| The repertoire of mutational signatures in human cancer LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AW Tian Ng, Y Wu, ... Nature 578 (7793), 94-101, 2020 | 3066 | 2020 |
| Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 2031* | 2020 |
| Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma A Jusakul, I Cutcutache, CH Yong, JQ Lim, MN Huang, N Padmanabhan, ... Cancer discovery 7 (10), 1116-1135, 2017 | 837 | 2017 |
| Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia AWT Ng, SL Poon, MN Huang, JQ Lim, A Boot, W Yu, Y Suzuki, ... Science translational medicine 9 (412), eaan6446, 2017 | 367 | 2017 |
| Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study E Domingo, L Freeman-Mills, E Rayner, M Glaire, S Briggs, L Vermeulen, ... The lancet Gastroenterology & hepatology 1 (3), 207-216, 2016 | 323 | 2016 |
| Genomic and transcriptomic profiling of combined hepatocellular and intrahepatic cholangiocarcinoma reveals distinct molecular subtypes R Xue, LU Chen, C Zhang, M Fujita, R Li, SM Yan, CK Ong, X Liao, Q Gao, ... Cancer cell 35 (6), 932-947. e8, 2019 | 235 | 2019 |
| In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors A Boot, MN Huang, AWT Ng, SC Ho, JQ Lim, Y Kawakami, K Chayama, ... Genome research 28 (5), 654-665, 2018 | 160 | 2018 |
| Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors MN Huang, W Yu, WW Teoh, M Ardin, A Jusakul, AWT Ng, A Boot, ... Genome research 27 (9), 1475-1486, 2017 | 121 | 2017 |
| Associations of polymorphisms of eight muscle-or metabolism-related genes with performance in Mount Olympus marathon runners GI Tsianos, E Evangelou, A Boot, M Carola Zillikens, JBJ van Meurs, ... Journal of applied physiology 108 (3), 567-574, 2010 | 107 | 2010 |
| Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma JY Chan, JQ Lim, J Yeong, V Ravi, P Guan, A Boot, TKY Tay, ... The Journal of clinical investigation 130 (11), 5833-5846, 2020 | 86 | 2020 |
| Characterization of colibactin-associated mutational signature in an Asian oral squamous cell carcinoma and in other mucosal tumor types A Boot, AWT Ng, FT Chong, SC Ho, W Yu, DSW Tan, NG Iyer, SG Rozen Genome Research 30 (6), 803-813, 2020 | 58* | 2020 |
| The mutational landscape of early‐and typical‐onset oral tongue squamous cell carcinoma BR Campbell, Z Chen, DL Faden, N Agrawal, RJ Li, GJ Hanna, NG Iyer, ... Cancer 127 (4), 544-553, 2021 | 48 | 2021 |
| Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples MH Bailey, WU Meyerson, LJ Dursi, LB Wang, G Dong, WW Liang, ... Nature communications 11 (1), 4748, 2020 | 46 | 2020 |
| Tumor LINE-1 methylation level in association with survival of patients with stage II colon cancer M Swets, A Zaalberg, A Boot, T Van Wezel, MA Frouws, E Bastiaannet, ... International journal of molecular sciences 18 (1), 36, 2016 | 42 | 2016 |
| A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation D Ray, YC Yun, M Idris, S Cheng, A Boot, TBH Iain, SG Rozen, P Tan, ... Proceedings of the National Academy of Sciences 117 (28), 16391-16400, 2020 | 41 | 2020 |
| Imprinted survival genes preclude loss of heterozygosity of chromosome 7 in cancer cells A Boot, J Oosting, NFCC de Miranda, Y Zhang, WE Corver, ... The Journal of pathology 240 (1), 72-83, 2016 | 39 | 2016 |
| BRAF mutation-specific promoter methylation of FOX genes in colorectal cancer EH van Roon, A Boot, AA Dihal, RF Ernst, T van Wezel, H Morreau, ... Clinical epigenetics 5, 1-10, 2013 | 38 | 2013 |
| Mutational processes in hepatocellular carcinoma: the story of aristolochic acid JC Nault, E Letouzé Seminars in liver disease 39 (03), 334-340, 2019 | 35 | 2019 |
| Recurrent coding sequence variation explains only a small fraction of the genetic architecture of colorectal cancer MN Timofeeva, B Kinnersley, SM Farrington, N Whiffin, C Palles, V Svinti, ... Scientific reports 5 (1), 16286, 2015 | 33 | 2015 |
| Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers A Boot, M Liu, N Stantial, V Shah, W Yu, KC Nitiss, JL Nitiss, ... Proceedings of the National Academy of Sciences 119 (4), e2114024119, 2022 | 32 | 2022 |
Steven G. RozenDuke University School of MedicineVerified email at duke.edu