DL Greco, ...
Nature communications 10 (1), 2747, 2019
312019
Molecular dynamics of the viral life cycle: progress and prospects
PE Jones, C Pérez-Segura, AJ Bryer, JR Perilla, JA Hadden-Perilla
Current opinion in virology 50, 128-138, 2021
292021
Full scale structural, mechanical and dynamical properties of HIV-1 liposomes
AJ Bryer, T Reddy, E Lyman, JR Perilla
PLOS Computational Biology 18 (1), e1009781, 2022
152022
Deep-learning in situ classification of HIV-1 virion morphology
JS Rey, W Li, AJ Bryer, H Beatson, C Lantz, AN Engelman, JR Perilla
Computational and structural biotechnology journal 19, 5688-5700, 2021
122021
Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization
AT Gres, KA Kirby, WM McFadden, H Du, D Liu, C Xu, AJ Bryer, JR Perilla, ...
Nature Communications 14 (1), 5614, 2023
102023
Performance efficient macromolecular mechanics via sub-nanometer shape based coarse graining
AJ Bryer, JS Rey, JR Perilla
Nature Communications 14 (1), 2014, 2023
102023
High-performance analysis of biomolecular containers to measure small-molecule transport, transbilayer lipid diffusion, and protein cavities
AJ Bryer, JA Hadden-Perilla, JE Stone, JR Perilla
Journal of chemical information and modeling 59 (10), 4328-4338, 2019
102019
Curvature of the retroviral capsid assembly is modulated by a molecular switch
T Thames, AJ Bryer, X Qiao, J Jeon, R Weed, K Janicki, B Hu, PL Gor’kov, ...
The journal of physical chemistry letters 12 (32), 7768-7776, 2021
92021
Elasticity of the HIV-1 core facilitates nuclear entry and infection
A Deshpande, AJ Bryer, JR Andino-Moncada, J Shi, J Hong, C Torres, ...
PLoS Pathogens 20 (9), e1012537, 2024
62024
Accelerating prediction of chemical shift of protein structures on GPUs: Using OpenACC
E Wright, MH Ferrato, AJ Bryer, R Searles, JR Perilla, S Chandrasekaran
PLoS computational biology 16 (5), e1007877, 2020
42020
GPU accelerated computation of isotropic chemical shifts offers new dimension of structure refinement in largescale molecular dynamics simulation
AJ Bryer, EF Wright, M Ferrato, T Huber, E Ortiz, R Searles, ...
Biophysical Journal 116 (3), 569a-570a, 2019
12019
Probing the Mechanoelastic Mysteries of the HIV-1 Capsid: A Journey Through Theoretical and Computational Biophysics
AJ Bryer
University of Delaware, 2024
2024
Unsupervised Refinement of Protein Structures
AJ Bryer, JS Rey, C Xu, JA Hadden-Perilla, JR Perilla
2023
Microtiter binding assays and in silico kinetic mapping reveal binding of TDP-43 nuclear localization signal to importin α is modulated by phosphorylation
H Meshkin, AJ Bryer, SG Doll, G Cingolani, JR Perilla
Biophysical Journal 121 (3), 41a, 2022
2022
Large scale all-atom molecular dynamics simulations of mutant CA tubes provide insights on cytotoxic T-lymphocyte-mediated HIV-1 restriction
AJ Bryer, M Balasubramaniam, S Thapa, BO Davids, C Xu, J Shi, C Aiken, ...
Biophysical Journal 121 (3), 321a, 2022
2022
Deep-learning in-situ classification of HIV-1 virion morphology
JS Rey, W Li, AJ Bryer, H Beatson, C Lantz, A Engelman, JR Perilla
Biophysical Journal 121 (3), 129a-130a, 2022
2022
MD Simulations of Full-Scale HIV-1 Lipid Envelope on LANL Grizzly Supercomputer [Slide]
A Bryer, TJE Reddy, E Lyman, JR Perilla
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States), 2021
2021
The Pentamer vs Hexamer Assembly of Retroviral Capsid Protein is Controlled by the Flexible Linker
B Chen, X Qiao, T Thames, AJ Bryer, J Jeon, I Hung, P Gorkov, Z Gan, ...
Biophysical Journal 120 (3), 24a, 2021
2021
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