| Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating … P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ... Archives of toxicology 87, 1315-1530, 2013 | 1463 | 2013 |
| Inflammation, immunoregulation, and inducible nitric oxide synthase AK Nussler, TR Billiar Journal of leukocyte biology 54 (2), 171-178, 1993 | 1243 | 1993 |
| Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes. DA Geller, CJ Lowenstein, RA Shapiro, AK Nussler, M Di Silvio, SC Wang, ... Proceedings of the National Academy of Sciences 90 (8), 3491-3495, 1993 | 1105 | 1993 |
| Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes. DA Geller, AK Nussler, M Di Silvio, CJ Lowenstein, RA Shapiro, SC Wang, ... Proceedings of the National Academy of Sciences 90 (2), 522-526, 1993 | 874 | 1993 |
| The genetic determinants of the CYP3A5 polymorphism E Hustert, M Haberl, O Burk, R Wolbold, YQ He, K Klein, AC Nuessler, ... Pharmacogenetics and Genomics 11 (9), 773-779, 2001 | 858 | 2001 |
| Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver T Lang, K Klein, J Fischer, AK Nüssler, P Neuhaus, U Hofmann, ... Pharmacogenetics and Genomics 11 (5), 399-415, 2001 | 715 | 2001 |
| Sex is a major determinant of CYP3A4 expression in human liver R Wolbold, K Klein, O Burk, AK Nüssler, P Neuhaus, M Eichelbaum, ... Hepatology 38 (4), 978-988, 2003 | 622 | 2003 |
| Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene. NA Chartrain, DA Geller, PP Koty, NF Sitrin, AK Nussler, EP Hoffman, ... Journal of biological chemistry 269 (9), 6765-6772, 1994 | 573 | 1994 |
| Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin. AK Nussler, M Di Silvio, TR Billiar, RA Hoffman, DA Geller, R Selby, ... The Journal of experimental medicine 176 (1), 261-264, 1992 | 531 | 1992 |
| Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: initial analysis of the human NOS2 promoter. ME De Vera, RA Shapiro, AK Nussler, JS Mudgett, RL Simmons, ... Proceedings of the National Academy of Sciences 93 (3), 1054-1059, 1996 | 477 | 1996 |
| Improved Methods to Measure End Products of Nitric Oxide in Biological Fluids: Nitrite, Nitrate, andS-Nitrosothiols M Marzinzig, AK Nussler, J Stadler, E Marzinzig, W Barthlen, NC Nussler, ... Nitric oxide 1 (2), 177-189, 1997 | 440 | 1997 |
| Interindividual variability and tissue-specificity in the expression of cytochrome P450 3A mRNA I Koch, R Weil, R Wolbold, J Brockmöller, E Hustert, O Burk, A Nuessler, ... Drug Metabolism and Disposition 30 (10), 1108-1114, 2002 | 420 | 2002 |
| Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways P Yao, A Nussler, L Liu, L Hao, F Song, A Schirmeier, N Nussler Journal of hepatology 47 (2), 253-261, 2007 | 416 | 2007 |
| Glutathione depletion causes cell growth inhibition and enhanced apoptosis in pancreatic cancer cells T Schnelldorfer, S Gansauge, F Gansauge, S Schlosser, HG Beger, ... Cancer: Interdisciplinary International Journal of the American Cancer …, 2000 | 299 | 2000 |
| Oxidative stress-mediated cytotoxicity and metabolism of T-2 toxin and deoxynivalenol in animals and humans: an update QH Wu, X Wang, W Yang, AK Nüssler, LY Xiong, K Kuča, V Dohnal, ... Archives of toxicology 88, 1309-1326, 2014 | 293 | 2014 |
| Characterization of Plasmodium falciparum sporozoite surface protein 2. WO Rogers, A Malik, S Mellouk, K Nakamura, MD Rogers, A Szarfman, ... Proceedings of the National Academy of Sciences 89 (19), 9176-9180, 1992 | 286 | 1992 |
| Present status and perspectives of cell-based therapies for liver diseases A Nussler, S Konig, M Ott, E Sokal, B Christ, W Thasler, M Brulport, ... Journal of hepatology 45 (1), 144-159, 2006 | 281 | 2006 |
| Coinduction of nitric oxide synthase and argininosuccinate synthetase in a murine macrophage cell line. Implications for regulation of nitric oxide production. AK Nussler, TR Billiar, ZZ Liu, SM Morris Jr Journal of Biological Chemistry 269 (2), 1257-1261, 1994 | 280 | 1994 |
| Interindividual variability of canalicular ATP‐binding‐cassette (ABC)–transporter expression in human liver Y Meier, C Pauli‐Magnus, UM Zanger, K Klein, E Schaeffeler, AK Nussler, ... Hepatology 44 (1), 62-74, 2006 | 278 | 2006 |
| Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor O Burk, KA Arnold, AK Nussler, E Schaeffeler, E Efimova, BA Avery, ... Molecular pharmacology 67 (6), 1954-1965, 2005 | 271 | 2005 |
Timothy BilliarUniversity of PittsburghVerified email at upmc.edu
