| Small molecule targeted recruitment of a nuclease to RNA MG Costales, Y Matsumoto, SP Velagapudi, MD Disney Journal of the American Chemical Society 140 (22), 6741-6744, 2018 | 188 | 2018 |
| Small molecule inhibition of microRNA-210 reprograms an oncogenic hypoxic circuit MG Costales, CL Haga, SP Velagapudi, JL Childs-Disney, DG Phinney, ... Journal of the American Chemical Society 139 (9), 3446-3455, 2017 | 175 | 2017 |
| How we think about targeting RNA with small molecules MG Costales, JL Childs-Disney, HS Haniff, MD Disney Journal of medicinal chemistry 63 (17), 8880-8900, 2020 | 163 | 2020 |
| Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer MG Costales, H Aikawa, Y Li, JL Childs-Disney, D Abegg, DG Hoch, ... Proceedings of the National Academy of Sciences 117 (5), 2406-2411, 2020 | 153 | 2020 |
| Targeted degradation of a hypoxia-associated non-coding RNA enhances the selectivity of a small molecule interacting with RNA MG Costales, B Suresh, K Vishnu, MD Disney Cell Chemical Biology 26 (8), 1180-1186. e5, 2019 | 104 | 2019 |
| Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNA P Zhang, HJ Park, J Zhang, E Junn, RJ Andrews, SP Velagapudi, ... Proceedings of the National Academy of Sciences 117 (3), 1457-1467, 2020 | 99 | 2020 |
| Approved anti-cancer drugs target oncogenic non-coding RNAs SP Velagapudi, MG Costales, BR Vummidi, Y Nakai, AJ Angelbello, ... Cell Chemical Biology 25 (9), 1086-1094. e7, 2018 | 85 | 2018 |
| Programming inactive RNA-binding small molecules into bioactive degraders Y Tong, Y Lee, X Liu, JL Childs-Disney, BM Suresh, RI Benhamou, ... Nature 618 (7963), 169-179, 2023 | 69 | 2023 |
| A designed small molecule inhibitor of a non-coding RNA sensitizes HER2 negative cancers to herceptin MG Costales, DG Hoch, D Abegg, JL Childs-Disney, SP Velagapudi, ... Journal of the American Chemical Society 141 (7), 2960-2974, 2019 | 66 | 2019 |
| Extracellular adenosine generation in the regulation of pro-inflammatory responses and pathogen colonization MS Alam, MG Costales, C Cavanaugh, K Williams Biomolecules 5 (2), 775-792, 2015 | 53 | 2015 |
| A clipped [3] rotaxane derived from bis-nor-seco-cucurbit [10] uril JB Wittenberg, MG Costales, PY Zavalij, L Isaacs Chemical Communications 47 (33), 9420-9422, 2011 | 45 | 2011 |
| Ecto-5′-nucleotidase (CD73) regulates host inflammatory responses and exacerbates murine salmonellosis MS Alam, JL Kuo, PB Ernst, V Derr-Castillo, M Pereira, D Gaines, ... Scientific reports 4 (1), 4486, 2014 | 27 | 2014 |
| Extracellular adenosine produced by ecto-5′-nucleotidase (CD73) regulates macrophage pro-inflammatory responses, nitric oxide production, and favors Salmonella persistence MG Costales, MS Alam, C Cavanaugh, KM Williams Nitric Oxide 72, 7-15, 2018 | 23 | 2018 |
| Comparison of small molecules and oligonucleotides that target a toxic, non-coding RNA MG Costales, SG Rzuczek, MD Disney Bioorganic & medicinal chemistry letters 26 (11), 2605-2609, 2016 | 22 | 2016 |
| Gini coefficients as a single value metric to define chemical probe selectivity A Ursu, JL Childs-Disney, AJ Angelbello, MG Costales, SM Meyer, ... ACS chemical biology 15 (8), 2031-2040, 2020 | 20 | 2020 |
| Identifying and validating small molecules interacting with RNA (SMIRNAs) MD Disney, SP Velagapudi, Y Li, MG Costales, JL Childs-Disney Methods in enzymology 623, 45-66, 2019 | 13 | 2019 |
| Oral exposure to Listeria monocytogenes in aged IL-17RKO mice: A possible murine model to study listeriosis in susceptible populations MS Alam, M Costales, C Cavanaugh, M Pereira, D Gaines, K Williams Microbial pathogenesis 99, 236-246, 2016 | 12 | 2016 |
| Computational tools for design of selective small molecules targeting RNA: from small molecule microarrays to chemical similarity searching MG Costales, JL Childs-Disney, MD Disney RNA Therapeutics, 1-16, 2018 | 5 | 2018 |
| Down-regulation of CD73 expression favors host protection during Intracellular foodborne bacterial infections (IRC8P. 496) M Alam, M Costales, K Williams The Journal of Immunology 192 (1_Supplement), 190.24-190.24, 2014 | 3 | 2014 |
| Small-molecule Targeted Degradation of RNA A Ursu, MG Costales, JL Childs-Disney, MD Disney | 1 | 2020 |
