| Folding and misfolding of human membrane proteins in health and disease: from single molecules to cellular proteostasis JT Marinko, H Huang, WD Penn, JA Capra, JP Schlebach, CR Sanders Chemical reviews 119 (9), 5537-5606, 2019 | 240 | 2019 |
| Pharmacological therapeutics targeting RNA-dependent RNA polymerase, proteinase and spike protein: from mechanistic studies to clinical trials for COVID-19 J Huang, W Song, H Huang, Q Sun Journal of clinical medicine 9 (4), 1131, 2020 | 188 | 2020 |
| Mechanisms of KCNQ1 channel dysfunction in long QT syndrome involving voltage sensor domain mutations H Huang, G Kuenze, JA Smith, KC Taylor, AM Duran, A Hadziselimovic, ... Science advances 4 (3), eaar2631, 2018 | 85 | 2018 |
| Constitutive activity of neural melanocortin receptors YX Tao, H Huang, ZQ Wang, F Yang, JN Williams, GV Nikiforovich Methods in enzymology 484, 267-279, 2010 | 79 | 2010 |
| Nitrite therapy improves left ventricular function during heart failure via restoration of nitric oxide–mediated cytoprotective signaling S Bhushan, K Kondo, DJ Polhemus, H Otsuka, CK Nicholson, YX Tao, ... Circulation research 114 (8), 1281-1291, 2014 | 77 | 2014 |
| Methods for measuring myeloperoxidase activity toward assessing inhibitor efficacy in living systems J Huang, A Milton, RD Arnold, H Huang, F Smith, JR Panizzi, P Panizzi Journal of Leucocyte Biology 99 (4), 541-548, 2016 | 66 | 2016 |
| Selective β2-Adrenoreceptor Stimulation Attenuates Myocardial Cell Death and Preserves Cardiac Function After Ischemia–Reperfusion Injury S Bhushan, K Kondo, BL Predmore, M Zlatopolsky, AL King, C Pearce, ... Arteriosclerosis, thrombosis, and vascular biology 32 (8), 1865-1874, 2012 | 55 | 2012 |
| Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state KC Taylor, PW Kang, P Hou, ND Yang, G Kuenze, JA Smith, J Shi, ... Elife 9, e53901, 2020 | 48 | 2020 |
| Predicting the functional impact of KCNQ1 variants of unknown significance B Li, JL Mendenhall, BM Kroncke, KC Taylor, H Huang, DK Smith, ... Circulation: Cardiovascular Genetics 10 (5), e001754, 2017 | 42 | 2017 |
| Pleiotropic functions of the transmembrane domain 6 of human melanocortin-4 receptor H Huang, YX Tao Journal of molecular endocrinology 49 (3), 237-248, 2012 | 42 | 2012 |
| Biased signaling in naturally occurring mutations in human melanocortin-3 receptor gene F Yang, H Huang, YX Tao International journal of biological sciences 11 (4), 423, 2015 | 39 | 2015 |
| Functions of the DRY motif and intracellular loop 2 of human melanocortin 3 receptor H Huang, YX Tao J Mol Endocrinol 53 (3), 319-330, 2014 | 37 | 2014 |
| Ipsen 5i is a novel potent pharmacoperone for intracellularly retained melanocortin-4 receptor mutants YX Tao, H Huang Frontiers in endocrinology 5, 2014 | 36 | 2014 |
| Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: a new paradigm for drug discovery J Huang, D Wang, LH Huang, H Huang International journal of molecular sciences 21 (3), 739, 2020 | 34 | 2020 |
| Pharmacological chaperones for the misfolded melanocortin-4 receptor associated with human obesity H Huang, W Wang, YX Tao Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (10 …, 2017 | 33 | 2017 |
| A small molecule agonist THIQ as a novel pharmacoperone for intracellularly retained melanocortin-4 receptor mutants H Huang, YX Tao International journal of biological sciences 10 (8), 817, 2014 | 33 | 2014 |
| Reciprocal modulation between amyloid precursor protein and synaptic membrane cholesterol revealed by live cell imaging CE DelBove, CE Strothman, RM Lazarenko, H Huang, CR Sanders, ... Neurobiology of disease 127, 449-461, 2019 | 26 | 2019 |
| Brain-derived neurotrophic factor in human subjects with function-altering melanocortin-4 receptor variants MG Hohenadel, MS Thearle, BA Grice, H Huang, MH Dai, YX Tao, ... International journal of obesity 38 (8), 1068-1074, 2014 | 25 | 2014 |
| Physiology and therapeutics of the free fatty acid receptor GPR40 H Huang, MH Dai, YX Tao Progress in molecular biology and translational science 121, 67-94, 2014 | 22 | 2014 |
| Collision-induced unfolding differentiates functional variants of the KCNQ1 voltage sensor domain SM Fantin, H Huang, CR Sanders, BT Ruotolo Journal of the American Society for Mass Spectrometry 31 (11), 2348-2355, 2020 | 19 | 2020 |