| Tau activates transposable elements in Alzheimer’s disease C Guo, HH Jeong, YC Hsieh, HU Klein, DA Bennett, PL De Jager, Z Liu, ... Cell Reports 23 (10), 2874-2880, 2018 | 284 | 2018 |
| Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer’s Disease YC Hsieh, C Guo, HK Yalamanchili, M Abreha, R Al-Ouran, Y Li, ... Cell reports 29 (2), 301-316. e10, 2019 | 158 | 2019 |
| Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors VN Lagomarsino, RV Pearse, L Liu, YC Hsieh, MA Fernandez, EA Vinton, ... Neuron 109 (21), 3402-3420. e9, 2021 | 102 | 2021 |
| Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease AK Chouhan, C Guo, YC Hsieh, H Ye, M Senturk, Z Zuo, Y Li, ... Acta Neuropathologica Communications 4 (1), 62, 2016 | 85 | 2016 |
| Moving beyond amyloid and tau to capture the biological heterogeneity of Alzheimer’s disease TL Young-Pearse, H Lee, YC Hsieh, V Chou, DJ Selkoe Trends in Neurosciences 46 (6), 426-444, 2023 | 43 | 2023 |
| Integrated analysis of the aging brain transcriptome and proteome in tauopathy CG Mangleburg, T Wu, HK Yalamanchili, C Guo, YC Hsieh, DM Duong, ... Molecular Neurodegeneration 15 (1), 56, 2020 | 27 | 2020 |
| Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer’s disease risk gene SORL1 H Lee, AJ Aylward, RV Pearse, AM Lish, YC Hsieh, ZM Augur, CR Benoit, ... Cell reports 42 (8), 2023 | 26 | 2023 |
| APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer’s pathology in trisomy 21 neurons CI Wu, EA Vinton, RV Pearse, K Heo, AJ Aylward, YC Hsieh, Y Bi, ... Molecular Psychiatry 27 (4), 1970-1989, 2022 | 25 | 2022 |
| BCAS2 Regulates Delta-Notch Signaling Activity through Delta Pre-mRNA Splicing in Drosophila Wing Development MH Chou, YC Hsieh, CW Huang, PH Chen, SP Chan, YP Tsao, HH Lee, ... PloS one 10 (6), e0130706, 2015 | 14 | 2015 |
| Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity YC Hsieh, J Negri, A He, RV Pearse, L Liu, DM Duong, LB Chibnik, ... Molecular neurodegeneration 17 (1), 61, 2022 | 12 | 2022 |
| Association of AK4 Protein From Stem Cell–Derived Neurons With Cognitive Reserve: An Autopsy Study L Yu, YC Hsieh, RV Pearse, Y Wang, VA Petyuk, JA Schneider, ... Neurology 99 (20), e2264-e2274, 2022 | 7 | 2022 |
| Tau-mediated disruption of the spliceosome triggers cryptic rna splicing and neurodegeneration in Alzheimer’s disease. Cell Rep 29: 301-316. e10 YC Hsieh, C Guo, HK Yalamanchili, M Abreha, R Al-Ouran, Y Li, ... | 6 | 2019 |
| Tau activates transposable elements in Alzheimer’s Disease. Cell Rep. 2018; 23 (10): 2874–80 C Guo, HH Jeong, YC Hsieh, HU Klein, DA Bennett, PL De Jager, Z Liu, ... | 6 | |
| Person‐specific differences in ubiquitin‐proteasome mediated proteostasis in human neurons YC Hsieh, ZM Augur, M Arbery, N Ashour, K Barrett, RV Pearse, ES Tio, ... Alzheimer's & Dementia 20 (4), 2952-2967, 2024 | 4 | 2024 |
| P4‐130: TAU‐MEDIATED DISRUPTION OF THE SPLICEOSOME TRIGGERS CRYPTIC RNA SPLICING AND NEURODEGENERATION IN ALZHEIMER'S DISEASE C Guo, YC Hsieh, HK Yalamanchili, M Abreha, R Al-Ouran, Y Li, ... Alzheimer's & Dementia 15, P1325-P1325, 2019 | 1 | 2019 |
| SORL1 regulates the generation of APOE selectively in human neurons H Lee, AJ Aylward, RVP II, YC Hsieh, ZM Augur, A Knupp, S Goberdhan, ... Alzheimer's & Dementia 18, e067209, 2022 | | 2022 |
| Proteomic profiling of human brain coupled to functional assays for the identification of neurotoxic proteins YC Hsieh, J Negri, A He, RVP II, L Liu, DM Duong, LB Chibnik, ... Alzheimer's & Dementia 18, e059823, 2022 | | 2022 |
| Tau-mediated disruption of the spliceosome in Alzheimer's disease YC Hsieh Baylor College of Medicine, 2019 | | 2019 |
| P3‐179: TAU‐INDUCED DISRUPTION OF THE SPLICEOSOME IN ALZHEIMER'S DISEASE C Guo, YC Hsieh, HK Yalamanchili, M Abreha, D Duong, Y Li, ... Alzheimer's & Dementia 14 (7S_Part_21), P1136-P1136, 2018 | | 2018 |
| P3‐098: TAU‐Spliceosome Interactions in Drosophila Models of Alzheimer's Disease YC Hsieh, C Guo, M Zhao, Y Li, JM Shulman Alzheimer's & Dementia 12, P857-P857, 2016 | | 2016 |
