The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response A Baroja-Mazo, F Martín-Sánchez, AI Gomez, CM Martínez, ... Nature immunology 15 (8), 738-748, 2014 | 902 | 2014 |
Interleukin-17 is a negative regulator of established allergic asthma S Schnyder-Candrian, D Togbe, I Couillin, I Mercier, F Brombacher, ... The Journal of experimental medicine 203 (12), 2715-2725, 2006 | 798 | 2006 |
Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β AS Yazdi, G Guarda, N Riteau, SK Drexler, A Tardivel, I Couillin, ... Proceedings of the National Academy of Sciences 107 (45), 19449-19454, 2010 | 616 | 2010 |
IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice P Gasse, C Mary, I Guenon, N Noulin, S Charron, S Schnyder-Candrian, ... The Journal of clinical investigation 117 (12), 3786-3799, 2007 | 571 | 2007 |
Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis P Gasse, N Riteau, S Charron, S Girre, L Fick, V Pétrilli, J Tschopp, ... American journal of respiratory and critical care medicine 179 (10), 903-913, 2009 | 514 | 2009 |
Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis N Riteau, P Gasse, L Fauconnier, A Gombault, M Couegnat, L Fick, ... American journal of respiratory and critical care medicine 182 (6), 774-783, 2010 | 491 | 2010 |
Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent E Doz, N Noulin, E Boichot, I Guénon, L Fick, M Le Bert, V Lagente, ... The Journal of Immunology 180 (2), 1169-1178, 2008 | 400 | 2008 |
ATP release and purinergic signaling in NLRP3 inflammasome activation A Gombault, L Baron, I Couillin Frontiers in immunology 3, 414, 2013 | 357 | 2013 |
ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation N Riteau, L Baron, B Villeret, N Guillou, F Savigny, B Ryffel, F Rassendren, ... Cell death & disease 3 (10), e403-e403, 2012 | 292 | 2012 |
IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis P Gasse, N Riteau, R Vacher, ML Michel, A Fautrel, F Di Padova, L Fick, ... PloS one 6 (8), e23185, 2011 | 242 | 2011 |
The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine L Baron, A Gombault, M Fanny, B Villeret, F Savigny, N Guillou, C Panek, ... Cell death & disease 6 (2), e1629-e1629, 2015 | 227 | 2015 |
Specific vaccine therapy in chronic hepatitis B: induction of T cell proliferative responses specific for envelope antigens I Couillin, S Pol, M Mancini, F Driss, C Brechot, P Tiollais, ML Michel The Journal of infectious diseases 180 (1), 15-26, 1999 | 227 | 1999 |
NLRP3 inflammasome is required in murine asthma in the absence of aluminum adjuvant AG Besnard, N Guillou, J Tschopp, F Erard, I Couillin, Y Iwakura, ... Allergy 66 (8), 1047-1057, 2011 | 220 | 2011 |
Impaired cytotoxic T lymphocyte recognition due to genetic variations in the main immunogenic region of the human immunodeficiency virus 1 NEF protein. I Couillin, B Culmann-Penciolelli, E Gomard, J Choppin, JP Levy, ... The Journal of experimental medicine 180 (3), 1129-1134, 1994 | 216 | 1994 |
Inflammasome–IL-1–Th17 response in allergic lung inflammation AG Besnard, D Togbe, I Couillin, Z Tan, SG Zheng, F Erard, M Le Bert, ... Journal of molecular cell biology 4 (1), 3-10, 2012 | 203 | 2012 |
Cutting edge: crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1. 1− invariant NKT cells to bacteria JM Doisne, V Soulard, C Bécourt, L Amniai, P Henrot, ... The Journal of Immunology 186 (2), 662-666, 2011 | 185 | 2011 |
IL-17A–producing γδ T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis S Lo Re, L Dumoutier, I Couillin, C Van Vyve, Y Yakoub, ... The Journal of Immunology 184 (11), 6367-6377, 2010 | 173 | 2010 |
Toll‐like receptor and tumour necrosis factor dependent endotoxin‐induced acute lung injury D Togbe, S Schnyder‐Candrian, B Schnyder, E Doz, N Noulin, L Janot, ... International journal of experimental pathology 88 (6), 387-391, 2007 | 167 | 2007 |
The alarmin IL-1α is a master cytokine in acute lung inflammation induced by silica micro-and nanoparticles V Rabolli, AA Badissi, R Devosse, F Uwambayinema, Y Yakoub, ... Particle and fibre toxicology 11, 1-15, 2014 | 160 | 2014 |
ILr1β production is dependent on the activation of purinergic receptors and NLRP3 pathway in human macrophages T Gicquel, S Robert, P Loyer, T Victoni, A Bodin, C Ribault, F Gleonnec, ... The FASEB Journal 29 (10), 4162-4173, 2015 | 150 | 2015 |