Metabolomics and isotope tracing C Jang, L Chen, JD Rabinowitz Cell 173 (4), 822-837, 2018 | 794 | 2018 |
Reversal of cytosolic one-carbon flux compensates for loss of the mitochondrial folate pathway GS Ducker, L Chen, RJ Morscher, JM Ghergurovich, M Esposito, X Teng, ... Cell metabolism 23 (6), 1140-1153, 2016 | 438 | 2016 |
NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism L Chen, Z Zhang, A Hoshino, HD Zheng, M Morley, Z Arany, ... Nature metabolism 1 (3), 404-415, 2019 | 313 | 2019 |
Metabolite exchange between mammalian organs quantified in pigs C Jang, S Hui, X Zeng, AJ Cowan, L Wang, L Chen, RJ Morscher, ... Cell metabolism 30 (3), 594-606. e3, 2019 | 227 | 2019 |
The tumor metabolic microenvironment: lessons from lactate JC García-Cañaveras, L Chen, JD Rabinowitz Cancer research 79 (13), 3155-3162, 2019 | 182 | 2019 |
Extraction and quantitation of nicotinamide adenine dinucleotide redox cofactors W Lu, L Wang, L Chen, S Hui, JD Rabinowitz Antioxidants & redox signaling 28 (3), 167-179, 2018 | 179 | 2018 |
Metabolite discovery through global annotation of untargeted metabolomics data L Chen, W Lu, L Wang, X Xing, Z Chen, X Teng, X Zeng, AD Muscarella, ... Nature methods 18 (11), 1377-1385, 2021 | 175 | 2021 |
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway JM Ghergurovich, JC García-Cañaveras, J Wang, E Schmidt, Z Zhang, ... Nature chemical biology 16 (7), 731-739, 2020 | 151 | 2020 |
Photoaffinity labeling of small-molecule-binding proteins by DNA-templated chemistry. G Li, Y Liu, Y Liu, L Chen, S Wu, Y Liu, X Li Angewandte Chemie International Edition 52 (36), 2013 | 122 | 2013 |
Chemical basis for deuterium labeling of fat and NADPH Z Zhang, L Chen, L Liu, X Su, JD Rabinowitz Journal of the American Chemical Society 139 (41), 14368-14371, 2017 | 103 | 2017 |
Peak annotation and verification engine for untargeted LC–MS metabolomics L Wang, X Xing, L Chen, L Yang, X Su, H Rabitz, W Lu, JD Rabinowitz Analytical chemistry 91 (3), 1838-1846, 2018 | 101 | 2018 |
NAD+ flux is maintained in aged mice despite lower tissue concentrations MR McReynolds, K Chellappa, E Chiles, C Jankowski, Y Shen, L Chen, ... Cell systems 12 (12), 1160-1172. e4, 2021 | 86 | 2021 |
The metabolites NADP+ and NADPH are the targets of the circadian protein Nocturnin (Curled) MA Estrella, J Du, L Chen, S Rath, E Prangley, A Chitrakar, T Aoki, ... Nature communications 10 (1), 2367, 2019 | 74 | 2019 |
Bridging targeted and untargeted mass spectrometry-based metabolomics via hybrid approaches L Chen, F Zhong, J Zhu Metabolites 10 (9), 348, 2020 | 72 | 2020 |
An LC-MS chemical derivatization method for the measurement of five different one-carbon states of cellular tetrahydrofolate L Chen, GS Ducker, W Lu, X Teng, JD Rabinowitz Analytical and bioanalytical chemistry 409, 5955-5964, 2017 | 49 | 2017 |
Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain SE McKee, S Zhang, L Chen, JD Rabinowitz, TM Reyes Journal of neurochemistry 145 (5), 362-373, 2018 | 42 | 2018 |
A two-enzyme adaptive unit within bacterial folate metabolism AF Schober, AD Mathis, C Ingle, JO Park, L Chen, JD Rabinowitz, I Junier, ... Cell reports 27 (11), 3359-3370. e7, 2019 | 36 | 2019 |
Photoaffinity labeling of transcription factors by DNA-templated crosslinking Y Liu, W Zheng, W Zhang, N Chen, Y Liu, L Chen, X Zhou, X Chen, ... Chemical Science 6 (1), 745-751, 2015 | 35 | 2015 |
Improved annotation of untargeted metabolomics data through buffer modifications that shift adduct mass and intensity W Lu, X Xing, L Wang, L Chen, S Zhang, MR McReynolds, JD Rabinowitz Analytical chemistry 92 (17), 11573-11581, 2020 | 24 | 2020 |
Identification of metabolite interference is necessary for accurate LC-MS targeted metabolomics analysis Z Jia, Q Qiu, R He, T Zhou, L Chen Analytical Chemistry 95 (20), 7985-7992, 2023 | 13 | 2023 |