| Alternative cleavage and polyadenylation in health and disease AJ Gruber, M Zavolan Nature reviews Genetics 20 (10), 599-614, 2019 | 387 | 2019 |
| ISMARA: automated modeling of genomic signals as a democracy of regulatory motifs PJ Balwierz, M Pachkov, P Arnold, AJ Gruber, M Zavolan, ... Genome research 24 (5), 869-884, 2014 | 334 | 2014 |
| Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor SMA Islam, M Díaz-Gay, Y Wu, M Barnes, R Vangara, EN Bergstrom, ... Cell Genomics 2 (11), 2022 | 243 | 2022 |
| A comprehensive analysis of 3′ end sequencing data sets reveals novel polyadenylation signals and the repressive role of heterogeneous ribonucleoprotein C on cleavage and … AJ Gruber, R Schmidt, AR Gruber, G Martin, S Ghosh, M Belmadani, ... Genome research 26 (8), 1145-1159, 2016 | 219 | 2016 |
| PolyASite 2.0: a consolidated atlas of polyadenylation sites from 3′ end sequencing CJ Herrmann, R Schmidt, A Kanitz, P Artimo, AJ Gruber, M Zavolan Nucleic acids research 48 (D1), D174-D179, 2020 | 182 | 2020 |
| Global 3′ UTR shortening has a limited effect on protein abundance in proliferating T cells AR Gruber, G Martin, P Müller, A Schmidt, AJ Gruber, R Gumienny, ... Nature communications 5 (1), 5465, 2014 | 175 | 2014 |
| Comparative assessment of methods for the computational inference of transcript isoform abundance from RNA-seq data A Kanitz, F Gypas, AJ Gruber, AR Gruber, G Martin, M Zavolan Genome biology 16, 1-26, 2015 | 169 | 2015 |
| Differential transcriptional responses to Ebola and Marburg virus infection in bat and human cells M Hölzer, V Krähling, F Amman, E Barth, SH Bernhart, VAO Carmelo, ... Scientific reports 6 (1), 34589, 2016 | 70 | 2016 |
| Discovery of physiological and cancer-related regulators of 3′ UTR processing with KAPAC AJ Gruber, R Schmidt, S Ghosh, G Martin, AR Gruber, E van Nimwegen, ... Genome biology 19, 1-17, 2018 | 64 | 2018 |
| Pegylated IFN-α regulates hepatic gene expression through transient Jak/STAT activation MT Dill, Z Makowska, G Trincucci, AJ Gruber, JE Vogt, M Filipowicz, ... The Journal of clinical investigation 124 (4), 1568-1581, 2014 | 61 | 2014 |
| Signatures of TOP1 transcription-associated mutagenesis in cancer and germline MAM Reijns, DA Parry, TC Williams, F Nadeu, RL Hindshaw, ... Nature 602 (7898), 623-631, 2022 | 54 | 2022 |
| Modulation of epigenetic regulators and cell fate decisions by miRNAs AJ Gruber, M Zavolan Epigenomics 5 (6), 671-683, 2013 | 51 | 2013 |
| Embryonic stem cell-specific microRNAs contribute to pluripotency by inhibiting regulators of multiple differentiation pathways AJ Gruber, WA Grandy, PJ Balwierz, YA Dimitrova, M Pachkov, C Ciaudo, ... Nucleic acids research 42 (14), 9313-9326, 2014 | 49 | 2014 |
| Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis MG Ferrarini, A Lal, R Rebollo, AJ Gruber, A Guarracino, IM Gonzalez, ... Communications biology 4 (1), 590, 2021 | 43 | 2021 |
| Germline MBD4 deficiency causes a multi-tumor predisposition syndrome C Palles, HD West, E Chew, S Galavotti, C Flensburg, JE Grolleman, ... The American Journal of Human Genetics 109 (5), 953-960, 2022 | 40 | 2022 |
| Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes N Ansari-Pour, Y Zheng, TF Yoshimatsu, A Sanni, M Ajani, JB Reynier, ... Nature communications 12 (1), 6946, 2021 | 36 | 2021 |
| TFAP2A is a component of the ZEB1/2 network that regulates TGFB1-induced epithelial to mesenchymal transition Y Dimitrova, AJ Gruber, N Mittal, S Ghosh, B Dimitriades, D Mathow, ... Biology direct 12, 1-17, 2017 | 34 | 2017 |
| Terminal exon characterization with TECtool reveals an abundance of cell-specific isoforms AJ Gruber, F Gypas, A Riba, R Schmidt, M Zavolan Nature methods 15 (10), 832-836, 2018 | 31 | 2018 |
| Single‐cell mRNA profiling reveals the hierarchical response of mi RNA targets to mi RNA induction AJ Rzepiela, S Ghosh, J Breda, A Vina‐Vilaseca, AP Syed, AJ Gruber, ... Molecular systems biology 14 (8), e8266, 2018 | 28 | 2018 |
| The genomic landscape of 2,023 colorectal cancers AJ Cornish, AJ Gruber, B Kinnersley, D Chubb, A Frangou, G Caravagna, ... Nature 633 (8028), 127-136, 2024 | 26 | 2024 |
Mihaela ZavolanProfessor of Computational Biology, Biozentrum, University of BaselVerified email at unibas.ch