| De novo NAD+ synthesis enhances mitochondrial function and improves health E Katsyuba, A Mottis, M Zietak, F De Franco, V van der Velpen, K Gariani, ... Nature 563 (7731), 354-359, 2018 | 404 | 2018 |
| Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors M Ferri, P Liscio, A Carotti, S Asciutti, R Sardella, A Macchiarulo, ... European Journal of Medicinal Chemistry 142, 506-522, 2017 | 58 | 2017 |
| α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) inhibitors as novel modulators of de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis R Pellicciari, P Liscio, N Giacchè, F De Franco, A Carotti, J Robertson, ... Journal of medicinal chemistry 61 (3), 745-759, 2018 | 45 | 2018 |
| Design, Synthesis, Crystallographic Studies, and Preliminary Biological Appraisal of New Substituted Triazolo[4,3-b]pyridazin-8-amine Derivatives as Tankyrase … P Liscio, A Carotti, S Asciutti, T Karlberg, D Bellocchi, L Llacuna, ... Journal of medicinal chemistry 57 (6), 2807-2812, 2014 | 45 | 2014 |
| From polypharmacology to target specificity: the case of PARP inhibitors P Liscio, E Camaioni, A Carotti, R Pellicciari, A Macchiarulo Current Topics in Medicinal Chemistry 13 (23), 2939-2954, 2013 | 42 | 2013 |
| Concepts and Molecular Aspects in the Polypharmacology of PARP‐1 Inhibitors D Passeri, E Camaioni, P Liscio, P Sabbatini, M Ferri, A Carotti, ... ChemMedChem 11 (12), 1219-1226, 2016 | 36 | 2016 |
| Scaffold hopping approach on the route to selective tankyrase inhibitors P Liscio, A Carotti, S Asciutti, M Ferri, MM Pires, S Valloscuro, J Ziff, ... European journal of medicinal chemistry 87, 611-623, 2014 | 22 | 2014 |
| Discovery and characterization of novel potent PARP-1 inhibitors endowed with neuroprotective properties: From TIQ-A to HYDAMTIQ R Pellicciari, E Camaioni, AM Gilbert, A Macchiarulo, JA Bikker, F Shah, ... MedChemComm 2 (6), 559-565, 2011 | 22 | 2011 |
| Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy JR Marchand, A Carotti, D Passeri, P Filipponi, P Liscio, E Camaioni, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (10), 1765-1772, 2014 | 20 | 2014 |
| Fragment based drug design and diversity-oriented synthesis of carboxylic acid isosteres M Ferri, M Alunno, FA Greco, A Mammoli, G Saluti, A Carotti, R Sardella, ... Bioorganic & Medicinal Chemistry 28 (22), 115731, 2020 | 12 | 2020 |
| Structural basis of human dimeric α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase inhibition with TES-1025 M Cianci, N Giacchè, L Cialabrini, A Carotti, P Liscio, E Rosatelli, ... Frontiers in Molecular Biosciences 9, 834700, 2022 | 6 | 2022 |
| Therapeutic Potential of a Novel Poly (ADP-ribose) Polymerase Inhibitor, Hydamtiq, in Human Pancreatic and Colon Cancers S Asciutti, E Camaioni, P Mong, N Biran, A Carotti, P Liscio, G Akiri, ... Gastroenterology 144, 875-875, 2013 | 2 | 2013 |
| Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase R Pellicciari, P Liscio, N Giacche, F De Franco US Patent App. 17/325,068, 2021 | 1 | 2021 |
| HETEROARYL AND HETEROCYCLIC COMPOUNDS FOR TREATING ACUTE INFLAMMATION R Pellicciari, N Giacchè, F De Franco, P Liscio US Patent App. 18/673,091, 2024 | | 2024 |
| Discovery, properties and structural biology appraisals of TES-1025 as the first in class potent and selective ACMSD inhibitor P Liscio, E Rosatelli, M Cianci, A Carotti, N Giacchè, F De Franco, ... EFMC-ISMC Book of abstracts, 2024 | | 2024 |
| Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase R Pellicciari, P Liscio, N Giacche, F De Franco US Patent App. 18/447,130, 2023 | | 2023 |
| Design, Synthesis, Crystallographic Studies, and Biological Appraisals of New Tankyrase Inhibitors. E Camaioni, P Liscio, S Asciutti, A Carotti, A Macchiarulo, M Ferri, ... Atti del Congresso, 2014 | | 2014 |
| Novel Wnt-Targeted Therapy Inhibitors for Hepatocellular Carcinoma S Asciutti, E Ferretti, S Valloscuro, MM Pires, L Llacuna, D Esposito, ... Gastroenterology 146, 690-690, 2014 | | 2014 |
| Targeting the FXR Nuclear Receptor through a Virtual Screening Approach A Carotti, A Gioiello, A Macchiarulo, M Marinozzi, P Liscio, P Sabbatini, ... Atti del XXIV Congresso Nazionale della Società Chimica Italiana, FAR-PO-12, 2011 | | 2011 |
| Synthesis, enantiomeric separation and preliminary evaluation of a series of new thioidantoine derivatives as inhibitors of indoleamine-2, 3-dioxygenase (IDO), a novel target … P Liscio, E Camaioni, R Sardella, R Nuti, A Macchiarulo, G Pittelli, ... XXX Convegno Interregionale Tosco Umbro Marchigiano Abruzzese TUMA 2011, 2011 | | 2011 |
Andrea CarottiPerugia, BariVerified email at unipg.it