Brain somatic mutations in MTOR reveal translational dysregulations underlying intractable focal epilepsy JK Kim, J Cho, SH Kim, HC Kang, DS Kim, VN Kim, JH Lee The Journal of clinical investigation 129 (10), 4207-4223, 2024 | 58 | 2024 |
Mechanistic target of rapamycin pathway in epileptic disorders JK Kim, JH Lee Journal of Korean Neurosurgical Society 62 (3), 272-287, 2019 | 40 | 2019 |
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank EG Overbey, JK Kim, BT Tierney, J Park, N Houerbi, AG Lucaci, ... Nature 632 (8027), 1145-1154, 2024 | 24 | 2024 |
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight JK Kim, BT Tierney, EG Overbey, E Dantas, M Fuentealba, J Park, ... Nature Communications 15 (1), 4954, 2024 | 23 | 2024 |
Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA) EG Overbey, K Ryon, JK Kim, BT Tierney, R Klotz, V Ortiz, S Mullane, ... Nature Communications 15 (1), 4964, 2024 | 21 | 2024 |
A second space age spanning omics, platforms and medicine across orbits CE Mason, J Green, KI Adamopoulos, EE Afshin, JJ Baechle, M Basner, ... Nature 632 (8027), 995-1008, 2024 | 16 | 2024 |
Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight BT Tierney, JK Kim, EG Overbey, KA Ryon, J Foox, MA Sierra, ... Nature Microbiology, 1-15, 2024 | 15 | 2024 |
Molecular and physiological changes in the SpaceX Inspiration4 civilian crew CW Jones, EG Overbey, J Lacombe, AJ Ecker, C Meydan, K Ryon, ... Nature 632 (8027), 1155-1164, 2024 | 13 | 2024 |
Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight F Wu, H Du, E Overbey, JK Kim, P Makhijani, N Martin, CA Lerner, ... Nature Communications 15 (1), 4795, 2024 | 11 | 2024 |
Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction K Siew, KA Nestler, C Nelson, V D’Ambrosio, C Zhong, Z Li, A Grillo, ... Nature Communications 15 (1), 4923, 2024 | 10 | 2024 |
Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight J Park, EG Overbey, SA Narayanan, JK Kim, BT Tierney, N Damle, ... Nature Communications 15 (1), 4773, 2024 | 10 | 2024 |
Spaceflight induces changes in gene expression profiles linked to insulin and estrogen BA Mathyk, M Tabetah, R Karim, V Zaksas, JK Kim, RI Anu, M Muratani, ... Communications Biology 7 (1), 692, 2024 | 9 | 2024 |
Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight JS Garcia-Medina, K Sienkiewicz, SA Narayanan, EG Overbey, ... Precision Clinical Medicine 7 (1), pbae007, 2024 | 8 | 2024 |
Spaceflight alters insulin and estrogen signaling pathways BA Mathyk, M Tabetah, R Karim, V Zaksas, JK Kim, I Anu, M Muratani, ... | 8 | 2023 |
Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight N Houerbi, JK Kim, EG Overbey, R Batra, A Schweickart, L Patras, ... Nature Communications 15 (1), 4862, 2024 | 7 | 2024 |
Secretome profiling captures acute changes in oxidative stress, brain homeostasis and coagulation from spaceflight N Houerbi, J Kim, EG Overbey Nat. Commun 10, 2024 | 7 | 2024 |
Design, synthesis and biological evaluation of novel MDH inhibitors targeting tumor microenvironment S Godesi, JR Han, JK Kim, DI Kwak, J Lee, H Nada, M Kim, HA Yang, ... Pharmaceuticals 16 (5), 683, 2023 | 7 | 2023 |
Protective alleles and precision healthcare in crewed spaceflight LA Rutter, MJ MacKay, H Cope, NJ Szewczyk, JK Kim, E Overbey, ... Nature Communications 15 (1), 6158, 2024 | 6 | 2024 |
The Space Omics and Medical Atlas (SOMA): A comprehensive data resource and biobank for astronauts EG Overbey, K Ryon, J Kim Nature, 2024 | 6 | 2024 |
Ethical considerations for the age of non-governmental space exploration A Seylani, AS Galsinh, A Tasoula, AR I, A Camera, J Calleja-Agius, J Borg, ... Nature Communications 15 (1), 4774, 2024 | 5 | 2024 |