| Translational control by MAPK signaling in long-term synaptic plasticity and memory RJ Kelleher, A Govindarajan, HY Jung, H Kang, S Tonegawa Cell 116 (3), 467-479, 2004 | 1002 | 2004 |
| Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration CA Saura, SY Choi, V Beglopoulos, S Malkani, D Zhang, BSS Rao, ... Neuron 42 (1), 23-36, 2004 | 915 | 2004 |
| Translational regulatory mechanisms in persistent forms of synaptic plasticity RJ Kelleher, A Govindarajan, S Tonegawa Neuron 44 (1), 59-73, 2004 | 749 | 2004 |
| The autistic neuron: troubled translation? RJ Kelleher, MF Bear Cell 135 (3), 401-406, 2008 | 724 | 2008 |
| The presenilin hypothesis of Alzheimer's disease: evidence for a loss-of-function pathogenic mechanism J Shen, RJ Kelleher III Proceedings of the National Academy of Sciences 104 (2), 403-409, 2007 | 638 | 2007 |
| A novel mediator between activator proteins and the RNA polymerase II transcription apparatus RJ Kelleher III, PM Flanagan, RD Kornberg Cell 61 (7), 1209-1215, 1990 | 629 | 1990 |
| A mediator required for activation of RNA polymerase II transcription in vitro PM Flanagan, RJ Kelleher III, MH Sayre, H Tschochner, RD Kornberg Nature 350 (6317), 436-438, 1991 | 590* | 1991 |
| Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice Y Tong, H Yamaguchi, E Giaime, S Boyle, R Kopan, RJ Kelleher III, ... Proceedings of the National Academy of Sciences 107 (21), 9879-9884, 2010 | 585 | 2010 |
| A clustered plasticity model of long-term memory engrams A Govindarajan, RJ Kelleher, S Tonegawa Nature Reviews Neuroscience 7 (7), 575-583, 2006 | 415 | 2006 |
| Presenilin-1 mutations and Alzheimer’s disease RJ Kelleher III, J Shen Proceedings of the National Academy of Sciences 114 (4), 629-631, 2017 | 298 | 2017 |
| Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer’s disease D Xia, H Watanabe, B Wu, SH Lee, Y Li, E Tsvetkov, VY Bolshakov, ... Neuron 85 (5), 967-981, 2015 | 274 | 2015 |
| Tsx Produces a Long Noncoding RNA and Has General Functions in the Germline, Stem Cells, and Brain MC Anguera, W Ma, D Clift, S Namekawa, RJ Kelleher III, JT Lee PLoS genetics 7 (9), e1002248, 2011 | 198 | 2011 |
| Effects of activation-defective TBP mutations on transcription initiation in yeast TK Kim, S Hashimoto, RJ Kelleher III, PM Flanagan, RD Kornberg, ... Nature 369 (6477), 252-255, 1994 | 142 | 1994 |
| High-throughput sequencing of mGluR signaling pathway genes reveals enrichment of rare variants in autism RJ Kelleher III, U Geigenmüller, H Hovhannisyan, E Trautman, R Pinard, ... PloS one 7 (4), e35003, 2012 | 136 | 2012 |
| A mixed modality approach towards Xi reactivation for Rett syndrome and other X-linked disorders LLG Carrette, CY Wang, C Wei, W Press, W Ma, RJ Kelleher III, JT Lee Proceedings of the National Academy of Sciences 115 (4), E668-E675, 2018 | 107 | 2018 |
| Sequence-dependent energetics of the BZ transition in supercoiled DNA containing nonalternating purine-pyrimidine sequences. MJ Ellison, RJ Kelleher 3rd, AH Wang, JF Habener, A Rich Proceedings of the National Academy of Sciences 82 (24), 8320-8324, 1985 | 107 | 1985 |
| Extracellular vesicles present in human ovarian tumor microenvironments induce a phosphatidylserine-dependent arrest in the T-cell signaling cascade RJ Kelleher Jr, S Balu-Iyer, J Loyall, AJ Sacca, GN Shenoy, P Peng, V Iyer, ... Cancer immunology research 3 (11), 1269-1278, 2015 | 104 | 2015 |
| A presenilin-1 mutation identified in familial Alzheimer disease with cotton wool plaques causes a nearly complete loss of γ-secretase activity EA Heilig, W Xia, J Shen, RJ Kelleher Journal of Biological Chemistry 285 (29), 22350-22359, 2010 | 103 | 2010 |
| Characterization of Age-Dependent and Progressive Cortical Neuronal Degeneration in Presenilin Conditional Mutant Mice M Wines-Samuelson, EC Schulte, MJ Smith, C Aoki, X Liu, RJ Kelleher III, ... PLoS One 5 (4), e10195, 2010 | 101 | 2010 |
| Sialic acid–dependent inhibition of t cells by exosomal ganglioside GD3 in ovarian tumor microenvironments GN Shenoy, J Loyall, CS Berenson, RJ Kelleher, V Iyer, SV Balu-Iyer, ... The Journal of Immunology 201 (12), 3750-3758, 2018 | 97 | 2018 |
