| EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells CG Kleer, Q Cao, S Varambally, R Shen, I Ota, SA Tomlins, D Ghosh, ... Proceedings of the national academy of sciences 100 (20), 11606-11611, 2003 | 2039 | 2003 |
| A Wnt–Axin2–GSK3β cascade regulates Snail1 activity in breast cancer cells JI Yook, XY Li, I Ota, C Hu, HS Kim, NH Kim, SY Cha, JK Ryu, YJ Choi, ... Nature cell biology 8 (12), 1398-1406, 2006 | 753 | 2006 |
| Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP F Sabeh, I Ota, K Holmbeck, H Birkedal-Hansen, P Soloway, M Balbin, ... The Journal of cell biology 167 (4), 769-781, 2004 | 700 | 2004 |
| Wnt-dependent regulation of the E-cadherin repressor snail JI Yook, XY Li, I Ota, ER Fearon, SJ Weiss Journal of biological chemistry 280 (12), 11740-11748, 2005 | 561 | 2005 |
| MT1-MMP–dependent neovessel formation within the confines of the three-dimensional extracellular matrix TH Chun, F Sabeh, I Ota, H Murphy, KT McDonagh, K Holmbeck, ... The Journal of cell biology 167 (4), 757-767, 2004 | 433 | 2004 |
| Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion Y Zhai, R Kuick, B Nan, I Ota, SJ Weiss, CL Trimble, ER Fearon, KR Cho Cancer research 67 (21), 10163-10172, 2007 | 300 | 2007 |
| Induction of a MT1-MMP and MT2-MMP-dependent basement membrane transmigration program in cancer cells by Snail1 I Ota, XY Li, Y Hu, SJ Weiss Proceedings of the National Academy of Sciences 106 (48), 20318-20323, 2009 | 278 | 2009 |
| Snail1 is stabilized by O‐GlcNAc modification in hyperglycaemic condition SY Park, HS Kim, NH Kim, S Ji, SY Cha, JG Kang, I Ota, K Shimada, ... The EMBO journal 29 (22), 3787-3796, 2010 | 203 | 2010 |
| MT1-matrix metalloproteinase directs arterial wall invasion and neointima formation by vascular smooth muscle cells S Filippov, GC Koenig, TH Chun, KB Hotary, I Ota, TH Bugge, JD Roberts, ... The Journal of experimental medicine 202 (5), 663-671, 2005 | 151 | 2005 |
| Molecular dissection of the structural machinery underlying the tissue-invasive activity of membrane type-1 matrix metalloproteinase XY Li, I Ota, I Yana, F Sabeh, SJ Weiss Molecular biology of the cell 19 (8), 3221-3233, 2008 | 150 | 2008 |
| Weekly cisplatin plus radiation for postoperative head and neck cancer (JCOG1008): a multicenter, noninferiority, phase II/III randomized controlled trial N Kiyota, M Tahara, J Mizusawa, T Kodaira, H Fujii, T Yamazaki, H Mitani, ... Journal of Clinical Oncology 40 (18), 1980-1990, 2022 | 145 | 2022 |
| Increased expression of integrin α3β1 in highly brain metastatic subclone of a human non‐small cell lung cancer cell line T Yoshimasu, T Sakurai, S Oura, I Hirai, H Tanino, Y Kokawa, Y Naito, ... Cancer science 95 (2), 142-148, 2004 | 121 | 2004 |
| Snail-induced EMT promotes cancer stem cell-like properties in head and neck cancer cells I Ota, T Masui, M Kurihara, JI Yook, S Mikami, T Kimura, K Shimada, ... Oncology reports 35 (1), 261-266, 2016 | 106 | 2016 |
| Helicobacter pylori CagA promotes Snail-mediated epithelial–mesenchymal transition by reducing GSK-3 activity DG Lee, HS Kim, YS Lee, S Kim, SY Cha, I Ota, NH Kim, YH Cha, ... Nature communications 5 (1), 4423, 2014 | 105 | 2014 |
| Prevalence of human papillomavirus in oropharyngeal cancer: a multicenter study in Japan T Hama, Y Tokumaru, M Fujii, K Yane, K Okami, K Kato, M Masuda, ... Oncology 87 (3), 173-182, 2014 | 102 | 2014 |
| Snail-induced epithelial-mesenchymal transition promotes cancer stem cell-like phenotype in head and neck cancer cells T Masui, I Ota, JI Yook, S Mikami, K Yane, T Yamanaka, H Hosoi International journal of oncology 44 (3), 693-699, 2014 | 86 | 2014 |
| Transfection with mutant p53 gene inhibits heat-induced apoptosis in a head and neck cell line of human squamous cell carcinoma I Ota, K Ohnishi, A Takahashi, K Yane, H Kanata, H Miyahara, T Ohnishi, ... International Journal of Radiation Oncology* Biology* Physics 47 (2), 495-501, 2000 | 82 | 2000 |
| Function of JunB in transient amplifying cell senescence and progression of human prostate cancer N Konishi, K Shimada, M Nakamura, E Ishida, I Ota, N Tanaka, K Fujimoto Clinical Cancer Research 14 (14), 4408-4416, 2008 | 78 | 2008 |
| Effect of rapamycin, an mTOR inhibitor, on radiation sensitivity of lung cancer cells having different p53 gene status Y Nagata, A Takahashi, K Ohnishi, I Ota, T Ohnishi, T Tojo, S Taniguchi International journal of oncology 37 (4), 1001-1010, 2010 | 71 | 2010 |
| Transfection of mutant p53 gene depresses X-ray- or CDDP-induced apoptosis in a human squamous cell carcinoma of the head and neck K Ohnishi, I Ota, A Takahashi, K Yane, H Matsumoto, T Ohnishi Apoptosis 7, 367-372, 2002 | 56 | 2002 |
