Reactive oxygen species as a signal in glucose-stimulated insulin secretion J Pi, Y Bai, Q Zhang, V Wong, LM Floering, K Daniel, JM Reece, ... Diabetes 56 (7), 1783-1791, 2007 | 677 | 2007 |
ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function J Pi, Q Zhang, J Fu, CG Woods, Y Hou, BE Corkey, S Collins, ... Toxicology and applied pharmacology 244 (1), 77-83, 2010 | 411 | 2010 |
Toxicity testing in the 21st century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways S Bhattacharya, Q Zhang, PL Carmichael, K Boekelheide, ME Andersen PLoS One 6 (6), e20887, 2011 | 252 | 2011 |
A systems biology perspective on Nrf2-mediated antioxidant response Q Zhang, J Pi, CG Woods, ME Andersen Toxicology and applied pharmacology 244 (1), 84-97, 2010 | 241 | 2010 |
Signal amplification in the KEAP1-NRF2-ARE antioxidant response pathway S Liu, J Pi, Q Zhang Redox Biology, 102389, 2022 | 208 | 2022 |
Ultrasensitive response motifs: basic amplifiers in molecular signalling networks Q Zhang, S Bhattacharya, ME Andersen Open biology 3 (4), 130031, 2013 | 202 | 2013 |
An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy J Zhu, H Wang, F Chen, J Fu, Y Xu, Y Hou, HH Kou, C Zhai, MB Nelson, ... Free Radical Biology and Medicine 99, 544-556, 2016 | 191 | 2016 |
Adipose deficiency of Nrf2 in ob/ob mice results in severe metabolic syndrome P Xue, Y Hou, Y Chen, B Yang, J Fu, H Zheng, K Yarborough, CG Woods, ... Diabetes 62 (3), 845-854, 2013 | 185 | 2013 |
A deterministic map of Waddington's epigenetic landscape for cell fate specification S Bhattacharya, Q Zhang, ME Andersen BMC systems biology 5 (1), 85, 2011 | 179 | 2011 |
Doxorubicin-induced mitophagy and mitochondrial damage is associated with dysregulation of the PINK1/parkin pathway J Yin, J Guo, Q Zhang, L Cui, L Zhang, T Zhang, J Zhao, J Li, A Middleton, ... Toxicology in vitro 51, 1-10, 2018 | 174 | 2018 |
Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment Y Adeleye, M Andersen, R Clewell, M Davies, M Dent, S Edwards, ... Toxicology 332, 102-111, 2015 | 173 | 2015 |
Low-level arsenic impairs glucose-stimulated insulin secretion in pancreatic beta cells: involvement of cellular adaptive response to oxidative stress J Fu, CG Woods, E Yehuda-Shnaidman, Q Zhang, V Wong, S Collins, ... Environmental health perspectives 118 (6), 864-870, 2010 | 173 | 2010 |
Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis Y Hou, P Xue, Y Bai, D Liu, CG Woods, K Yarborough, J Fu, Q Zhang, ... Free Radical Biology and Medicine 52 (2), 462-472, 2012 | 149 | 2012 |
Prolonged inorganic arsenite exposure suppresses insulin-stimulated AKT S473 phosphorylation and glucose uptake in 3T3-L1 adipocytes: involvement of the adaptive antioxidant … P Xue, Y Hou, Q Zhang, CG Woods, K Yarborough, H Liu, G Sun, ... Biochemical and biophysical research communications 407 (2), 360-365, 2011 | 109 | 2011 |
Hepatocyte-specific Nrf2 deficiency mitigates high-fat diet-induced hepatic steatosis: Involvement of reduced PPARγ expression L Li, J Fu, D Liu, J Sun, Y Hou, C Chen, J Shao, L Wang, X Wang, R Zhao, ... Redox biology 30, 101412, 2020 | 100 | 2020 |
Dose response relationship in anti-stress gene regulatory networks Q Zhang, ME Andersen PLoS computational biology 3 (3), e24, 2007 | 100 | 2007 |
Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages CG Woods, J Fu, P Xue, Y Hou, LJ Pluta, L Yang, Q Zhang, RS Thomas, ... Toxicology and applied pharmacology 238 (1), 27-36, 2009 | 94 | 2009 |
Erythropoietin activates SIRT1 to protect human cardiomyocytes against doxorubicin-induced mitochondrial dysfunction and toxicity L Cui, J Guo, Q Zhang, J Yin, J Li, W Zhou, T Zhang, H Yuan, J Zhao, ... Toxicology letters 275, 28-38, 2017 | 89 | 2017 |
Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid J Pi, Q Zhang, CG Woods, V Wong, S Collins, ME Andersen Toxicology and applied pharmacology 226 (3), 236-243, 2008 | 89 | 2008 |
Bridging the Data Gap From in vitro Toxicity Testing to Chemical Safety Assessment Through Computational Modeling Q Zhang, J Li, A Middleton, S Bhattacharya, RB Conolly Frontiers in public health 6, 261, 2018 | 88 | 2018 |